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Chinese lobelia freshly-squeezed freeze drying powder decoction tablets and preparation process thereof

A technology of dry powder and preparation process, which is applied in the field of processing technology of Chinese medicine Lobelia decoction pieces, can solve the problems of time-consuming and energy consumption, large loss of effective components, difficulty in extracting non-polar effective components, etc. Storage and transportation and clinical adjustment, significant social and economic effects

Inactive Publication Date: 2016-10-12
徐漫
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The preparation process of granular decoction pieces, the extraction is not only time-consuming and energy-consuming, but also because a large amount of water is often used as a solvent, it is difficult to extract the non-polar active ingredients in the medicinal materials
In addition, since the lobelia medicinal material used for extraction is also dried and stored for a long time, the loss of active ingredients is also very large

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0012] The freshly collected lobelia medicinal materials are cleaned, washed with water to remove the sediment, and squeezed with a press to extract juice while fresh. Add 3 times the amount of tap water to the obtained dregs, stir for 20 minutes, and press with a plate-and-frame filter press to extract the juice. The remaining medicinal dregs are squeezed with a press to extract the juice. The above-mentioned 3 concoctions were combined and filtered with a 100-mesh sieve. The filtrate was concentrated under reduced pressure and the temperature was set at 65°C. When the relative density of the concentrated extract was 1.15, the extract was frozen in a -80°C refrigerator for 6 hours. Take out the east knot, freeze-dry, the pressure is 0.09Mpa, the temperature is -20 ℃, dry for 24 hours. Take out the freeze-dried product, crush it at low temperature, pass through an 80-mesh sieve, the moisture content is not higher than 12%, pack it into a bag, 1kg / bag, add the bagged antioxi...

Embodiment 2

[0014] The freshly collected lobelia medicinal materials are cleaned, washed with water to remove the sediment, and squeezed with a press to extract juice while fresh. Add 5 times the amount of tap water to the obtained dregs, stir for 30 minutes, and press with a plate-and-frame filter press to extract the juice. The remaining medicinal dregs are squeezed with a press to extract the juice. The above-mentioned 3 concoctions were combined and filtered with an 80-mesh sieve. The filtrate was concentrated under reduced pressure and the temperature was set at 70 °C. When the relative density of the concentrated extract was 1.10, the extract was frozen in a -80°C refrigerator for 8 hours. Take out the east knot, freeze-dry, the pressure is 0.08Mpa, the temperature is -40 ℃, dry for 48 hours. Take out the freeze-dried product, crush it at low temperature, pass through a 60-mesh sieve, the moisture content is not higher than 12%, bag it, 1kg / bag, add the bagged antioxidant and des...

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Abstract

The invention discloses Chinese lobelia freshly-squeezed freeze drying powder decoction tablets and a preparation process thereof. The preparation process includes: after picking Chinese lobelia, selecting, drip-washing, freshly squeezing, and filtering to obtain medicine juice; adding water into medicine residue, stirring, filtering, and squeezing; mixing the medicine juice; depressurizing for concentrating, freeze drying, collecting a freeze drying product, smashing, and vacuum packaging. Polar and nonpolar active ingredients in the Chinese lobelia powder decoction tablets prepared by the process are retained to the greatest extent. The decoction tablets are conducive to storage and transport, convenient to compound, controllable in quality and reliable in treatment effect and are of important significance in guaranteeing clinical treatment effect of traditional Chinese medicine. The preparation process has remarkable social benefit and economic benefit in popularization and implementation.

Description

technical field [0001] The invention belongs to the field of processing Chinese medicinal materials, and in particular relates to a processing technology of Chinese medicinal lobelia decoction pieces. Background technique [0002] The traditional Chinese medicine Lobelia is a plant of Campanulaceae Lobelia Lobelia chinensis Dried whole herb of Lour. This product has the effects of diuresis, swelling, heat-clearing and detoxification, etc. It can be used to treat abdominal edema, facial and foot edema, carbuncle and furuncle, snake bites, etc. [0003] Common lobelia pieces are processed in the following ways: harvest in summer, remove sediment, wash, dry in the sun, and pack for storage and transportation. Such herbal decoction pieces are bulky, have poor hygienic indicators, are prone to pollution and mildew, and are difficult to guarantee quality, which is not conducive to formula adjustment and clinical efficacy, and even brings hidden harm to patients. [0004] At pre...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/34A61K9/14
CPCA61K36/34A61K9/14A61K2236/31A61K2236/331A61K2236/51
Inventor 徐漫
Owner 徐漫
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