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Montmorillonite suspension

A technology of suspension and montmorillonite, which is applied in liquid transportation, emulsion transportation, active ingredients of aluminum/calcium/magnesium, etc.

Inactive Publication Date: 2017-01-04
四川健能制药有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0009] The test results show that commercially available products that use sodium benzoate as a preservative (see authorized patent CN 101112387 B for details) can only ensure that the microbial limit in the first three days of continuous opening meets the regulations

Method used

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  • Montmorillonite suspension
  • Montmorillonite suspension
  • Montmorillonite suspension

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0023] prescription

[0024]

[0025] Process steps

[0026] Take glycerin, sodium saccharin, and milk flavor, add 500ml of purified water, stir until dissolved, add montmorillonite, stir to make it fully wet, set the volume to 1000ml, process the sample with a homogenizer for 30 minutes, mix well, and divide Packed as 90ml / bottle, ready to use.

Embodiment 2

[0028] prescription

[0029]

[0030] Process steps

[0031] Take glycerin, milk essence, and glucose, add 500ml of purified water, stir until dissolved, add montmorillonite, stir to make it fully wet, set the volume to 1000ml, process the sample with a homogenizer for 30 minutes, mix well, and pack 90ml / bottle. Instantly.

Embodiment 3

[0033] prescription

[0034]

[0035] Process steps

[0036] Take glycerin, milk essence, and glucose, add 500ml of purified water, stir until dissolved, add montmorillonite, stir to make it fully wet, set the volume to 1000ml, process the sample with a homogenizer for 30 minutes, mix well, and pack 90ml / bottle. Instantly.

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Abstract

The invention discloses a montmorillonite suspension. Each 1000ml of the suspension contains the following raw materials: 100g of montmorillonite, 100-500 g of glycerinum, 0-100 g of a sweetening agent, 0.01-10 g of essence, the balance of purified water, and the total volume is 1000ml. A preparation process comprises the following steps: taking glycerinum, the sweetening agent and the essence, adding with 40-50 % of the purified water, carrying out stirring till the glycerinum, the sweetening agent and the essence are dissolved, adding with montmorillonite, carrying out stirring till the montmorillonite is completely wet, making the constant volume, namely, the total volume, carrying out circular treatment on the sample for 15-60 min by adopting a colloid mill, a homogenizer or an emulsifying machine, and carrying out uniform mixing. The suspension is simple in preparation process, and in the storage process of the finished product after package opening, the microbial limit can meet the specification for a long period.

Description

technical field [0001] The invention relates to the technical field of pharmaceutical preparations, in particular to a montmorillonite suspension and a preparation method thereof. Background technique [0002] Diarrhea is a common symptom, commonly known as "diarrhea", which refers to the frequency of defecation significantly exceeding the usual habit, thin fecal matter, increased water content, daily defecation volume exceeding 200g, or containing undigested food or pus, blood, and mucus. Diarrhea is often accompanied by symptoms such as urgency to defecate, anal discomfort, and incontinence. Diarrhea is divided into acute and chronic categories. The onset of acute diarrhea is sharp, and the course of the disease is within 2 to 3 weeks. Chronic diarrhea refers to recurrent diarrhea with a course of more than two months or an intermittent period within 2 to 4 weeks. Diarrhea can also be divided into infectious diarrhea (such as rotavirus, bacteria, etc.) and non-infectiou...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K33/06A61K9/10A61P1/10
Inventor 王国华罗成文
Owner 四川健能制药有限公司