High-flux chip data processing and analysis process control method for circular RNA

A process control and data processing technology, applied in the fields of design medical genomics and computational biology, can solve the problems of not knowing how to analyze and inaccurate, and achieve the effect of simple implementation method, reduced scientific research cost, and wide application range.
CN106202990AInactive Publication Date: 2016-12-07SOUTHEAST UNIV
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Patent Information

Authority / Receiving Office
CN Β· China
Current Assignee / Owner
SOUTHEAST UNIV
Publication Date
2016-12-07
Estimated Expiration
Not applicable Β· inactive patent

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Abstract

The invention discloses a high-flux chip data processing and analysis process control method for circular RNA. The method comprises the steps of generating a self-defined parameter configuration file by a system first and then generating a batch processing executable file corresponding to a data process according to a self-defined parameter file after parameter setting by a user and a high-flux chip data processing process module; and executing the batch processing executable file by the system, implementing data process automation, and finally generating a result report file. Therefore, bio-information analyzers can be efficiently assisted to finish a set of standardized high-flux data analysis process, and even scientific research personnel who do not understand high-flux data analysis can be enabled to finish the high-flux data analysis. In addition, the purposes of optimizing working efficiency of the scientific research personnel and reducing scientific research cost can be achieved. Reliable and diversified circular RNA analysis methods are proposed; and the control method also can be used for high-flux data analysis processes of long-chain non-coding RNA and the like, and is universal in different fields, simple to implement and wide in application range.
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Description

technical field

[0001] The invention is designed in the fields of medical genomics and computational biology, and specifically relates to a high-throughput chip data processing and analysis process control method for circular RNA. Background technique

[0002] Circular RNA (circular RNA, circRNA) is a recently discovered special type of non-coding RNA, which exists in large quantities in the cytoplasm of eukaryotic cells, and is mainly produced by pre-mRNA through alternative splicing. With a closed circular structure, most circular RNAs are composed of exon sequences, which are conserved in different species and have expression specificity in tissues and different developmental stages. Because circular RNA is insensitive to nucleases, it is more stable than linear RNA, which makes circular RNA have obvious advantages in the development and application of new clinical diagnostic markers. However, there are many problems in using circular RNA as a marker. For example, a larg...

Claims

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