Liquid bandage used in field

Abstract

The invention discloses a liquid bandage used in field. The liquid bandage used in field comprises chitosan, cellulose acetate, bullfrog antibacterial peptide, polyvinyl alcohol, polyvinylpyrrolidone, ovalbumin and glycerin. A preparation method of the field liquid bandage comprises dissolving the bullfrog antibacterial peptide in a protein solution with content of 6% to obtain a chitosan-acetic acid solution with content of 2%, taking polyvinyl alcohol and polyvinylpyrrolidone, uniformly stirring the polyvinyl alcohol and polyvinylpyrrolidone, dissolving the mixture in injection water according to a W / V ratio of 1.0-1.5: 100 to obtain a solution, dissolving cellulose acetate in a solvent, carrying out magnetic stirring to obtain a uniform solution, blending the above solutions, dropwisely adding a glycerinum solution into the mixed solutions and adjusting pH to 5.5-6.8 so that the liquid bandage is obtained. The liquid bandage used in field has a reasonable formula. The bullfrog antibacterial peptide has effects of antibiosis, haemostasis and ovalbumin crosslinking reaction promotion and improves a film forming rate. Cellulose acetate is a film forming material and a good slow release material and improves bullfrog antibacterial peptide use effects.

Description

technical field [0001] The invention belongs to the technical field of liquid bandages, and in particular relates to a liquid bandage for field use. technical background [0002] With the acceleration of the pace of society, people's activities increase, so the number of injured people increases year by year. Therefore, the demand for bandages in daily life is very large, and the demand is even greater in wartime. There are about 60,000 hospitals of different sizes in my country at present, and bandages are needed to treat trauma patients in these hospitals. According to incomplete statistics, about tens of thousands of tons of cotton yarn are used for bandages in my country every year. The number of patients who did not go to the hospital after being injured cannot be counted at present. If these people are added up, the demand is huge. It is also estimated that the annual consumption of single-function "Band-Aids" is about 250 million pieces. From these circumstances, t...

AI Technical Summary

Problems solved by technology

Gauze acts as a support and has the function of absorbing wound exudate; the rubber adhesive adheres to the skin surface to fix it; the effective drug ingredients have the functions of antibacterial, anti-inflammatory and hemostasis, but its field application has certain limitations Non-toxic, not easy to store, easy to be polluted, the band-aid self-adhesive backing paper will pollute the environment, and it will also affect the appearance when used. There are a lot of traditional Chinese medicine liquid bandages, but the smell of Chinese medicine is strong, and it is not easy to be accepted by the public.

[0004] In the existing prior art about liquid bandages being used for abrasions, cuts, mild burns, surgical wounds, etc., most of them exist in the form of sprays or spray gels, although the products of this dosage form have Simple and convenient to use, fast film forming speed, waterproof and reducing scar formation, but there are also disadvantages such as easy blockage of the spray port, aerosol propellant harmful to the human body or polluting the environment, difficulty in controlling the thickness of the spray film, and poor durability of the effect.

More importantly, the existing liquid bandages still have unsatisfactory hemostatic and bactericidal effects. Therefore, it is necessary to find a cost-effective liquid bandage that is used in the field, has good hemostatic and bactericidal effects, and has no side effects. of