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Freshly-squeezed sculellaria barbata spray-drying granular medicinal slices and preparation process thereof

A technology for drying granules and a preparation process, which is applied in the field of processing technology of traditional Chinese medicine Banzhilian decoction pieces, can solve the problems of time-consuming and energy-consuming, difficult extraction of non-polar active ingredients, large loss of active ingredients, and the like, and achieves good fluidity, Conducive to storage and transportation, clinical adjustment, and stable quality of decoction pieces

Inactive Publication Date: 2016-11-16
徐漫
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The preparation process of granular decoction pieces, the extraction is not only time-consuming and energy-consuming, but also because a large amount of water is often used as a solvent, it is difficult to extract the non-polar active ingredients in the medicinal materials
In addition, since the Scutellaria barbata medicinal material used for extraction is also dried and stored for a long time, the loss of active ingredients is also great

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0011] The freshly collected Scutellaria barbata medicinal material is cleaned, washed with water to remove sediment, cut into 3cm sections, squeezed with a press to extract juice while fresh, and retaining 1% by weight of the virgin medicinal juice for another use. Add 3 times the amount of tap water to the obtained dregs, stir for 20 minutes, and press with a plate-and-frame filter press to extract the juice. The remaining medicinal dregs are squeezed with a press to extract the juice. The above-mentioned remaining first-pressed medicinal juice is combined with the subsequent two squeezed medicinal juices, and filtered with a 100-mesh sieve. The filtrate was concentrated under reduced pressure and the temperature was set at 65 °C. When the relative density of the concentrated extract is 1.05, it is spray-dried, the air inlet temperature is 140°C, and the air outlet temperature is 100°C. The spray-dried matter is collected, crushed at low temperature, and passed through an 8...

Embodiment 2

[0013] Freshly collected Scutellaria barbata medicinal material, cleanly selected, washed with water to remove sediment, cut into 6cm segments, squeezed with a press to extract juice while fresh, and reserved 5% virgin juice by weight for another use. Add 5 times the amount of tap water to the obtained dregs, stir for 30 minutes, and press with a plate-and-frame filter press to extract the juice. The remaining medicinal dregs are squeezed with a press to extract the juice. The above-mentioned remaining first-pressed medicinal juice is combined with the subsequent two squeezed medicinal juices, and filtered with a 100-mesh sieve. The filtrate was concentrated under reduced pressure and the temperature was set at 70 °C. When the relative density of the concentrated extract is 1.10, it is spray-dried, the air inlet temperature is 120°C, and the air outlet temperature is 90°C. The spray-dried matter is collected, crushed at low temperature, and passed through an 80-mesh sieve. M...

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Abstract

The invention discloses freshly pressed spray-dried granule decoction pieces of Scutellaria barbata and a preparation process thereof. In this process, after the medicinal material of Scutellaria barbata is harvested, it is cleaned, rinsed, cut into sections, squeezed while it is fresh, and the medicinal juice is filtered. The dregs are added with water, stirred, filtered and pressed. The obtained medicinal juices are combined, concentrated under reduced pressure, spray-dried, and the spray-dried product is collected, crushed and mixed with virgin medicinal juice to make granules, granulated and then vacuum-packed. The barbata granules decoction pieces prepared by this method retain the polar and non-polar active ingredients in the medicinal materials to the greatest extent. Granular decoction pieces have good fluidity, which is convenient for storage and transportation, convenient for dispensing, controllable in quality, and reliable in curative effect, which is of great significance to guarantee the clinical curative effect of traditional Chinese medicine. The popularization and implementation of this Law will have significant social and economic benefits.

Description

technical field [0001] The invention belongs to the field of processing traditional Chinese medicinal materials, and in particular relates to a processing technology for decoction pieces of the traditional Chinese medicine Scutellaria barbata. Background technique [0002] Banzhilian Scutellaria barbata D. Don's dried whole herb. This product has heat-clearing and toxic substances removing, promoting blood circulation and removing blood stasis, reducing swelling and alleviating pain, and anti-cancer merit. Clinically, it is often used to treat appendicitis, hepatitis, cervical cancer, mastitis, etc.; external application can treat boil pain, bruises, swelling pain, etc. [0003] The commonly used processing methods of Scutellaria barbata are: harvesting in summer and autumn, removing impurities, washing, drying in the sun, and then packaging for storage and transportation. Such herbal decoction pieces are bulky, have poor hygienic indicators, are prone to pollution and mi...

Claims

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Application Information

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IPC IPC(8): A61K36/539A61K9/16A61P1/00A61P1/16A61P35/00A61P15/14A61P29/00
CPCA61K36/539A61K9/1605A61K2236/31A61K2236/51
Inventor 徐漫
Owner 徐漫
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