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Medical rhinitis antibacterial agent and preparation method thereof

An antibacterial agent and rhinitis technology, applied in the field of medical rhinitis antibacterial agent and its preparation, can solve the problems of local tissue destruction in the nose, body fluid retention in patients, and induction of drug-induced rhinitis, etc., to inhibit and prevent bacterial infection, broad-spectrum Bacteriostatic, pain-reducing effects

Inactive Publication Date: 2016-07-20
DONGGUAN DAQING MEDICAL DEVICES CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, taking anti-inflammatory drugs, antibiotics, nasal drops and other rhinitis drugs can alleviate and reduce the symptoms of chronic rhinitis to a certain extent, but if patients abuse hormones and antibiotic rhinitis drugs for a long time to treat chronic rhinitis, it will cause chronic rhinitis. Fluid retention occurs in the patient's body, and at the same time, the bacteria continuously mutate and become resistant to drugs, which induces more serious rhinitis such as drug-induced rhinitis and atrophic rhinitis
[0005] 2. Surgical treatment: The traditional surgical treatment of rhinitis includes cryotherapy, laser, microwave, radio frequency and other surgical treatment methods, but these physical treatment methods are generally only suitable for hyperplastic lesions, and the long-term effect is uncertain. Organizations are also destructive

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0046] A medical rhinitis antibacterial agent is prepared from the following raw materials in parts by weight:

[0047] Small molecule chitosan quaternary ammonium salt 0.1g

[0048] Physiological sea water 0.1g

[0049] Chinese medicine extract 97g,

[0050] The Chinese medicine extract is prepared by extracting the following Chinese medicine raw materials in parts by weight:

[0051] Goose does not eat grass 50g, angelica dahurica 5g, asarum 5g, magnolia 9g, wormwood 6g, grape seed 8g, star anise 6g, camellia seed 8g.

[0052] A preparation method of medical rhinitis antibacterial agent comprises the following steps:

[0053] (1) Weigh all the raw materials of traditional Chinese medicine by weight, add distilled water equivalent to 10 times the total weight of the medicinal materials, soak for 1 hour, heat and extract, extract for the first time for 2 hours, add water for the second time equivalent to 5 times the total weight of the medicinal materials, and extract For ...

Embodiment 2

[0057] A medical rhinitis antibacterial agent is prepared from the following raw materials in parts by weight:

[0058] Small molecule chitosan quaternary ammonium salt 15g

[0059] Physiological sea water 10g

[0060] Chinese medicine extract 1g,

[0061] The Chinese medicine extract is prepared by extracting the following Chinese medicine raw materials in parts by weight:

[0062] Goose does not eat grass 1g, angelica 1g, asarum 1g, magnolia 1g, wormwood 1g, grape seed 1g, star anise 1g, camellia seed 1g.

[0063] A preparation method of medical rhinitis antibacterial agent comprises the following steps:

[0064] (1) Weigh all the raw materials of traditional Chinese medicine by weight, add distilled water equivalent to 5 times the total weight of the medicinal materials, soak for 2 hours, heat and extract for 1 hour, add water equivalent to 8 times the total weight of the medicinal materials for the second time, extract for 60 minutes, and extract for the third time The...

Embodiment 3

[0068] A medical rhinitis antibacterial agent is prepared from the following raw materials in parts by weight:

[0069] Small molecule chitosan quaternary ammonium salt 50g

[0070] Physiological sea water 80g

[0071] Chinese medicine extract 700g,

[0072] The Chinese medicine extract is prepared by extracting the following Chinese medicine raw materials in parts by weight:

[0073] Goose does not eat grass 200g, angelica dahurica 30g, asarum 30g, magnolia 50g, wormwood 40g, grape seeds 50g, star anise 40g, camellia seeds 50g.

[0074] A preparation method of medical rhinitis antibacterial agent comprises the following steps:

[0075] (1) Weigh all the raw materials of traditional Chinese medicine by weight, add distilled water equivalent to 6 times the total weight of the medicinal materials, soak for 1.5 hours, heat and extract for 1.5 hours, add water for the second time equivalent to 6 times the total weight of the medicinal materials, and extract for 45 minutes. The...

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Abstract

The invention relates to a medical rhinitis antibacterial agent and a preparation method thereof. The antibacterial agent is prepared from small-molecule chitosan quaternary ammonium salt, physiological sea water and traditional Chinese medicine extract, wherein the traditional Chinese medicine extract is obtained by extracting centipede minima, Angelica dahurica, asarum, biond magnolia flowers, artemisia argyi, seeds of Vitis vinifera L., illicium verum and camellia seeds in water. The antibacterial agent has high bactericidal performance as well as good biocompatibility and broad-spectrum bacteria resistance at the same time, can inhibit and prevent tissue on the nasal mucosa or under the nasal mucosa from being infected by germs, repair injured tissue and relieve pains, has good adjunctive treatment and preventing effects on symptoms such as allergic rhinitis, acute or chronic rhinitis, as well as nasal obstruction, rhinalgia, nasal dryness and pruritus, rhinorrhea, nasosinusitis and the like of rihinitis, takes effect rapidly and is free of side effects; rhinitis cannot easily relapse, and the preparation method is simple.

Description

technical field [0001] The invention relates to the field of medical antibacterial agents, in particular to a medical rhinitis antibacterial agent and a preparation method thereof. Background technique [0002] Rhinitis is one of the common and frequently-occurring nasal diseases. Patients often show symptoms such as nasal congestion, runny nose, headache, memory loss, and lack of energy, which seriously affect patients' daily life, work and study. Delayed treatment can easily induce complications such as sinusitis, pharyngitis, and otitis media, and patients need to be treated as soon as possible. [0003] Traditional treatments for rhinitis include: [0004] 1. Drug treatment: Intranasal glucocorticoids are the first choice for rhinitis, have good anti-inflammatory effects, and eventually produce decongestant effects. However, taking anti-inflammatory drugs, antibiotics, nasal drops and other rhinitis drugs can relieve and reduce the symptoms of chronic rhinitis to a cer...

Claims

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Application Information

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IPC IPC(8): A61K36/87A61P11/02A61P37/08A61P31/02A61P31/04A61K31/722A61K33/00
CPCA61K36/28A61K31/722A61K33/00A61K36/232A61K36/268A61K36/282A61K36/57A61K36/575A61K36/82A61K36/87A61K2236/331A61K2236/39A61K2300/00
Inventor 滕永慧李丽瑛梁奕福
Owner DONGGUAN DAQING MEDICAL DEVICES CO LTD
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