107results about How to "Good suspension effect" patented technology

The invention provides medium-temperature and high-temperature clean fracturing fluid used under high formation temperature and a preparation method thereof. The clean fracturing fluid contains Gemini cation surfactant, amphoteric surfactant, electrolyte salt, counter-ion salt, cosolvent and water. The clean fracturing fluid of the invention is used for oil and gas field fracturing and mainly comprises 2-5 percent of surfactant, 1-4 percent of amphoteric surfactant, 1-4 percent of electrolyte, 0.05-0.15 percent of counter ion and 0.1-1.5 percent of cosolvent by weight percent. Viscoelastic fluid is formed under agitation. The invention has the advantages that the viscoelasticity of the system is high, the friction resistance is low and good sand suspending performance is kept within 90-130 DEG C.

The invention discloses a cationic viscoelastic surfactant and preparation and application thereof. The preparation method of the cationic viscoelastic surfactant comprises the following steps: firstly, mixing long-chain fatty acid with dimethylaminopropylamine according to a certain proportion, adding a catalyst solution to obtain a required amide product intermediate A by a series of reaction; allowing reflux condensation reaction of epoxy chloropropane and water at a certain proportion to be carried out in oil bath of 100 DEG C to obtain colourless and transparent 3-chloro-1,2-propylene glycol aqueous solution, namely an intermediate B; heating the intermediate A in oil bath for melting, and dropwise adding an aqueous solution B to obtain the required viscoelastic surfactant by a series of reaction; the surfactant can be mixed with a potassium chloride solution according to a certain proportion to obtain clean fracturing fluid which is low in cost and excellent in performance, besides, the clean fracturing fluid has excellent high-temperature resistance, shearing resistance, and excellent solid-carrying performance, is automatic and thorough in gel breaking, causes little damage to the reservoir stratum and has the characteristic of wide application range.

The invention relates to a preparation having the functions of promoting blood circulation, enlivening spleen and tonifying kidney, the process for preparation and quality control method, wherein the preparation is produced mainly from astragalus root, Chinese ephedra, Chinese angelica root, herba ecliptae, atractylodes rhizome, safflower, radix paeoniae rubrathe, peach kernels, achyranthes and cyathula root, Ligusticum wallichii, bitter orange and root of balloonflower. The preparation can be made into injections and various oral administration preparations including dripping pills, mini-pills and dispersible tablets. The invention also provides the method for determining and identifying contents of the preparation.

The invention relates to a composition used for preparing a temperature-resistant salt-resistant fracturing fluid thickening agent, the temperature-resistant salt-resistant fracturing fluid thickeningagent prepared from the composition, and a preparation method thereof. The composition comprises following components: acrylamide, acrylic acid, a hydrophobic monomer, 2-acrylamido-2-methylpropane sulfonic acid, a rigid monomer, a surfactant, and a shielding reagent. According to the temperature-resistant salt-resistant fracturing fluid thickening agent, excellent sand suspension effect can be achieved without crosslinking with a crosslinking agent, the temperature resistance and salt resistance are better; after 2h of aging in a simulated brine with total mineralization degree of 50000mg / L at 160 DEG C, the viscosity retention rate of the temperature-resistant salt-resistant fracturing fluid thickening agent is equal to or larger than 80%. Solution gel breaking of the temperature-resistant salt-resistant fracturing fluid thickening agent is complete, no water insoluble substance is left, flowback is complete, the ground is not destroyed, and no oil layer pollution is caused.

The invention discloses an efficient salt-resistant dual-purpose thickening agent, a preparation method and application thereof. The preparation method of the thickening agent comprises the followingsteps of: S1, preparing a water phase; S2, preparing an oil phase; S3, performing emulsifying; S4, conducting polymerization; and S5, carrying out aftertreatment. A hydrophobic monomer, a functional monomer and a salt-resistant monomer are introduced into the thickening agent to form a compact and complex spatial network structure in an aqueous solution, so that the thermal stability and the saltresistance of the thickening agent are improved, and the aqueous solution of the thickening agent can keep relatively high viscosity under a hypersalinity condition. Due to the addition of a chain extender, the molecular chain of the polymer is longer, and the viscosity is greatly improved. A cosolvent is introduced, so that the dissolving speed of a polymer emulsion is further increased, the polymer emulsion can be completely dissolved in 30 seconds, the requirement on water quality is low, and the polymer emulsion can be prepared from oilfield reinjection water and oilfield wastewater. Due to the addition of a suspending agent, the emulsion system is more stable, and the emulsion is not layered within two years. The thickening agent also has the characteristic of dual purposes, and can be used as a fracturing fluid slickwater drag reducer and a fracturing fluid thickening agent.

The invention relates to the technical field of animal medicine, and particularly discloses veterinary long-acting cefquinome sulfate injection and a preparation method thereof. 100 mL of the injection comprises 2.5-7.5 g of cefquinome sulfate, 0.2-0.4 g of suspending agents, 0.4 g of bacteriostatic agents, 0.3 g of emulsion dispersants, and the balance of solvents. The preparation method comprises the following steps: firstly adding cefquinome sulfate into the solvent, stirring for well mixing; adding the suspending agent into the solvent with a temperature of 90-100 DEG C for dissolution; cooling the dissolved solution in the second step to room temperature, adding the suspension under stirring in the first step, uniformly stirring; adding the bacteriostatic agent and the emulsion dispersant in to the suspension in the third step, fully stirring; finally adding residual amount of the solvent, uniformly stirring, orderly adding the mixture into a high-speed shearing dispenser and a colloid mill, performing radiation sterilization to prepare the product. When the product is used in pigs by intramuscular injection, the elimination half life is long; the effective action time of themedicine in the body is prolonged; and the drug administration time is reduced.

The invention discloses a novel polymeric visco-elastic surfactant, and a preparation method and an application thereof. The method comprises the following steps: 1, preparing an amide product intermediate A from fatty acid and dimethylaminopropylamine; 2, placing dichloroethane, diethanolamine, NaOH and ethanol in a reaction container, carrying out a reflux reaction for 20-24 h, cooling the obtained reaction product to room temperature, and removing ethanol to obtain an intermediate B; and 3, adding the amide product intermediate A and the intermediate B into the reaction container, adding ethanol, mixing the intermediates and ethanol, and carrying out a reflux reaction for 10-12 h to obtain the novel polymeric visco-elastic surfactant. The novel polymeric visco-elastic surfactant prepared through the method can be used for preparing a low-cost high temperature-resistant clean fracturing fluid to improve the high temperature resistance, the shear resistance and the suspended sand performance of the fracturing fluid.

The invention discloses a lamotrigine dry suspension. The lamotrigine dry suspension comprises lamotrigine and other pharmaceutical-grade auxiliary materials, wherein the auxiliary materials include a filling agent, a suspending aid, a buffer agent, a sweetening agent, a flavor agent and a flow aid. The lamotrigine dry suspension has the advantages of liquid suspensions that the taste of medicines is improved, the medicines are easy to be taken, and the stability of medication dosage is improved; furthermore, the chemical and physical stabilities of a preparation can be improved, and the quality of the lamotrigine dry suspension is improved.

The invention relates to the field of pharmaceutical preparations, especially to a cefixime granule and a one-step granulating method of the cefixime granule. The cefixime granule comprises the following components by weight: 1-20% of cefixime, 56-95% of diluent, 0.5-1.0% of a buffer agent, 0.5-10% of adhesive and 0.1-5% of flavoring. The cefixime granule has the advantages of good quality stability, good suspension property and good content uniformity, and good taste simultaneously, so that the cefixime granule is especially suitable for children and crowd of dysphagia, and medication compliance is good. A preparation method of the cefixime granule further is provided by the invention; due to use of the one-step granulating method, steps of mixing, granulating and drying are finished in the same one fluidized bed by one step; operation method is simple, and production efficiency is high, so that the preparation method is especially suitable for industrial production.

The invention discloses a shear-resistant low-concentration guar gum zirconium gel fracturing fluid which comprises at least the following components by weight: 0.2-0.6% of carboxymethyl hydroxypropylguar gum, 0.1%-0.4% of a clay stabilizer, 0.2%-0.4% of a discharge aiding agent, 0.2%-0.4% of a crosslinking agent, 0.1%-0.3% of a rheology modifier, a pH adjuster with a dosage capable of keeping the pH of the fracturing fluid at 10 to 12, and balance of water. The rheology modifier is selected from urea and thiourea. The rheology modifier is added to control the cross-linking rate of the carboxymethyl hydroxypropyl guar gum and the organic zirconium crosslinking agent, and the stability of the zirconium gel fracturing fluid under high shear can be improved. The shear-resistant low-concentration guar gum zirconium gel fracturing fluid has low use concentration, can resist high shear, and has good suspended sand performance, and the use temperature is less than 170DEG C.

The invention belongs to the technical field of oilfield fracturing stimulation, and particularly relates to a recyclable fracturing fluid and a preparation method thereof. The fracturing fluid is prepared from the following main raw materials in parts by weight: 0.2-0.35 part of a guar gum derivative thickener, 0.02-0.035 part of a cross-linking agent, 0.01-0.03 part of a pH regulator, 1 part of a fluid loss additive, 1 part of a bactericide and 92.1-96.5 parts of water. The recyclable fracturing fluid has the advantages of high flowback fluid recycling rate, and capabilities of turning waste into treasure, saving materials and water resource, reducing pollution discharge and reducing the pressure of water for underground operation.

A durable micro-spherical suspension of huperzine A without sudden release for treating senile hypomnesia and AD is disclosed. Its preparing process features that the PLGA-COOH or PLA-COOH is used and its process is simplified. Its action period is 20-40 days.

The invention discloses an underground coal mine hydraulic sand fracturing system and method. The underground coal mine hydraulic sand fracturing system comprises a water supply system, a fluid distribution system, a sand mixing system, a fracturing system and a high-pressure manifold system; the fracturing system is formed by two fracturing pump groups in parallel; the high-pressure manifold system comprises a Y-shaped tee, and two inlet channels of the Y-shaped tee separately communicate with outlets of the two fracturing pump groups; and the fluid distribution system comprises two fluid distribution pools. The fracturing method is implemented based on the fracturing system and comprises the steps that fracturing liquid is prepared by densifiers, crosslinking agents, anti-swelling agents, gel breakers and water according to proportion; the particle size of a supporting agent is 40-70 meshes, and the volume density of ceramsite sand is 1.25g / cm<3>; and fracturing is carried out according to the sequence of first hydraulic fracturing seam generating and later fracturing liquid sand-carrying fracturing support. The underground coal mine hydraulic sand fracturing system has the beneficial effects that the fracturing system is simple in structure and reasonable in layout, and is suitable for sand-carrying fracturing use of underground narrow and small or long and narrow space; andthe fracturing liquid prepared by the fracturing method has suspended sand characteristic, can be suitable for upward drilling sand-carrying fracturing, and has the environmental protection characteristic of being capable of directly discharged.

The invention relates to an automatic forming machine with dual-slurry suction, cold-extrusion and two-segment hot pressing and for a molding product and a manufacturing method for the molding product. A slurry suction upper die and a slurry suction lower die suck slurry at the same time, so upper and lower blank layers can be finished; cold die extrusion can be accomplished by a cold press upperdie and a cold press lower die of a cold press die mechanism; the slurry suction upper die and the slurry suction lower die are combined, so the upper and lower blank layers can be overlapped and a thick blank product with doubled thickness can be formed; and then segment-hot pressure sizing work is conducted. By the use of the manufacturing method and the automatic forming machine, assembling space can be reduced and manufacturing speed can be accelerated; molding product thickness can be increased and damping space can be added, so buffering and damping effect can be enhanced; and the surface of the molding product is smooth.

The invention relates to a turnover double pulp sucking automatic molding machine for a molded product and a production method of the molded product. According to the method provided by the invention,upper and lower pulp sucking molds respectively enter a pulp box to suck a pulp at the same time to form an upper blank material layer and a lower blank material layer, cold mold extrusion is quicklycompleted through driving of a turnover mechanism, the upper and lower pulp sucking molds are closed to make the upper and lower blank material layers combined to form a thick blank product with a double thickness, and hot pressure molding is performed through hot press upper and lower molds; the machine provided by the invention has the practical effects of simplifying assembly space, accelerating the production speed, increasing the thickness and shock absorbing space of the molded product, gaining the buffering shock-absorbing effects, and making the surfaces smooth.

The invention provides clean high-temperature water-base fracturing fluid. The clean high-temperature water-base fracturing fluid comprises components including, by weight, 0.5%-6% of clay stabilizers, 2%-6% of accelerators, 0.01%-0.1% of bactericides, 0.6%-3.0% of alcohol with a low molecular weight, 0.4%-2% of zwitterionic surfactants, 0%-0.5% of polysaccharide compounds and the balance water. The components are mixed with one another to obtain the clean high-temperature water-base fracturing fluid. The clean high-temperature water-base fracturing fluid has the advantages that as proved by indoor evaluation, the temperature resistance of the clean high-temperature water-base fracturing fluid can reach 150 DEG C at least, and accordingly the clean high-temperature water-base fracturing fluid is superior to general clean fracturing fluid systems; the dosage of betaine is 0.4%-2% (a weight ratio) and is far lower than the dosage (2%-5%) of amphoteric surfactants in formulas for conventional fracturing fluid; the clean high-temperature water-base fracturing fluid is convenient to use and operate, excellent in sand suspension ability and superior to common cross-link guar gum and quaternary ammonium salt systems, and cross-link can be omitted.

The invention discloses a nano-composite initiator which comprises at least one of composite compounds as shown in a formula I in the specification. The invention further discloses a thickening agent for the fracturing fluid, and application of the thickening agent in preparation of the fracturing fluid, wherein the raw materials of the thickening agent comprise the nano-composite initiator. The thickening agent for the fracturing fluid provided by the invention has the characteristics of rapid dissolution, high temperature resistance and good sand-carrying property, can form a high-temperature fracturing fluid system which is efficient in performance and convenient to use on site, and can meet the application requirements of a large-scale hydraulic fracturing construction process.

The invention relates to a low-temperature-resistant online variable-viscosity agent and a preparation method thereof. The method comprises the following steps: fully and uniformly mixing a water-phase solution, an oil-phase solution, an azo initiator and an oxidizing agent, emulsifying, pumping a reducing agent to initiate polymerization, adding a long-chain flexible monomer in the polymerization process, adding a hydrolytic agent for hydrolysis after the reaction is finished, adding a phase inversion agent after the hydrolysis is finished, and uniformly stirring to obtain the variable-viscosity agent. The aqueous phase solution is prepared from acrylamide, 2-acrylamido-2-methylpropanesulfonic acid, methacryloyloxyethyl-N, N-dimethyl propanesulfonate, sodium hydroxide, a structure regulator, a pour point depressant and water; the oil phase solution comprises an oily solvent, an emulsifier, a suspending aid and a penetrant. The variable-viscosity agent prepared by the invention has the characteristic of dual purposes, has an extremely high drag reduction effect under the condition of a low-concentration polymer solution, and has an extremely good thickening and sand-carrying effect after the concentration of the polymer is properly increased.

The invention provides a decoquinate preparation as well as a preparation method and application thereof. According to the method provided by the invention, raw materials and auxiliary materials are low in price and a preparation process is simple; large-size high-end equipment is not needed and the decoquinate preparation can be relatively convenient and rapid to prepare; meanwhile, the prepared preparation has good dissolubility and dissolution. Meanwhile, in the preparation, decoquinate is matched with components including a wetting agent, a dispersant, a lipophilic surfactant, a soluble diluting agent and the like, so that tote dissolution of decoquinate can be effectively improved; furthermore, decoquinate can also be prepared into granules, tablets, dry suspension agents or premixing agents and meets the utilization requirements of different occasions; meanwhile, the decoquinate preparation can also be used for preparing medicines for treating coccus diseases and can achieve a good treatment effect.

The invention relates to a production method for the double-pulp-suction cold-pressing double-section hot-pressing automatic shaping of molded products. A double-pulp-suction cold-pressing double-section hot-pressing automatic shaping machine is applied, an upper pulp-sucking mold and a lower pulp-sucking mold simultaneously suck pulp to form an upper preform layer and a lower preform layer, and then simultaneously carry out cold die-pressing along with a cold-pressing upper mold and a cold-pressing lower mold of a cold-pressing die mechanism, the upper pulp-sucking mold and the lower pulp-sucking mold are then closed to combine the upper preform layer and the lower preform layer into a thickness-doubled thick preform, and the thickness-doubled thick preform then undergoes two-section hot-pressing shaping operation. The production method has the following practical effects: the assembly space is saved, the production speed is increased, the thickness and shock-absorbing space of moldedproducts are increased, so that the cushioning and shock-absorbing effect is enhanced, and surfaces are all smooth surfaces.

The invention belongs to the technical field of nutrient foods and particularly relates to double-protein full-nutrient formula food and a preparation method thereof. The double-protein full-nutrientformula food contains nutrient elements such as proteins, fat, carbohydrate, vitamins and minerals. Soybean protein and whey protein are compounded and the two proteins complement each other, so thatthe food is easy to digest and absorb, can be used as a single nutrient source to meet nutrient requirements of patients suffering from feeding limitation and digestive absorption dysfunction, can provide sufficient and comprehensive nutrients for bodies and has the characteristics of small granules, good stability, low energy consumption and excellent product quality and production technologies.The double-protein full-nutrient formula food is low in cost and suitable for long-term eating by low-income earners, can improve the nutrient conditions of patients and has great significance in preventing infection, reducing complications, shortening length of stay, improving the quality of life of patients and prolonging life time.

The present invention relates to the field of medical tracer diagnosis reagent. The nano carbon is an ideal trancer. Said invention relates to a nano carbon suspension injection, and is characterized by that in said injection the carbon whose grain size is 80 nm is adopted, and the polyvinyl pyrrolidone (PVP-K30) suspension adjuvant is added, then the above-mentioned materials are undergone the processes of magnetic stirring, reflux and ultrasonic treatment so as to obtain the invented nano carbon suspension injection.

The invention discloses a cross-linked oil-in-water emulsified fracturing fluid, which belongs to a fracturing fluid technology and mainly solves the problem that the conventional fracturing fluid cannot meet the environmental requirements easily. The cross-linked oil-in-water emulsified fracturing fluid comprises the following components in percentage by mass: 2 percent of KCl, 0.45 percent of super guar gum, 0.6 percent of compound emulsifying agent, 0.15 percent of cleanup additive, 0.5 percent of emulsion splitter, 1 percent of clay stabilizer, 0.1 percent of modifier, 5 percent of diesel oil and the balance of water. The using effect of the fracturing fluid can be enhanced to a great extent, complete gel breaking is achieved by the fracturing fluid, and bonding capability is enhanced.

The invention relates to the technical field of medicines and medicine production, in particular to an empagliflozin dry suspension and a preparation method thereof. The empagliflozin dry suspension is prepared from the components in percentage by weight: 1-10% of empagliflozin, 55-80% of filler, 10-20% of a suspending aid, 0.1-2% of a lubricant, 8-15% of a disintegrating agent and 0.05-1% of a flavoring agent. The preparation method comprises the following steps that (1), the empagliflozin and the filler are co-crushed, and sieving is carried out after crushing to obtain a mixture of empagliflozin and the filler; (2), the filling agent, the disintegrating agent and the lubricating agent are weighed and sieved, the mixture obtained in the step (1) is added, uniform mixing is carried out, and a wetting agent is added to prepare a soft material; (3), the soft material obtained in the step (2) is prepared into particles, dried, sieved and granulated; and (4), the particles obtained in the step (2) is uniformly mixed with a suspending aid and a flavoring agent, and sub-packaging is carried out to obtain the empagliflozin dry suspension. When the empagliflozin dry suspension is taken, the empagliflozin dry suspension can be dispersed into a uniform suspension by adding water and shaking, so that the distribution area of the empagliflozin dry suspension in vivo is increased, and the empagliflozin dry suspension is rapidly absorbed and converted into a structure with pharmacological action in digestive tracts.

The present invention belongs to the technical field of nutritious foods, and especially relates to a rectal cancer nutritious food and a preparation method thereof. The rectal cancer nutritious foodcontains nutrient elements including proteins, fat, carbohydrate, vitamins, minerals, ginkgo flavonoids and phytosterol. The nutritious food provided by the invention can provide sufficient and comprehensive nutrients for the organism, more importantly, the food enhances the barrier function of intestinal mucosa, better accords with the metabolic physiological state, facilitates the protein synthesis and metabolism regulation of the organism, promotes the recovery of intestinal function and form, prevents bacteria and toxin translocation, obviously reduces the occurrence of intestinal source infection, and is an effective way to improve the nutritional status of chemotherapy patients. The food has a certain improvement effect on the nutritional status of chemotherapy patients with middle or advanced rectal cancer, can reduce adverse reaction of patients, and can effectively improve the immunity of patients.

The invention discloses a fracturing liquid system with small friction resistance and good sand suspension. The fracturing liquid system comprises the following components in percentage by mass: 0.1-0.3wt% of a polymer thickening agent, 0.015-0.02wt% of a surfactant cross-linking agent, 0.04-0.08wt% of a gel breaker and the balance of water, wherein the polymer thickening agent is prepared from acrylamide, acrylic acid, a rigid monomer and a cationic hydrophobic monomer in a weight ratio of (75-80):(15-20):(2.0-5.0):(1.0-3.0) through polymerization; the polymerization temperature is 10-30 DEGC; the polymerization time is 8-10 hours. By adopting a fracturing liquid of the fracturing liquid system, the technical problems that a conventional fracturing liquid is large in friction resistanceand poor in sand suspension in the pumping process are solved.

The invention relates to the field of pharmaceutical preparations and particularly relates to cefixime granules and a one-step granulation method thereof. The cefixime granules contain the following ingredients in percentage by weight: 1% to 20% of cefixime, 56% to 95% of diluent, 0.5% to 10% of buffer, 0.5% to 10% of binder and 0.1% to 5% of flavoring agent. The cefixime granules have very good quality stability, suspension performance and content uniformity and meanwhile have very good mouth feel, so that the cefixime granules are especially suitable for children and dysphagic people, and the medication compliance is good. The invention further provides a preparation method of the cefixime granules. The one-step granulation preparation method is used, and mixing, granulating and drying are completed in one step in the same fluidized bed, so that the operating step is simple, the production efficiency is high, the preparation method is especially applicable to industrial production.

The present invention discloses a compound long-acting injection containing enrofloxacin and meloxicam. The compound long-acting injection comprises the enrofloxacin and / or a salt thereof, the meloxicam in a dispersion form, a meloxicam solid dispersoid, a high molecular retardant, a wetting agent and a dispersion medium; each 1,000 mL of the injection contains 20-250 g of the enrofloxacin and / orthe salt thereof (calculated by the enrofloxacin), 5-50 g of the meloxicam in the dispersion form, 5-30 g of the high molecular retardant, 5-20 g of the wetting agent, and the balance of a dispersionmedium; and a mass ratio of the meloxicam in the dispersion form to the meloxicam solid dispersoid (calculated by the meloxicam) is (5:1)-(1:1). The injection preparation is stable in quality, slow indrug release, safe and effective, only 1-2 times of drug administration in one course of treatment can treat both symptoms and root causes, and effective blood drug concentration is maintained for 3-7 days; and only 1 needle is used for injection for 1 time, so that the compound long-acting injection enhances animal compliance, reduces animal stress and is more favorable for disease outcome and prognosis.

The invention discloses a suspension device for a small-sized multifunctional chassis. The suspension device is characterized in that a vertical supporting seat is vertically fixed with a frame of the small-sized multifunctional chassis; the front end of the vertical supporting seat is provided with a lifting lug and an oil cylinder; the rear end of the vertical supporting seat is provided with a reinforcing rib which is fixed with the frame; the top end of the vertical supporting seat is connected with an upper seat; the oil cylinder is provided with an oil inlet and outlet opening which is connected with an oil pipe; the upper end of the upper seat is provided with a steel wire rope in a rotating pipe supporting rope mechanism and can move with the steel wire rope; and the steel wire rope is connected with an elevating mechanism and drives the elevating mechanism to rotate around a rotating shaft. The suspension device provided by the invention is specially designed for small-sized agricultural power machines and tools, occupies small space, consumes less energy, has light weight, well solves the problem of suspension plowing of small-sized agricultural machines and tools, especially solves the problem of difficult adjustment of a penetrating angle of a suspension plowshare, and effectively realizes real-time adjustment of the penetrating angle of a plowshare, so the depth of plowing is limited; the quality of plowing is improved; the labor intensity is lightened; and the efficiency of plowing is improved.