Traditional Chinese medicine granules treating schizophrenia and preparation method thereof

A technology of schizophrenia and granules, which is applied in the field of medicine, can solve problems such as extrapyramidal adverse reactions, autonomic disorders, palliatives but not the root cause, and achieve a wide application range, strong pertinence, and remarkable effects

Inactive Publication Date: 2015-10-28
王丽萍
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] In the treatment of schizophrenia, antipsychotic drugs are currently the most widely used treatment, and now mainly Western medicine treatment, such as the first-generation drug: haloperidol (haloperidol), the second-generation drug clozapine ( clozapine), risperidone (rispeoidone) can relieve many symptoms, but the cure rate is very low, the curative effect is not good, and there are often adverse reactions of extrapyramidal system and autonomic disorder, such as weight gain, hyperglycemia, hyperlipidemia, Sexual dysfunction and menstrual disorders caused by persistent hyperprolactinemia, and even side effects such as liver function, blood picture abnormalities, and ECG changes, and patients need to rely on drugs for life. According to Mate analysis in recent years, these drugs have limited efficacy. Treat the symptoms but not the root cause, so there is an urgent need to develop a Chinese medicine for the treatment of schizophrenia with good curative effect and little side effects

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0043] A traditional Chinese medicine granule for treating schizophrenia, comprising the following raw materials in parts by weight: 6 parts of lotus leaves, 5 parts of orange peel, 15 parts of mulberry, 6 parts of Alisma, 9 parts of ginger, 6 parts of Achyranthes bidentata, and mallow seeds 7 parts, 10 parts of coix seed, 4 parts of purple pearl, 6 parts of agrimony, 4 parts of hawthorn, 10 parts of forsythia, 5 parts of peony bark, 9 parts of perilla seed, and 10 parts of auxiliary materials.

[0044] The auxiliary materials of the present invention include the following raw materials in parts by weight: 20 parts of sucrose, 10 parts of starch and 20 parts of dextrin.

[0045] The method for preparing described electuary, comprises the following steps:

[0046] 1) Add water to decoct lotus leaf, orange peel, mulberry, Alisma, ginger, Achyranthes bidentata, mallow seed, coix seed, big leaf purple pearl, agrimony, hawthorn, forsythia, moutan bark, and white perilla , add wate...

Embodiment 2

[0049] A traditional Chinese medicine granule for treating schizophrenia, comprising the following raw materials in parts by weight: 7 parts of lotus leaves, 6 parts of orange peel, 25 parts of mulberry, 8 parts of Alisma, 9 parts of ginger, 8 parts of Achyranthes bidentata, and mallow seeds 8 parts, 12 parts of coix seed, 6 parts of big leaf purple pearl, 8 parts of agrimony, 6 parts of hawthorn, 12 parts of forsythia, 7 parts of peony bark, 12 parts of perilla seed, 20 parts of auxiliary materials.

[0050] The auxiliary materials of the present invention include the following raw materials in parts by weight: 30 parts of sucrose, 15 parts of starch and 50 parts of dextrin.

[0051] The method for preparing described electuary, comprises the following steps:

[0052] 1) Add water to decoct lotus leaf, orange peel, mulberry, Alisma, ginger, Achyranthes bidentata, mallow seed, coix seed, big leaf purple pearl, agrimony, hawthorn, forsythia, moutan bark, and white perilla , ad...

Embodiment 3

[0055] A traditional Chinese medicine granule for treating schizophrenia, comprising the following raw materials in parts by weight: 8 parts of lotus leaves, 7 parts of orange peel, 30 parts of mulberry, 10 parts of Alisma, 10 parts of ginger, 10 parts of Achyranthes bidentata, mallow seeds 9 parts, coix seed 15 parts, big leaf purple pearl 8 parts, agrimony 10 parts, hawthorn 9 parts, forsythia 15 parts, moutan bark 9 parts, perilla seed 15 parts, auxiliary materials 30 parts.

[0056] The auxiliary materials of the present invention include the following raw materials in parts by weight: 40 parts of sucrose, 20 parts of starch and 70 parts of dextrin.

[0057] The method for preparing described electuary, comprises the following steps:

[0058] 1) Add water to decoct lotus leaf, orange peel, mulberry, Alisma, ginger, Achyranthes bidentata, mallow seed, coix seed, big leaf purple pearl, agrimony, hawthorn, forsythia, moutan bark, and white perilla , add water 7 times for the...

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PUM

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Abstract

The invention discloses traditional Chinese medicine granules treating schizophrenia and a preparation method thereof. The granules comprise, by weight, 6-8 parts of lotus leaves, 5-7 parts of orange peel, 15-30 parts of herba taxilli, 6-10 parts of rhizoma alismatis, 9-10 parts of fresh gingers, 6-10 parts of achyranthes roots, 7-9 parts of cluster mallow fruits, 10-15 parts of coix seeds, 4-8 parts of big-leaf beautyberry leaves, 6-10 parts of agrimonia pilosa, 4-9 parts of hawthorn fruits, 10-15 parts of phillyrin, 5-9 parts of moutan bark, 9-15 parts of common perilla fruits and 10-30 parts of auxiliary materials. The granules start from phlegm, emphasize regulation of qi-flowing for eliminating phlegm, have effects on various types of schizophrenia and greatly relieve positive symptoms, negative symptoms and cognitive function impairment of schizophrenia to a large extent. Meanwhile, the selected traditional Chinese medicine formula of the granules is good in safety and low in price, and the traditional Chinese medicine granules have the advantages that people can conveniently take the granules after mixing the granules with water, taste is good, and the granules are easy to carry.

Description

technical field [0001] The invention relates to the technical field of medicines, in particular to a traditional Chinese medicine granule for treating schizophrenia and a preparation method thereof. Background technique [0002] Schizophrenia is a clinically common disease that endangers human health. It is a chronic, severe, and disabling encephalopathy. The lifetime prevalence of schizophrenia in the world is 0.38%-0.84%. The morbidity rate is not the highest, but it is the most serious mental illness. According to the Lancet survey in 2009, the number of schizophrenia patients in my country is nearly 10 million. The cost of schizophrenia treatment is high. According to statistics, the total cost of schizophrenia treatment in the United States in 2002 reached 62.7 billion U.S. dollars, of which 22.7 billion U.S. dollars were direct costs, and 32.4 billion were losses caused by early death due to suicide and family members taking care of patients. Schizophrenia is highly di...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/9068A61K9/16A61P25/18
Inventor 王丽萍
Owner 王丽萍
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