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Kamailitong capsules for treating cardiovascular and cerebrovascular diseases and preparation method of capsules

A cardiovascular and cerebrovascular disease, Kamailitong technology, applied in the direction of cardiovascular system diseases, blood diseases, capsule delivery, etc., can solve the problems of high toxicity and side effects, poor curative effect, expensive price, etc., to achieve stable curative effect, no toxic and side effects, low cost effect

Inactive Publication Date: 2015-11-18
郭冠英
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The market demand for prevention and treatment is particularly large. At present, although there are many drugs for the treatment of such diseases on the market, there are few drugs with definite curative effect and long-lasting effects, and even fewer drugs with preventive functions, either because of high price or high toxicity and side effects. , or due to poor curative effect, it is still difficult to meet the needs of the majority of patients

Method used

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  • Kamailitong capsules for treating cardiovascular and cerebrovascular diseases and preparation method of capsules
  • Kamailitong capsules for treating cardiovascular and cerebrovascular diseases and preparation method of capsules
  • Kamailitong capsules for treating cardiovascular and cerebrovascular diseases and preparation method of capsules

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preparation example Construction

[0025] The preparation method of capsule of the present invention comprises the following steps:

[0026] 1. Accurately weigh 5 decoction pieces of red ginseng, salvia miltiorrhiza, angelica, chuanxiong and hawthorn according to the above formula, add ethanol with a volume fraction of 72% to 78% for reflux extraction twice, and add 7 times the amount (referring to the weight of the original medicinal material) for the first time ) ethanol reflux extraction for 2 hours, the second 6 times the amount of ethanol (referring to the weight of the original medicinal material) reflux extraction for 2 hours, filter, combine the extracts, recover ethanol under reduced pressure, and concentrate until the relative density measured at 60 ° C is 1.31 to 1.33 The extract is ready for use.

[0027] 2. Accurately weigh the astragalus decoction pieces according to the formula, combine them with the dregs in step 1, add water to decoct twice, add 12 times the amount (the weight of astragalus and...

Embodiment 1

[0046] In parts by weight, the contents include 660g of astragalus, 70g of red ginseng, 250g of salvia miltiorrhiza, 150g of angelica, 150g of chuanxiong, 150g of hawthorn, 100g of leech, 100g of earthworm, 50g of dried blood and 30g of borneol.

[0047] Concrete preparation steps are as follows:

[0048] 1. Accurately weigh the 5 decoction pieces of red ginseng, salvia miltiorrhiza, angelica, chuanxiong and hawthorn according to the above formula, add 75% ethanol to reflux for extraction twice, add 7 times the amount (referring to the weight of the original medicinal material) ethanol to reflux for the first time Extract for 2 hours, add 6 times the amount of ethanol for the second time to reflux for 2 hours, combine the extracts, filter, recover ethanol under reduced pressure, and concentrate to an extract with a thermal relative density of 1.32 at 60°C for future use.

[0049] 2. Accurately weigh the astragalus decoction pieces according to the formula, combine them with th...

Embodiment 2

[0096] In parts by weight, the contents include astragalus 600g, red ginseng 60g, salvia miltiorrhiza 200g, angelica 130g, chuanxiong 120g, hawthorn 120g, leech 80g, earthworm 80g, blood jerky 40g and borneol 25g.

[0097] Concrete preparation steps are as follows:

[0098] 1. Accurately weigh 5 decoction pieces of red ginseng, salvia miltiorrhiza, angelica, chuanxiong and hawthorn according to the above formula, add ethanol with a volume fraction of 72% to reflux for extraction twice, add 7 times the amount of ethanol (referring to the weight of the original medicinal materials) for the first time and reflux Extract for 2 hours, add 6 times the amount of ethanol for the second time to reflux for 2 hours, combine the extracts, filter, recover ethanol under reduced pressure, and concentrate to an extract with a thermal relative density of 1.31 at 60°C for future use.

[0099] 2. Accurately weigh the astragalus decoction pieces according to the formula, combine them with the dre...

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Abstract

The invention relates to kamailitong capsules for treating cardiovascular and cerebrovascular diseases and a preparation method of the capsules. The preparation method includes the following steps: adding ethyl alcohol to radix ginseng rubra, salvia miltiorrhiza, angelicae sinensis, ligusticum chuanxiong and hawthorn for reflux extraction; filtering to obtain extracting solution and herb residue; concentrating the extracting solution to obtain extracting paste; mixing astragalus membranaceus with the herb residue, adding water for decoction, and filtering; concentrating the filtrate to obtain thick paste; drying the extracting paste and the thick paste, crushing and mixing to obtain fine powder X; taking and mixing leech, lumbricus and dragon's blood, crushing into fine powder Y; mixing the fine powder X and the fine powder Y uniformly, sieving, pelletizing and straightening; spraying an ethanol solution of borneol to prepare the capsules. The capsules provided by the invention can separate out the effective constituents of different raw medicinal materials to the maximum extent, effectively remain the active constituents, improve the drug efficacy and quickly reduce the symptom; the patient with coronary heart disease feels better on the following aspects: the angina pectoris symptom is alleviated, the electrocardiogram is improved, the Chinese medicinal syndrome is improved, hyperlipemia is alleviated, and the blood viscosity is reduced; the total effective rate reaches 89.8%, the long-term follow-up result is stable, and the capsules are free of toxic and side effects.

Description

【Technical field】 [0001] The invention belongs to the field of traditional Chinese medicines for treating cardiovascular and cerebrovascular diseases, and in particular relates to Kamailitong capsules for treating cardiovascular and cerebrovascular diseases and a preparation method thereof. 【Background technique】 [0002] Coronary heart disease and stroke are high-risk and frequently-occurring diseases worldwide, with a large number of patients; their pathological basis is also atherosclerotic lesions. Taking coronary heart disease as an example, according to epidemiological surveys and autopsy statistics, at least more than 30% of Chinese people over the age of 40 have coronary atherosclerosis. More than 600,000 people die from coronary heart disease every year in the United States; 260,000 to 390,000 people die every year in China (wherein more than 70% die outside the hospital due to untimely prevention and treatment). In China and East Asia, the incidence of coronary he...

Claims

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Application Information

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IPC IPC(8): A61K36/889A61K36/896A61K9/48A61P9/00A61P9/10A61P7/02A61K31/045A61K35/62
Inventor 郭冠英张毛珍
Owner 郭冠英
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