Method for establishing flora transplanting flora libraries from microorganisms in autologous health statuses

A technology of microbial flora and health status, applied in the fields of precision medicine and microbiology, can solve the problem of no uniform standard for the selection and screening of flora transplantation donors, and achieve the effect of strong psychological acceptance

Pending Publication Date: 2016-12-07
BEIHANG UNIV
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Problems solved by technology

[0005] However, there is still no uniform standard for the selection and screening of donors for flora transplantation, and there are even many controversies. The influence of donor age, health evaluation, immune rejection of flora, and safety (especially long-term safety) is still unclear. Relevant controlled studies and long-term follow-up are needed to further explore

Method used

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  • Method for establishing flora transplanting flora libraries from microorganisms in autologous health statuses

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Embodiment

[0018] In this embodiment, the method for constructing a flora library for flora transplantation by using the microorganisms in a healthy state of the body is divided into the following steps.

[0019] 1. Depositor information collection and health status confirmation. After signing the "Autologous Microflora Bank Service Agreement", depositors fill in their identity information and ask about their disease history (including whether they have a history of diarrhea and chronic constipation, whether they have a history of malignant tumors, whether they have systemic autoimmune diseases, whether they have Abuse of intravenous drugs, whether there is a history of drug use, whether there is high-risk sexual behavior, whether there is a tattoo and a history of imprisonment, etc.); after that, a physical examination and psychological evaluation should be performed, and the physical examination should include at least the following: Serum test (to check whether there are known Infecti...

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Abstract

The invention discloses a method for establishing flora transplanting flora libraries from microorganisms in autologous health statues. The method includes operation steps of 1, acquiring saver information and confirming the health statues; 2, acquiring microbial floras at autologous related positions; 3, analyzing the diversity of the microbial floras; 4, storing the microbial floras; 5, separately storing probiotics in the microbial floras; 6, establishing the libraries and carrying out information management on the libraries. The method has the advantages that transplanting for disease treatment, health protection and the like can be carried out by the aid of the microorganisms stored in the autologous health statues, and the microorganisms are high in psychological receptivity and free of immunological rejection or ethical controversy as compared with microorganisms transplanted from other people; the autologous microbial flora libraries of healthy people are established by the aid of the method, and accordingly foundations can be provided for future personalized precision medical treatment, health protection and the like.

Description

technical field [0001] The present invention is a flora library constructed by the self-organized microorganisms of a person in a healthy state for flora transplantation. In the future, the flora transplantation will be used to treat diseases, health care, etc., and relates to the fields of microbiology and precision medicine. Background technique [0002] Scientific research shows that the number of microbial cells living in the human body may reach 10 14 , more than 10 times the number of human cells, and the number of genes encoded by it is more than 100 times the number of genes in the human genome. These microbiota have important physiological functions for the human body. They help us digest food, produce various vitamins, adjust our immune system, fight harmful microorganisms, protect our skin from infection, and even affect people's body shape and mood. The treatment of human diseases is of great significance. [0003] Microorganisms live in many parts of the human...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): C40B50/06C12N1/04C12Q1/68C12Q1/04G06F19/28C12R1/225C12R1/01C12R1/145
CPCC12N1/04C12Q1/6869C12Q1/689C40B50/06G16B50/00C12Q2535/122Y02A50/30
Inventor 刘红郝梓凯谢倍珍赵文颖李乐园
Owner BEIHANG UNIV
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