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Novel material applied to indwelling needle catheter and preparation method thereof

A new type of material and indwelling needle technology, applied in the field of polymer materials, can solve problems such as high adsorption force, difficulty in satisfying patients, and infection

Inactive Publication Date: 2016-07-27
SUZHOU LINHWA MEDICAL DEVICES CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, the surface of ordinary medical polyurethane elastomers is not smooth enough, the adsorption force is high, and residues are easy to adhere to, causing infection, or aggravating the pain of patients
In addition, ordinary medical polyurethane elastomers do not have good antibacterial properties, and it is difficult to meet the needs of patients

Method used

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  • Novel material applied to indwelling needle catheter and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

preparation example Construction

[0052] (1) Preparation of oligomeric chitosan grafted piperazine diketo acid

[0053] In a 100ml three-neck bottle, add 5g of chitosan oligosaccharides with a weight average molecular weight of 20,000, 5ml of glacial acetic acid, and 10ml of hydrogen peroxide solution with a mass concentration of 5%, stir, completely dissolve, and keep warm at 55°C for 5h; After the reaction, add 2ml methanol, 0.004g piperazine diketo acid and 0.014g piperazine diketone sulfonic acid, stir and react at room temperature for 12h to obtain a reaction solution; use 10wt% NaOH solution to adjust the pH of the reaction solution to neutral , filtered, soaked in 20ml of acetone for 10h, washed with 5ml of acetone, filtered, and dried under reduced pressure at 40°C for 12h;

[0054] (2) Grafting quaternary ammonium salts on chitosan oligosaccharides modified with piperazinone diacid

[0055] In a 100ml three-necked flask, add 0.1mol of 1,12-dibromododecane, 0.016mol of N-methylimidazole, 0.011mol of p...

Embodiment 1

[0106] 100 parts by weight of A1 and 10 parts by weight of B1 were stirred evenly by a mixer at room temperature;

[0107] The uniformly stirred material is fed into a twin-screw extruder and heated to 200°C for extrusion molding.

Embodiment 2

[0109] 100 parts by weight of A1 and 30 parts by weight of B1 were stirred evenly by a mixer at room temperature;

[0110] The uniformly stirred material is fed into a twin-screw extruder and heated to 200°C for extrusion molding.

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Abstract

The invention discloses a novel material applied to an indwelling needle catheter. The raw materials for preparing the material comprise activated medical-grade PU and carboxylated polytetrafluoroethylene. The invention also discloses a preparation method of the novel material applied to the indwelling needle catheter. The novel material applied to the indwelling needle catheter has the advantages of extremely smooth surface, extremely low adhesion force, excellent human body compatibility, antibacterial property and the like.

Description

technical field [0001] The invention belongs to the technical field of polymer materials, and more specifically, the invention relates to a novel polymer material used for indwelling needle catheters and a preparation method thereof. Background technique [0002] Indwelling needles are widely used in clinical medicine, which can reduce the pain caused by repeated venipuncture and the fear of injections, relieve the patient's anxiety, facilitate clinical medication, rescue medication for acute and critical patients, and reduce the work of nurses The quantity, the length of the indwelling needle indwelling time and the comfort of the patient have become the most concerned issues, and they are also the symbol of the successful use of the indwelling needle and the premise of promotion. In the prior art, the preparation of indwelling needle catheter generally uses medical polyurethane elastomer, which has good extensibility and flexural resistance, high strength, good biocompat...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): C08L75/04C08L27/18C08L5/08C08L79/04C08K5/06C08B37/08
CPCC08L75/04C08B37/003C08L2203/02C08L2205/03C08L2205/035C08L27/18C08L5/08C08L79/04C08K5/06
Inventor 吴林元俞云龙吴以照
Owner SUZHOU LINHWA MEDICAL DEVICES CO LTD
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