Traditional Chinese medicine extract for treating hyperplasia of mammary glands and extracting method and application thereof

A mammary gland hyperplasia and extract technology, which is applied in the directions of drug combination, pharmaceutical formula, and medical preparations containing active ingredients, can solve the problems of high content of heavy metals and harmful elements, extraction, etc., and achieve good dispersal, pain relief and swelling Full and damage reduction effect

Inactive Publication Date: 2016-11-16
宁夏金太阳药业有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] At present, there is no product that has a significant effect on the treatment of breast hyperplasia; the existing products generally do not extract their active ingredients to a large extent, or the content of heavy metals and harmful elements is too high

Method used

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  • Traditional Chinese medicine extract for treating hyperplasia of mammary glands and extracting method and application thereof
  • Traditional Chinese medicine extract for treating hyperplasia of mammary glands and extracting method and application thereof
  • Traditional Chinese medicine extract for treating hyperplasia of mammary glands and extracting method and application thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0110] 54g turmeric, 54g Agrimony, 45g Wulingzhi, 54g alum, 54g saltpeter, 18g dry lacquer, 90g fried Fructus Aurantii Fructus with bran, 36g Nuxychia powder;

[0111] The preparation method of extract tablet of the present invention, it comprises the steps:

[0112] (1) Take Yujinjing CO 2 Extract and raffinate obtained by supercritical extraction. CO 2 The supercritical extraction conditions are: extraction pressure 35MPa, extraction temperature 30°C, CO 2 The flow rate is 13L / h, and the extraction time is 1.5h. The pressure of separation tank I is 10-11MPa, and the temperature is 48°C; the pressure of separation tank II is 7-8MPa, and the temperature is 36°C.

[0113] (2) Alcohol extraction: take the prescription amount of bran fried Citrus aurantii, Agrimony and turmeric extract, add 8 times the amount of 80% ethanol to reflux and extract twice, each time for 2 hours, the reflux solution is left to stand for more than 12 hours, absorb the above The clear liquid is fil...

Embodiment 2

[0117] 54g turmeric, 54g Agrimony, 45g Wulingzhi, 54g alum, 54g saltpeter, 18g dry lacquer, 90g fried Fructus Aurantii Fructus with bran, 36g Nuxychia powder;

[0118] The preparation method of extract tablet of the present invention, it comprises the steps:

[0119] (1) Take Yujinjing CO 2 Extract and raffinate obtained by supercritical extraction. CO 2 The supercritical extraction conditions are: extraction pressure 35MPa, extraction temperature 30°C, CO 2 The flow rate is 13L / h, and the extraction time is 1.5h. The pressure of separation tank I is 10-11MPa, and the temperature is 48°C; the pressure of separation tank II is 7-8MPa, and the temperature is 36°C.

[0120] (2) Alcohol extraction: take the prescribed amount of bran-fried Fructus Aurantii, Agrimony and turmeric extract, add 8 times the amount of 90% ethanol to reflux and extract twice, each time for 1.5 hours, and the reflux solution is left to stand for more than 12 hours, absorb the above The clear liquid i...

Embodiment 3

[0124] 54g turmeric, 54g Agrimony, 45g Wulingzhi, 54g alum, 54g saltpeter, 18g dry lacquer, 90g fried Fructus Aurantii Fructus with bran, 36g Nuxychia powder;

[0125] The preparation method of extract tablet of the present invention, it comprises the steps:

[0126] (1) Take Yujinjing CO 2 Extract and raffinate obtained by supercritical extraction. CO 2 The supercritical extraction conditions are: extraction pressure 35MPa, extraction temperature 30°C, CO 2 The flow rate is 13L / h, and the extraction time is 1.5h. The pressure of separation tank I is 10-11MPa, and the temperature is 48°C; the pressure of separation tank II is 7-8MPa, and the temperature is 36°C.

[0127] (2) Alcohol extraction: take the prescribed amount of bran fried Citrus aurantii, Agrimony and turmeric extract, add 10 times the amount of 70% ethanol to reflux and extract twice, each time for 1.5 hours, and the reflux solution is left to stand for more than 12 hours, absorb the above The clear liquid i...

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Abstract

The invention discloses a traditional Chinese medicine extract for treating hyperplasia of mammary glands and an extracting method and application thereof. The extracting method of the traditional Chinese medicine extract comprises the following steps that 1, a CO2 supercritical technology is adopted to extract volatile oil in radix curcumae preferentially, and radix curcumae decoction dregs are taken; 2, the radix curcumae decoction dregs, a hairyvein agrimonia herb and fructus aurantii (stir-baked with bran) are subjected to alcohol extraction according to the natures of their effective components to obtain an alcohol extraction extract; 3, alumen, saltpeter, trogopterus dung and dry paint are subjected to water extraction to obtain a water extract; 4, the water extract and the alcohol extraction extract are evenly mixed. Effective parts or effective components and auxiliary components are extracted out as much as possible, inactive components such as heavy metals and tissue materials are avoided, and human harm is reduced. The traditional Chinese medicine composition has the endocrine regulating effect of soothing the liver, regulating qi, reducing phlegm, resolving masses, regulating qi, dredging collaterals, regulating thoroughfare and conception vessels and the like and can treat or assist treatment of the hyperplasia of mammary glands.

Description

technical field [0001] The invention relates to the technical field of traditional Chinese medicines, in particular to a traditional Chinese medicine extract for treating mammary gland hyperplasia and its extraction method and application. Background technique [0002] The TCM pathogenesis of mammary gland hyperplasia: traditional Chinese medicine believes that mammary gland hyperplasia is related to the liver, spleen, kidney, and Chong Ren. The ancients believed that "women's diseases mostly arise from stagnation", because women are prone to emotional changes and suffer from stagnation of the liver. At the same time, Chinese medicine believes that qi and blood are closely related, qi is blood, qi moves, blood flows, qi stagnation leads to blood stasis, and blood flow is not smooth, the mammary glands will change accordingly, so it is easy to form liver depression type mammary gland hyperplasia. [0003] The important pathogenesis of mammary gland hyperplasia is stagnation ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/9066A61P15/14A61K35/24A61K33/06A61K33/00
CPCA61K36/9066A61K33/00A61K33/06A61K35/24A61K36/22A61K36/73A61K36/752A61K2236/331A61K2236/333A61K2236/37A61K2236/39A61K2236/51A61K2300/00
Inventor 张军龙濮存海贾晓波王伏军马少平
Owner 宁夏金太阳药业有限公司
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