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Traditional Chinese medicine preparation for treating cerebral apoplexy

A traditional Chinese medicine preparation and cerebral apoplexy technology, which is applied in the field of traditional Chinese medicine preparations for the treatment of cerebral apoplexy, can solve the problems of increasing patient pain, patient side effects, weak symptomaticity and the like, and achieves the effects of low cost, high bioavailability and small dosage

Inactive Publication Date: 2015-12-30
王凯
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Traditional Chinese medicine lists cerebral apoplexy as the first of the four difficult diseases of "wind, tuberculosis, phlegm, and diaphragm". Some progress has also been made in the aspect of stroke. However, the traditional Chinese medicine prescriptions in the prior art lack dialectics, the treatment cycle is long, the symptomatology is not strong, the curative effect is not obvious, and even bring side effects to patients, which increases the pain of patients. Effective and safe drugs have become an important direction for clinical treatment of stroke

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0021] A traditional Chinese medicine preparation for treating cerebral apoplexy, which is prepared from the following raw materials in weight ratio:

[0022] 30 parts of loofah, 30 parts of capillary, 30 parts of frankincense, 30 parts of angelica, 25 parts of mulberry branch,

[0023] 25 parts of Citrus aurantium, 25 parts of Divine Comedy, 25 parts of Dandelion, 22 parts of Rhubarb, 22 parts of Atractylodes macrocephala,

[0024] 22 parts of Fangfeng, 20 parts of Chishao, 20 parts of Jujube, 20 parts of Chuanxiong, 20 parts of Bupleurum,

[0025] Nuxychnium 18 parts, Astragalus 18 parts, Chenpi 18 parts, Yuanbaocao 18 parts, Uncaria 15 parts,

[0026] Patrinia 15 parts, Lycium barbarum 12 parts, Plantain 12 parts, Achyranthes bidentata 10 parts, Guizhi 10 parts,

[0027] 8 parts of Polygonum multiflorum, 8 parts of Ginkgo biloba.

[0028] The preparation method of pharmaceutical preparation of the present invention is:

[0029] 1) Take each bulk drug according to the we...

Embodiment 2

[0034] A traditional Chinese medicine preparation for treating cerebral apoplexy, which is prepared from the following raw materials in weight ratio:

[0035] 35 parts of loofah, 35 parts of capillary, 35 parts of frankincense, 35 parts of angelica, 30 parts of mulberry branch,

[0036] 30 parts of Citrus aurantium, 30 parts of Divine Comedy, 30 parts of Dandelion, 25 parts of Rhubarb, 25 parts of Atractylodes macrocephala,

[0037] 25 parts of Fangfeng, 22 parts of Chishao, 22 parts of Jujube, 22 parts of Chuanxiong, 22 parts of Bupleurum,

[0038] Nuxychnium 20 parts, Astragalus 20 parts, Chenpi 20 parts, Yuanbaocao 20 parts, Uncaria 18 parts,

[0039] Patrinia 18 parts, Lycium barbarum 15 parts, Plantain 15 parts, Achyranthes bidentata 12 parts, Guizhi 12 parts,

[0040] 10 parts of Polygonum multiflorum, 10 parts of Ginkgo biloba.

[0041] The preparation method of pharmaceutical preparation of the present invention is:

[0042] 1) Take each bulk drug according to the ...

Embodiment 3

[0047]zoology experiment

[0048] 60 healthy Kunming strain mice, half male and half male, body weight 18.5 ± 2.0g, 60 mice were randomly divided into three groups, half male and half male, 20 in each group, which were respectively Example 1 group and Example 2 group , control group, control group is filled with normal water, embodiment 1-2 group is given the medicine of embodiment 1-2 respectively, and application mouse is carried out acute toxicity test and shows: compare with control group, mouse has no significant difference after administration , The experiment was continuously observed for two weeks, and the general condition, food intake, drinking water, and weight gain of the mice were all normal. On the day of administration and within two weeks after administration, no animal died, suggesting that the drug has low acute toxicity and is safe for clinical use.

[0049] long-term toxicity test

[0050] Select 60 SD rats, half male and half male. According to body wei...

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Abstract

The invention relates to a traditional Chinese medicine preparation for treating cerebral apoplexy. The traditional Chinese medicine preparation is prepared from the following raw materials: loofah sponge, oriental wormwood, frankincense, angelica sinensis, ramulus mori, immature bitter orange, medicated leaven, dandelion, rheum officinale, bighead atractylodes rhizome, divaricate saposhnikovia root, radix paeoniae rubra, Chinese dates, ligusticum wallichii, radix bupleuri, nux vomica, astragalus membranaceus, pericarpium citri reticulatae, hypericum sampsonii hance, uncaria rhynchophylla, herba patriniae, barbary wolfberry fruit, plantain herb, radix achyranthis bidentatae, cassia twigs, polygonum multiflorum and folium ginkgo. All the medicinal materials are combined to use and complement each other, and have a remarkable effect on the cerebral apoplexy and a broad application prospect.

Description

technical field [0001] The invention belongs to the technical field of traditional Chinese medicines, and in particular relates to a traditional Chinese medicine preparation for treating cerebral apoplexy. Background technique [0002] Cerebral apoplexy, also known as cerebral apoplexy, is a general term for acute cerebrovascular diseases in traditional Chinese medicine. It is a sudden onset cerebral blood circulation disorder. Refers to patients with cerebrovascular disease, due to various predisposing factors to cause cerebral artery stenosis, occlusion or rupture, resulting in acute cerebral blood circulation disorder, clinically manifested as symptoms and signs of transient or permanent brain dysfunction, An acute illness caused by a disorder of the blood vessels that carry blood to the brain. A stroke causes sudden damage to brain tissue, usually when a blood vessel that carries oxygen and other nutrients to the brain bursts or becomes blocked by a blood clot or other...

Claims

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Application Information

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IPC IPC(8): A61K36/815A61P9/10
Inventor 王凯
Owner 王凯
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