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A kind of hip joint prosthesis and preparation method thereof

A technology of hip joint prosthesis and joint socket, applied in the direction of hip joints, prostheses, joint implants, etc., can solve the problems of human femoral stress shielding, poor biocompatibility, and short service life, so as to promote attachment growth and reduce The effect of absorbing and reducing secondary damage

Active Publication Date: 2017-11-28
TIANJIN MARVEL BIOTECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

[0005] The problem of the prior art that the present invention needs to solve is: the existing prosthesis used for hip joint transplantation is likely to cause stress shielding of the human femur, resulting in loosening, short service life, and poor biocompatibility, and secondary replacement will cause patient suffers more

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  • A kind of hip joint prosthesis and preparation method thereof
  • A kind of hip joint prosthesis and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0066] (1) Hip prosthesis

[0067] Embodiment 1 provides a kind of hip joint prosthesis, comprises acetabulum 1, femoral head 2, femoral neck 3, femoral stem 4 and collar plane 5, as figure 1 As shown, wherein the femoral stem 4 is provided with a hole-like structure, and the hole-like structure includes hole-like structures with different hole-like ranges, wherein the femoral head 2, the femoral neck 3 and the femoral stem 4 adopt It is made of titanium alloy material containing Nb, wherein, the outer surface and the inner surface of the femoral stem 4 are respectively provided with hydroxyapatite layers.

[0068] Wherein, the femoral stem is provided with a porous structure, and the area of ​​the porous structure accounts for 85% of the surface of the femoral stem. The porous structure is a large hole >100 μm, a medium hole of 10-100 μm, and a small hole <10 μm, Wherein the number of the macropore accounts for 10% of the total amount of the pore structure, the mesopore stru...

Embodiment 2

[0089] The difference between embodiment two and embodiment one is that the hip joint prosthesis in embodiment two does not include a collar plane, such as figure 2 As shown, wherein, the thickness of the hydroxyapatite layer on the inner and outer surfaces of the femoral stem is 40 μm. The acetabulum is made of aluminum oxide material, and the inside of the acetabulum is an aluminum oxide ceramic socket.

[0090] The femoral stem is provided with a hole-like structure, and the area of ​​the hole-like structure accounts for 83% of the surface of the femoral stem, wherein the number of the large holes accounts for 8% of the total amount of the hole-like structure, and the mesopore structure accounts for 83% of the total amount of the hole-like structure. 1% of the total structure, the number of the pores accounts for 91% of the total pore structure, and the corresponding Young's modulus is 46GPa.

[0091] Experimental results:

[0092] After cultivation, under the observation ...

Embodiment 3

[0094] The difference between the third embodiment and the first embodiment is that the thickness of the hydroxyapatite layer on the inner and outer surfaces of the femoral stem and the lower surface of the collar plane in the third embodiment is 60 μm.

[0095] Wherein, the femoral stem is provided with a hole-like structure, and the area of ​​the hole-like structure accounts for 75% of the surface of the femoral stem, wherein the number of the large holes accounts for 12% of the total number of the hole-like structures, and the mesopore structure accounts for 75% of the surface of the femoral stem. 3% of the total number of pore-like structures, and the number of small holes accounts for 85% of the total number of pore-like structures. The corresponding Young's modulus is 57 GPa.

[0096] Experimental results:

[0097] After cultivation, under the observation of the scanning electron microscope, the bone cell coverage rate of the whole prosthesis reached 45%, and the reticu...

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Abstract

The invention relates to the technical field of medical equipment, in particular to a hip prosthesis and a preparation method. The hip prosthesis comprises an acetabulum (1), a femur head (2), a femur neck (3) and a femur stem (4), wherein the femur stem (4) adopts porous structures with different pore diameter ranges; the femur head (2), the femur neck (3) and the femur stem (4) are made of a niobium-contained titanium alloy material; a hydroxyapatite layer is arranged on each of the outer surface and the inner surface of the femur stem (4). Through application of the hip prosthesis, the stress shielding for a human femur can be reduced; meanwhile, the service life of the hip prosthesis is prolonged, and the biocompatibility is improved.

Description

technical field [0001] The invention relates to the technical field of medical devices, in particular to a hip joint prosthesis and a preparation method. Background technique [0002] After nearly 30 years of development, hip replacement in China has been recognized as a very effective treatment for hip dysplasia and hip damage. By the end of 2014, the number of hip transplants worldwide had exceeded 500,000. Generally, the effective limb functional rehabilitation of domestic artificial hip joints can only last for about 10 years. The damage of artificial hip joints will indirectly cause patients to undergo secondary replacements and suffer more pain. At present, more than 75% of prostheses will fail due to the looseness of the femoral stem. The main reason for the failure of the graft is that the force of the human femur after transplantation is less than that of the femoral neck of the prosthesis, and bone tissue resorption occurs when the stress is less than 20 GPa, and w...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61F2/32A61L27/06A61L27/32A61L27/56A61L27/10
Inventor 刘鹏飞陈威潼韩雪姬晓兵
Owner TIANJIN MARVEL BIOTECH
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