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Traditional Chinese medicine composition with antibacterial and anti-inflammation effects and preparation method of composition

An antibacterial, anti-inflammatory and composition technology, which is applied in the direction of antibacterial drugs, drug combinations, anti-inflammatory agents, etc., can solve the problems of use time dependence, drug resistance, and large side effects of antibiotics, and achieve safe use and significant anti-inflammatory and anti-bacterial effects Effect

Inactive Publication Date: 2016-07-13
NORTH CHINA UNIVERSITY OF SCIENCE AND TECHNOLOGY
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] When Western medicine treats inflammation, antibiotics are usually used. Antibiotics have large side effects, and they are prone to dependence and drug resistance if used for a long time

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0028] S1. Take 50 parts of fresh lemons, put them in the enzymatic hydrolysis tank, add the compound enzymatic hydrolysis solution at a rate of 300 g / ton, and conduct enzymatic hydrolysis for 72 hours at 25°C, stir and oxygenate once every 4 hours, and control the pH value at 3.5 After the enzymolysis is finished, inoculate the microbial starter according to the ratio of 1.5% of the inoculum, keep the temperature at 35°C, ferment for 53 hours, dry at low temperature after the fermentation, grind it into fine powder, and obtain lemon fermentation powder;

[0029] S2. Take the dried olive leaves and process them with a flash extractor. The obtained extract is first heated with strong fire, then heated with a slow fire for 1 hour after boiling, and then filtered with a hollow fiber ultrafiltration membrane; Membrane filtration, combined three filtrates, concentrated to 1.5g / ml, to obtain olive leaf extract;

[0030] S3, take the cleaned red jujube leaves and place them in the st...

Embodiment 2

[0036] S1. Take 70 parts of fresh lemons, put them in the enzymatic hydrolysis tank, add the compound enzymatic hydrolysis solution at a ratio of 350 g / ton, and conduct enzymatic hydrolysis for 72 hours at 35°C, stir and oxygenate once every 4 hours, and control the pH value at 6.2 After the enzymolysis is finished, inoculate the microbial starter according to the ratio of 1.5% of the inoculation amount, keep the temperature at 41° C., ferment for 53 hours, dry at low temperature after the fermentation is finished, grind into fine powder, and obtain lemon fermentation powder;

[0037] S2, take the dried olive leaves and process them with a flash extractor. The obtained extract is first heated with a strong fire, and then heated with a slow fire for 1.8h after boiling, and then filtered with a hollow fiber ultrafiltration membrane; Membrane filtration, combined three filtrates, concentrated to 1.5g / ml, to obtain olive leaf extract;

[0038]S3, take the washed red jujube leaves ...

Embodiment 3

[0044] S1. Take 60 parts of fresh lemons, put them in the enzymatic hydrolysis tank, add the compound enzymatic hydrolysis solution at a ratio of 325 g / ton, and conduct enzymolysis for 72 hours at 30°C, stir and oxygenate once every 4 hours, and control the pH value at 4.85 After the enzymolysis is finished, inoculate the microbial starter according to the ratio of 1.5% of the inoculum, keep the temperature at 38°C, ferment for 53 hours, dry at low temperature after the fermentation, grind it into fine powder, and obtain lemon fermentation powder;

[0045] S2, take the dried olive leaves and process them with a flash extractor. The obtained extract is first heated with a strong fire, heated with a slow fire for 1.4h after boiling, and filtered with a hollow fiber ultrafiltration membrane; Membrane filtration, combined three filtrates, concentrated to 1.5g / ml, to obtain olive leaf extract;

[0046] S3, take the washed red jujube leaves and place them in the steam explosion tank...

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PUM

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Abstract

The invention discloses traditional Chinese medicine composition with antibacterial and anti-inflammation effects and a preparation method of the composition. The traditional Chinese medicine composition is prepared from 5-15 parts of Rumex crispus, 10-15 parts of dandelions, 5-10 parts of original aloe juice, 3-7 parts of lemon ferment powder, 6-10 parts of pine needle powder, 3-15 parts of common cnidium fruits, 3-17 parts of caulis lonicerae, 3-10 parts of an olive leaf extract, 5-10 parts of a red date leaf extract, 6-10 parts of a milk thistle extract, 4-10 parts of a cranberry extract and 10-15 parts of a rosin derivative which is acrylpimaric acid(2-p-nitrophenyl)thiadiazole. A special technology is adopted, multiple effective ingredients are obtained, and the scientific ratio is adopted, so that the obtained composition has significant antibacterial and anti-inflammation effects and is safe to use and free of side effects.

Description

Technical field [0001] The present invention relates to the field of pharmaceutical preparation, and specifically relates to an antibacterial and anti-inflammatory Chinese medicinal composition and a preparation method thereof. Background technique [0002] Inflammation is a very common and important basic pathological process. Traumatic infections on the body surface and most common and frequently-occurring diseases of various organs (such as boils, carbuncles, pneumonia, hepatitis, nephritis, etc.) are inflammatory diseases. The defensive response of living tissues with vascular systems to damaging factors is called inflammation. [0003] Vascular responses are central to the inflammatory process. Inflammation, what people usually call "inflammation", is a defensive response of the body to stimulation, which manifests as redness, swelling, heat, pain and dysfunction. Inflammation can be infectious inflammation caused by infection or non-infectious inflammation not caused...

Claims

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Application Information

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IPC IPC(8): A61K36/886A61K36/896A61P31/04A61P29/00A61K31/433
CPCA61K36/70A61K31/433A61K36/15A61K36/234A61K36/28A61K36/288A61K36/32A61K36/355A61K36/45A61K36/725A61K36/752A61K36/886A61K36/896A61K2236/19A61K2236/33A61K2236/331A61K2236/39A61K2236/51A61K2236/53A61K2300/00
Inventor 张文丽耿福李旗秦丽娟李倩刘国荣朱莹张文杰刘倩
Owner NORTH CHINA UNIVERSITY OF SCIENCE AND TECHNOLOGY
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