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Psoriasis treating medicine containing lysozyme

A technology of lysozyme and psoriasis, applied in the direction of drug combination, drug delivery, medical preparations containing active ingredients, etc., to achieve the effect of reasonable compatibility, better effect, and simple preparation method

Pending Publication Date: 2016-05-11
ZHEJIANG AEGIS BIOLOGICAL SCI & TECH CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0030] At present, the combination of lysozyme and danshensu for the prevention and treatment of psoriasis has not been reported

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0045] Embodiment 1, prepare the ointment containing Danshensu

[0046] Weigh 10 parts by weight of Danshensu, 50 parts by weight of sodium carboxymethyl cellulose, 10 parts by weight of zinc oxide and 1 part by weight of disodium edetate and disperse them in 500 parts by weight of purified water, and stir to obtain water phase; then weigh 50 parts by weight of vaseline, put 10 parts by weight of Tween 80 in another container, and mix to obtain an oil phase; heat the water phase and the oil phase respectively, mix them, homogenize for 10 minutes, and prepare into ointment A1 containing Danshensu.

Embodiment 2

[0047] Embodiment 2, prepare the ointment containing lysozyme

[0048] Weigh 10 parts by weight of lysozyme, 50 parts by weight of sodium carboxymethylcellulose, 10 parts by weight of zinc oxide and 1 part by weight of disodium ethylenediamine tetraacetate and disperse them in 500 parts by weight of purified water, and stir to obtain water phase; then weigh 50 parts by weight of vaseline, put 10 parts by weight of Tween 80 in another container, and mix to obtain an oil phase; heat the water phase and the oil phase respectively, mix them, homogenize for 10 minutes, and prepare into ointment A2 containing lysozyme.

Embodiment 3

[0049] Embodiment 3, preparation contains the ointment of lysozyme and Danshensu (1:1)

[0050] Weigh 5 parts by weight of lysozyme, 5 parts by weight of Danshensu, 50 parts by weight of sodium carboxymethylcellulose, 10 parts by weight of zinc oxide and 1 part by weight of disodium edetate dispersed in 500 parts by weight In purified water, stir evenly to obtain the water phase; then weigh 50 parts by weight of vaseline, and put 10 parts by weight of Tween 80 in another container, and mix to obtain the oil phase; heat the water phase and the oil phase respectively and mix them, After 10 minutes of qualitative transformation, the ointment A3 containing lysozyme and danshensu (1:1 by weight) was made after cooling down.

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Abstract

The invention relates to psoriasis treating medicine containing lysozyme, wherein a weight ratio of active components lysozyme to tanshinol is (1:10) to (10:1). Compared with common western medicine, the psoriasis treating medicine containing lysozyme is simple in preparing method and reasonable in compatibility of medicine, the two active components can generate synergistic interaction while exerting respective effects, and psoriasis is obviously treated. The lysozyme and tanshinol come from the nature, are safe, non-toxic and have no side effects; since the medicine composition has no western medicine components, the medicine has no drug resistance.

Description

technical field [0001] The invention relates to the field of pharmacy, in particular to a medicine for treating psoriasis. Background technique [0002] Psoriasis, also known as psoriasis, is a skin disease mainly characterized by scales and erythema, accompanied by certain itching. Psoriasis is non-infectious, but has a high incidence rate, long course of disease, and is easy to relapse, stubborn and difficult to cure. It has a great impact on the patient's physical health and spirit. It has the title of "undead cancer" in dermatology. [0003] The etiology of psoriasis is still unclear. Modern studies believe that it is related to factors such as genetics, infection, immunity, spirit, endocrine, trauma, diet and metabolic disorders. At present, it is believed that immune mediation is the main mechanism of occurrence. Its clinical manifestations are erythematous and scaly lesions, with erythematous papules at the beginning, the epidermis is covered with layers of silvery w...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K38/47A61P17/06A61K31/192A61K36/537A61K35/57
CPCA61K38/47A61K9/0014A61K9/06A61K31/192A61K35/57A61K36/537A61K47/38
Inventor 潘宏涛卢亚萍
Owner ZHEJIANG AEGIS BIOLOGICAL SCI & TECH CO LTD