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Traditional Chinese medicine composition for treating primary hypertension

A technology of essential hypertension and composition, which is applied in the direction of drug combination, pharmaceutical formula, plant raw materials, etc., can solve the problems of insignificant effect and slow onset of effect, and achieve significant therapeutic effect, fast onset of effect, and convenient use Effect

Inactive Publication Date: 2015-12-30
QINGDAO HUAZHICAO PHARMA CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Antihypertensive drugs need long-term or life-long application, drug safety and patient tolerance are very important, traditional Chinese medicine treatment of high blood pressure drugs have few side effects and stable drug effect, can be used safely for a long time, and have broad prospects, but existing prevention and treatment of high blood pressure The existing traditional Chinese medicine has insignificant effect, slow onset and other deficiencies. It is of great significance for the clinical treatment of essential hypertension to seek a Chinese medicine composition with remarkable effect, fast onset and convenient taking.

Method used

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  • Traditional Chinese medicine composition for treating primary hypertension
  • Traditional Chinese medicine composition for treating primary hypertension
  • Traditional Chinese medicine composition for treating primary hypertension

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0026] Embodiment 1 of the present invention Chinese medicine composition granules are prepared from the following raw materials in parts by weight:

[0027] 20 parts of apocynum, 20 parts of Ophiopogon japonicus, 10 parts of Prunella vulgaris, 10 parts of capillary, 15 parts of Uncaria, 8 parts of jujube, 6 parts of Dendrobium, 5 parts of Panax notoginseng, 5 parts of herb, 10 parts of hawthorn and 5 parts of licorice .

[0028] The preparation method is as follows:

[0029] (1): Weigh Ophiopogon japonicus, crush it into a coarse powder, put it in a supercritical carbon dioxide extraction device, add 50% of the weight of the coarse powder and a 75% ethanol solution, adjust the flow rate of carbon dioxide to 18L / h, and the extraction pressure to be 18MPa, the extraction temperature is 50°C, the extraction time is 2h, and the Ophiopogon japonicus extract is obtained by decompression separation, and the Ophiopogon japonicus residue is retained;

[0030] (2): Weigh apocynum, Pr...

Embodiment 2

[0034]Embodiment 2 of the present invention Chinese medicine composition granules are prepared from the following raw materials in parts by weight:

[0035] 25 parts of Apocynum, 25 parts of Ophiopogon japonicus, 15 parts of Prunella vulgaris, 12 parts of capillary, 18 parts of Uncaria, 10 parts of jujube, 10 parts of dendrobium, 10 parts of Panax notoginseng, 8 parts of atractylodes, 12 parts of hawthorn and 10 parts of licorice .

[0036] The preparation method is the same as in Example 1.

Embodiment 3

[0038] Embodiment 3 of the present invention Chinese medicine composition tablet is prepared from the following raw materials in parts by weight:

[0039] 28 parts of apocynum, 30 parts of Ophiopogon japonicus, 20 parts of Prunella vulgaris, 15 parts of capillary, 20 parts of Uncaria, 12 parts of jujube, 15 parts of Dendrobium, 15 parts of Panax notoginseng, 12 parts of herb, 15 parts of hawthorn and 15 parts of licorice .

[0040] The preparation method is as follows:

[0041] (1): Weigh Ophiopogon japonicus, crush it into a coarse powder, place it in a supercritical carbon dioxide extraction device, add 75% ethanol solution with a volume fraction of 45% of the weight of the coarse powder, adjust the flow rate of carbon dioxide to 18L / h, and the extraction pressure to be 20MPa, the extraction temperature is 55°C, the extraction time is 2h, and the Ophiopogon japonicus extract is obtained by decompression separation, and the Ophiopogon japonicus residue is retained;

[0042]...

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Abstract

The invention discloses a traditional Chinese medicine composition for treating primary hypertension, and belongs to the technical field of traditional Chinese medicines. The composition is mainly prepared from the following raw materials: apocynum venetum, radix ophiopogonis, selfheal, capillary artemisia, uncaria rhynchophylla, Chinese date, dendrobe, pseudo-ginseng, rhizoma atractylodis, hawthorn and licorice root. The raw materials have a strong synergetic effect, so that the traditional Chinese medicine composition has a remarkable curative effect, stable drug property and small side effect when used for treating primary hypertension, and has a remarkable clinical popularization value.

Description

technical field [0001] The invention belongs to the technical field of traditional Chinese medicine, and in particular relates to a traditional Chinese medicine composition for treating essential hypertension. Background technique [0002] According to the WHO standard, the normal blood pressure of the human body is systolic blood pressure <140mmHg and diastolic blood pressure <90mmHg, beyond this range can be diagnosed as hypertension. Hypertension is a common cardiovascular disease, which is defined as a persistent increase in systemic arterial pressure. Hypertension secondary to kidney, endocrine and nervous system diseases is called secondary hypertension, accounting for 5%-10% of hypertensive patients; and hypertension whose cause has not been elucidated so far is called primary hypertension. hypertension. Essential hypertension accounts for more than 90% of hypertensive patients and is often accompanied by disorders of fat and glucose metabolism as well as hear...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/8984A61P9/12
Inventor 韦友红陈萍
Owner QINGDAO HUAZHICAO PHARMA CO LTD