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Traditional Chinese medicine composition for treating soft tissue injuries and preparation method thereof

A soft tissue injury and composition technology, which is applied in the direction of drug combinations, pharmaceutical formulas, active ingredients of hydroxyl compounds, etc., can solve the problems of unobserved curative effect, unfavorable drug promotion, unclear focus targets, etc., and achieve stable quality and simple drug taste Effect

Inactive Publication Date: 2016-09-21
SOUTH CHINA NORMAL UNIVERSITY
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, at present, most of the prescriptions have a variety of medicinal flavors, resulting in unclear targets for lesions; and most of them are hospital preparations, ancestral prescriptions, experience prescriptions, etc., and the curative effect remains to be seen, which is not conducive to the promotion of drugs

Method used

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  • Traditional Chinese medicine composition for treating soft tissue injuries and preparation method thereof
  • Traditional Chinese medicine composition for treating soft tissue injuries and preparation method thereof
  • Traditional Chinese medicine composition for treating soft tissue injuries and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0036] According to the following description, weigh the raw materials of Chinese medicinal materials: Gardenia 800g, Chonglou 600g, Chuanxiong 200g, Borneolum 68g, Menthol 72g.

[0037] Step 1: Take the prescribed amount of Ligusticum chuanxiong, crush it into a coarse powder, add 6 times the amount of water, soak for 1 hour, and distill for 5 hours to extract the volatile oil.

[0038] Step 2: Take the prescribed amount of gardenia, crush it, add the decoction pieces of Chonglou and the above-mentioned medicinal residue of Chuanxiong, add water to decoct 3 times, each time 12 times the amount of water, decoct for 1.5 hours each time, soak before the first decoction After 2.0 hours, filter, discard the medicinal residues, place the medicinal solution overnight, filter, combine the medicinal solution obtained from the extraction of volatile oil from Rhizoma Chuanxiong, mix well, concentrate under reduced pressure to a relative density of 1.10-1.12 (30°C), and set aside.

[0039]...

Embodiment 2

[0044] The preparation method of Example 2 is the same as that of Example 1, the difference being that the raw materials are composed of: 600g of gardenia, 500g of Rhizoma chinensis, 100g of Chuanxiong, 65g of borneol, and 68g of menthol.

Embodiment 3

[0046] The preparation method of embodiment 3 is the same as that of embodiment 1, the difference is that the composition of its raw materials is: gardenia 700g, polyphylla 700g, chuanxiong 300g, borneol 72g, menthol 76g.

[0047] 【Efficacy analysis】

[0048] Refer to "Chinese Medicine Pharmacological Research Methodology" and related literature. Formulate the following experiments to prove that this Chinese medicine has a significant inhibitory effect on inflammation, soreness, swelling and pain caused by acute and chronic soft tissue injuries, osteoarthropathy and other diseases.

[0049] 1 Effect of Chongzhi Zhitong Ointment on Cotton Ball Granuloma

[0050] Abstract The effect of Chongzhi Zhentong ointment on cotton ball granuloma in rats was observed experimentally. The results showed that the wet weight and dry weight of the granuloma in the Chongzhi Zhentong Ointment Group Example 1, Example 2, and Example 3 were significantly lighter than those of the control group. ...

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Abstract

The invention provides a traditional Chinese medicine composition for treating soft tissue injuries. The traditional Chinese medicine composition is prepared from, by weight, 600-900 parts of fructus gardenia, 500-700 parts of Paris polyphylla, 100-300 parts of the rhizome of chuanxiong, 65-72 parts of borneol and 68-76 parts of menthol. The traditional Chinese medicine composition has a remarkable treatment effect on acute and chronic soft tissue injuries, osteoarthritis and other diseases, an obvious treatment effect is achieved for traumatic injuries and limb pain, and the traditional Chinese medicine composition is stable in quality, controllable and free of toxins. Experimental study shows that the traditional Chinese medicine composition has a remarkable inhibition effect on inflammation, aching expanding and swelling pain caused by the soft tissue injuries. The full formula of the traditional Chinese medicine composition focuses on etiology and pathogenesis of acute and chronic soft tissue injuries and osteoarthritis, all the medicine is in reasonable compatibility, and the effects of clearing away heat and toxic materials, eliminating stasis to subdue swelling and promoting blood circulation to arrest pain are achieved. The medicine flavor is simple, and the traditional Chinese medicine composition can effectively treat acute and chronic soft tissue injuries, osteoarthritis and other diseases.

Description

technical field [0001] The invention belongs to the field of traditional Chinese medicine preparations, and specifically discloses a traditional Chinese medicine composition for treating soft tissue injuries and a preparation method thereof. Background technique [0002] Soft tissue injury refers to the skin, subcutaneous superficial and deep fascia, muscle, tendon, tendon sheath, ligament, joint capsule, synovial bursa, intervertebral disc, peripheral neurovascular and other tissues of the human body caused by various acute trauma or chronic strain, as well as its own disease pathology. The pathological damage of the body is called soft tissue injury, and traditional Chinese medicine is called tendon injury. Clinical manifestations: pain, swelling, deformity, dysfunction. Starting from the overall concept, Chinese medicine believes that tendons and bones, viscera, meridians, qi and blood are interrelated and inseparable. Therefore, although tendon injuries are external, th...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/896A61P19/04A61P19/02A61P29/00A61K31/045
CPCA61K31/045A61K36/236A61K36/744A61K36/896A61K2236/331A61K2236/39A61K2236/51A61K2236/53A61K2300/00
Inventor 张鹤鸣武建忠白虎成李锦怀黄迎洁柯志意张志祥
Owner SOUTH CHINA NORMAL UNIVERSITY
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