Composition containing salvia miltiorrhiza fat soluble ingredients and coenzyme Q10, preparation method of composition and drug containing composition

A technology of fat-soluble and composition, which is applied to the medicine for treating and preventing cardiovascular and cerebrovascular diseases and vascular dementia, the composition containing the fat-soluble components of Danshen and coenzyme Q10 and its preparation field, which can solve the undiscovered vascular dementia to improve aortic atherosclerosis and cognitive dysfunction, repair vascular endothelial cells, and reduce activation

Inactive Publication Date: 2016-08-24
程凤森
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  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

[0004] However, the application of the formula or composition of the fat-soluble components of Danshen combined with coenzyme Q10 in the prevention and treatment of cardiovascular disease and secondary vascular dementia has not been found so far.

Method used

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  • Composition containing salvia miltiorrhiza fat soluble ingredients and coenzyme Q10, preparation method of composition and drug containing composition
  • Composition containing salvia miltiorrhiza fat soluble ingredients and coenzyme Q10, preparation method of composition and drug containing composition
  • Composition containing salvia miltiorrhiza fat soluble ingredients and coenzyme Q10, preparation method of composition and drug containing composition

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Embodiment Construction

[0025] The composition containing the fat-soluble components of Salvia Miltiorrhiza and coenzyme Q10 of the present invention comprises the following components in weight percentage: 24% of the fat-soluble components of Salvia Miltiorrhiza, 23% of coenzyme Q10, 3% of vitamin K and 50% of corn oil.

[0026] The content of tanshinone IIA, the main effective substance in 9 batches of Danshen fat-soluble components measured by HPLC, ranges from 18% to 42%.

[0027] The preparation method of the composition containing the fat-soluble components of Salvia Miltiorrhiza and coenzyme Q10 is as follows: take 240 mL of the fat-soluble components of Salvia Miltiorrhiza, and add 230 g of coenzyme Q10 and 30 g of vitamin K to it in proportion, stir to make it dissolve evenly, and then add 500 mL of corn oil, and finally bring the total composition volume to 1000 mL.

[0028] Wherein, the preparation method of the fat-soluble components of Salvia miltiorrhiza includes the following steps: ta...

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Abstract

The invention discloses composition containing salvia miltiorrhiza fat soluble ingredients and coenzyme Q10, a preparation method of the composition and a drug containing the composition. The composition is prepared from components in percentage by weight as follows: 8%-24% of the salvia miltiorrhiza fat soluble ingredients, 16%-23% of the coenzyme Q10, 1.2%-3% of vitamin K and 50%-74% of corn oil. The composition can correct lipid metabolism unbalance of a body, reduce generation of lipid peroxide and reduce activation of inflammatory factors, so that atherosclerosis of aorta and cognitive impairment are relieved, and the composition has the efficacy of relieving disturbance of lipid metabolism, promoting antioxidation, relaxing vascular smooth muscles, repairing vascular endothelial cells and preventing nerve cell injury caused by ischemia and hypoxia; besides, the composition is used for preparing the drug and can effectively prevent or/and treat cardiovascular diseases and vascular dementia.

Description

technical field [0001] The invention relates to a composition, which belongs to the technical field of medicines, in particular to a composition containing salvia miltiorrhiza and coenzyme Q10, a preparation method thereof and a medicine for treating and preventing cardiovascular and cerebrovascular diseases and Drugs for vascular dementia. Background technique [0002] Cardiovascular disease and the resulting vascular dementia pose a serious threat to the health and quality of life of the elderly. Atherosclerosis, from hyperlipidemia and hypercholesterolemia to fat deposition, is considered to be the cause of pulmonary disease. Key factor in heart attack and vascular dementia. [0003] Salvia miltiorrhiza, as a traditional medicine with the same origin as food, has been used for a long time in the prevention and treatment of cardiovascular and cerebrovascular. Modern pharmacological research has further found that the main component of the fat-soluble active ingredient of...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/537A61P9/10A61P9/00A61P25/00A61K31/122
CPCA61K31/122A61K36/537A61K2236/333A61K2300/00
Inventor 程凤森梁美华
Owner 程凤森
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