Application of ribavirin in preparing medicine for treating ischemic cerebral apoplexy
A technology for treating ischemic stroke and drugs, applied in drug combinations, medical preparations containing active ingredients, sugar-coated pills, etc. Herpes, no pharmacological properties and other problems have been found to achieve the effect of improving the volume of brain tissue necrosis, expanding clinical indications, and highlighting the promotion prospect
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Embodiment 1
[0025] 1. Preparation of drugs
[0026] Take 50g of ribavirin and 2450g of starch, mix 950g of starch with water to make a thin slurry, then gradually add the remaining starch and all the ribavirin to the slurry under stirring, stir everything evenly to make granules, and then Sieve, dry, and pack into capsules.
[0027] 2. Selection of experimental objects
[0028] Randomly select 100 patients with onset time of more than 4.5 hours but less than 48 hours as experimental subjects, patients with large artery atherosclerosis and lacunar necrosis with necrosis volume exceeding 5ml, and without arrhythmia, macular edema, tumor and immunosuppression The patients who received the drug were used as the experimental subjects, and 100 people were matched with clinical and imaging characteristics as controls.
[0029] 3. Experimental method
[0030] The patients were divided into a ribavirin treatment group and a control group, the control group received standard ischemic stroke trea...
Embodiment 2
[0040] Take 50g of ribavirin and 2450g of starch, mix 950g of starch with water to make a thin slurry, then gradually add the remaining starch and all the ribavirin to the slurry under stirring, stir everything evenly to make granules, and then Sieve and dry to form granules.
Embodiment 3
[0042] Take 50g of ribavirin, 2300g of starch, and 150g of magnesium stearate, mix 950g of starch and water to make a thin slurry, and then gradually add the remaining starch, all of the ribavirin and all of the stearin to the slurry while stirring Magnesium acid, all stirred evenly, dried and compressed into tablets, film-coated to form tablets.
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