Composite probiotic liquid for preventing diabetes and controlling body weight and preparation method thereof
A technology for compounding probiotics and weight control, which can be used in metabolic diseases, drug combinations, pharmaceutical formulations, etc., and can solve problems such as restricting the use of metformin
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Embodiment 1
[0075] A compound probiotic liquid for preventing and treating diabetes and controlling body weight, characterized in that the composition and weight ratio of the compound probiotic are: 15 parts of Clostridium butyricum seed liquid, 15 parts of defatted soybean powder, Brassica 30 parts of yeast seed liquid, 10 parts of Lactobacillus plantarum seed liquid, 8 parts of Acetobacter xylinum seed liquid, 15 parts of Bifidobacterium adolescent seed liquid, 15 parts of Bacillus licheniformis seed liquid, 40 parts of brown sugar, 15 parts of skimmed milk powder, honey 15 parts, 3 parts of sodium chloride, 15 parts of arabinose, 8 parts of xylooligosaccharides and 800 parts of purified water. The preparation process includes: (1). Add 40 parts of brown sugar and 15 parts of defatted soybean powder into 1000L fermenter A 2 parts of sodium chloride, 400 parts of purified water, mix well and then keep warm at 115°C for 30 minutes, then cool down to 30°C; then add 30 parts of Saccharomyces...
Embodiment 2
[0093] The test was conducted on 240 obese patients with type 2 diabetes mellitus, all of which met the WHO diagnostic criteria and met the following conditions: first diagnosis or no treatment for more than half a year after diagnosis and fasting blood glucose ≥ 10.9mmol / L; no serious acute or chronic complications.
[0094] treatment method:
[0095] 240 eligible patients were divided into two groups according to the degree of obesity and the severity of diabetes.
[0096] Control group: combined with metformin on the basis of diabetes health knowledge education and diet therapy, metformin 0.5g each time, twice a day.
[0097] Experimental group: On the basis of diabetes health knowledge education and diet therapy, combined application of compound probiotic liquid, three times a day, before meals, one bottle a day. There was no significant difference in gender, age, body mass index, glycosylated hemoglobin, fasting blood sugar, and approximate onset time distribution betwee...
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