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Environmental microorganism zygosaccharomyces bailii

A Bayer technology combining yeast and environmental microorganisms, applied in microorganisms, microorganism-based methods, biochemical equipment and methods, etc.

Inactive Publication Date: 2016-01-13
HANGZHOU HUQINGYUTANG PHARM CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Although clean technology can greatly reduce the risk of microbial contamination of food and drugs, it does not require an absolute sterile environment, nor can it prevent foreign microorganisms from invading processed materials and products

Method used

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  • Environmental microorganism zygosaccharomyces bailii
  • Environmental microorganism zygosaccharomyces bailii

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Embodiment Construction

[0011] The present invention will be further described below in conjunction with specific embodiments, but the protection scope of the present invention is not limited to this.

[0012] In the process of producing strong loquat lotion (Hangzhou), we observed that some samples contained yeast microorganisms, which brought major hidden dangers to the safety of medicines (such as causing bulging). In order to prevent pollution, we have found a stable contaminated bacteria and analyzed the genome information of the bacteria based on genome sequencing technology.

[0013] As shown in Figure 1, the process of the present invention is as follows:

[0014] (1) Microbial collection

[0015] Collect the microorganisms with tiger red and high salt fungus medium.

[0016] (2) Extraction of microbial genome

[0017] Resuspend the collected microorganisms in 0.5mL sterile PBS, add 50μL lyzosyme (lyzosyme, 10mg / mL), 6μL mutanolysin (mutanolysin, 25000U / mL; Sigma-Aldrich), 3μL lysostaphin (lysostaphin,...

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PUM

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Abstract

The invention discloses environmental microorganism zygosaccharomyces bailii. The environmental microorganism zygosaccharomyces bailii, which is discovered in a process of producing strong loquat syrup, is named zygosaccharomyces bailii HQ, and the environmental microorganism zygosaccharomyces bailii is preserved in China Center for Type Culture Collection on October 26, 2015 with preservation number of CCTCC NO: M2015641, in Wuhan University, Wuchang District, Wuhan, Hubei Province, postcode: 430072. The discovered novel pollutant strain is helpful for pharmaceutical enterprises to take an active effect in fights of attacking and defending pollution of the bacterium, so that microorganism pollution monitoring and controlling capacities are significantly improved.

Description

Technical field [0001] The invention relates to an environmental microorganism-Bayer combined yeast. Background technique [0002] Microorganisms are the most widely distributed and the largest number of organisms in nature. They are tiny, reproduce fast, and have strong adaptability. Some microorganisms invade the human body through the digestive tract, such as Salmonella, Vibrio parahaemolyticus, Listeria monocytogenes, etc. They can cause gastrointestinal diseases, and in severe cases can cause liver, brain, kidney damage, and even death. The harm of mold lies in the toxins it produces, such as aflatoxins and fumonisins. They are very toxic and have strong carcinogenicity. In addition, if microorganisms and pyrogens directly invade the human body through mucous membranes or blood vessels, they will cause more serious and direct harm to human health. Therefore, it is very important to prevent microbial contamination in the food and drug manufacturing process. Although clean...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): C12N1/16C12R1/645
Inventor 陈炜高岭张伟
Owner HANGZHOU HUQINGYUTANG PHARM CO LTD
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