The invention relates to a process for advanced treatment of antibiotic waste water. The process is used for further treating the waste water obtained after secondary sedimentation tank treatment during the treatment of the antibiotic waste water, and comprises the following steps: firstly, performing ultrafiltration treatment on the waste water, which is obtained after the secondary sedimentation tank treatment, in an ultrafiltration apparatus so as to filter out macromolecular particulate matters in the waste water, thereby obtaining a concentrated solution and a filtrate; and then, performing degradation treatment on the concentrated solution in an aerobic biological treatment system, delivering the concentrated solution after the degradation treatment in the aerobic biological treatment system into a secondary sedimentation tank, and treating the filtrate by a series of treatment steps of regulation, air flotation, sand filtration, catalytic oxidation, sterilization and detection to obtain recycled water which accords with a recycled water standard. The process provided by the invention combines a chemical treatment method, a physical treatment method and a membrane treatment method together, and has the advantages of short process route, good treatment effect, small produced sludge amount, low system energy consumption, low equipment operating cost, simple operation and small labor intensity.