A method for removing EEG artifacts induced by transcranial magnetic stimulation of the brain

Abstract

A method for removing EEG artifacts induced by transcranial magnetic stimulation of the brain, using electric field simulation or electric field measurement, and by calibrating the method of generating an induced electric field by a magnetic stimulation coil, to determine the optimal position corresponding to the EEG acquisition device and the magnetic stimulation coil Optimal position to detect and obtain EEG signals. The present invention considers the relative position and angle of the EEG acquisition device and the stimulating coil when determining the brain stimulation area of ​​the transcranial magnetic stimulation, and gradually corrects the relative position of the wire and the coil by simulating or measuring the electric field strength and direction induced by the coil. EEG signals under TMS. It can remove most of the artifacts of EEG under TMS, make the EEG signal induced by TMS more accurate, reduce the side effects of TMS, and ensure its stimulation effect, fully reflect the role of TMS in the transmission of brain networks, and affect the EEG induced by TMS. Research is very important. The method can reduce the amplitude of artifacts by 10 to 20 times, and can reduce the duration of artifacts by 30%.

Description

technical field [0001] The invention relates to a method for acquiring electroencephalogram signals. In particular, it relates to a method for removing EEG artifacts induced by transcranial magnetic stimulation of the brain. Background technique [0002] Transcranial magnetic stimulation (TMS) technology is an important technical means in modern brain science research. Transcranial magnetic stimulation is a biostimulation technology that uses a time-varying magnetic field to act on the cerebral cortex to generate an induced current to change the action potential of the cortical nerve cells, thereby affecting the metabolism and neural electrical activity in the brain. It has many advantages such as painless, non-invasive, low risk, simple operation, repeatable stimulation, etc. It provides a new method and approach for the study of brain function network. [0003] The EEG signal collected on the human scalp is called scalp EEG (electroencephalography, EEG). EEG is a method...

AI Technical Summary

Problems solved by technology

Through the research, it is found that it is difficult to obtain EEG signals that simply reflect the mechanism of brain nerve activity within a few hundred milliseconds after TMS intervention, and there are generally serious artifacts, which means that each current pulse in the TMS coil produces The alternating magnetic field will cause the EEG electrodes near the stimulation site to record a high-amplitude and long-lasting TMS discharge artifact

This artifact can seriously affect the study of the EEG signal, while causing overload and saturation of the amplifier, damaging the amplifier

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