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Traditional Chinese medicine composition for treating rhinitis and preparation method thereof

The technology of a composition and traditional Chinese medicine is applied in the directions of drug combination, pharmaceutical formulation, drug delivery, etc., and can solve the problems of easy flow of liquid nasal drops, difficult to adhere to nasal mucosa, vasomotor rhinitis, etc., to reduce the probability of recurrence, Avoid toxic side effects and consolidate curative effects

Inactive Publication Date: 2017-01-18
青岛友诚高新技术有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] At present, there are western medicine and traditional Chinese medicine for the clinical treatment of rhinitis. Most of the western medicines are oral medicine or aqueous nasal drops. The aqueous nasal drops are easy to flow, not easy to attach to the nasal mucosa, and have a short action time. Long-term use can easily lead to vasomotor rhinitis; Chinese and Western medicines are often added with hormones, although the curative effect is fast, but it is easy to repeat, long-term use is easy to produce drug resistance, and has great side effects on the human body

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0033] (1) a kind of Chinese medicine for the treatment of rhinitis, is formed by the proportioning of following crude drugs by weight:

[0034] 30 parts of big black claw golden dragon, 25 parts of calla lily, 20 parts of chrysanthemum brain, 15 parts of loofah brain, 15 parts of flat cattail fan, 10 parts of asarum, 10 parts of cassia seed, 10 parts of typhoid grass, 10 parts of mountain magnolia flower, 5 parts of honeycomb 5 parts, 5 parts of Astragalus.

[0035] (2) Preparation method:

[0036] In the first step, calla lily and chrysanthemum brain are mixed in proportion, extracted twice with n-propanol having an alcohol concentration of 70% equivalent to twice the mass of the mixture, and the filtrates are combined, concentrated under reduced pressure, dried and pulverized into powder, and then used Purify 1-2 times with ethanol, combine the extracts, recover ethanol under reduced pressure and concentrate to a paste with a relative density of 1.21-1.24 at 60°C, dry and ...

Embodiment 2

[0041] (1) A kind of Chinese medicine for the treatment of rhinitis is formed by the proportioning of following crude drugs by weight: same as embodiment 1.

[0042] (2) Preparation method:

[0043] In the first step, calla lily and chrysanthemum brain are mixed in proportion, extracted twice with n-propanol having an alcohol concentration of 70% equivalent to twice the mass of the mixture, and the filtrates are combined, concentrated under reduced pressure, dried and pulverized into powder, and then used Purify once with ethanol, combine the extracts, recover ethanol under reduced pressure and concentrate to a paste with a relative density of 1.21-1.24 at 60°C, dry and pulverize into powder;

[0044] In the second step, the loofah brain, flat cattail fan, asarum, and cassia seeds are extracted twice with n-propanol with an alcohol concentration of 80%, the extracts are combined, concentrated under reduced pressure, dried, and pulverized into powder, and the pulverized powder is...

Embodiment 3

[0048] 1. Long-term toxicity test process:

[0049] Apply Wistar rats (Beijing Weitong Lihua Experimental Animal Technology Co., Ltd. provides) experimental medicine is set to high, medium and low three dosages, be respectively the capsule 8g / kg, 4g / kg, 2g of embodiment 1 formula / kg. Calculated according to the human dose of 0.1g / kg / day tablet, it is 80 times, 40 times and 20 times of the effective dose for human respectively; another control group is set up, which is given continuously for 90 days and 180 days by intragastric administration and part of the animals are withdrawn for 10 days. Days later, the effects on various physiological and biochemical indicators of rats were observed. The experimental results show that: continuous oral administration of different doses to rats for 180 days has no effect on the food intake and weight growth of the rats. No significant toxic effects were found on liver and kidney function. There was no obvious effect on blood routine, bl...

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PUM

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Abstract

The invention discloses a traditional Chinese medicine composition for treating rhinitis. The traditional Chinese medicine composition comprises tetrastigma lenticellatum, alocasia macrorrhiza, chrysanthemum nankingense, loofah, iris dichotoma, asarum herb, cassia seed, gray vernonia, magnolia delavayi flower, beehive and radix astragali. According to the traditional Chinese medicine composition, the raw materials are selected, the compatibility is reasonable, effects are complementary, and a good synergistic effect can be achieved. The traditional Chinese medicine composition can treat both symptoms and root causes of various acute and chronic rhinitis, the rhinitis does not occur again after being cured, a curative effect is consolidated, and the total effective rate can reach 96% or above. The traditional Chinese medicine composition is safe and becomes effective quickly, a patient's pain is small, no medicine resistance is generated, the traditional Chinese medicine composition is small in toxic and side effects and low in treatment cost and is easily accepted by patients, and the shortcoming that toxic and side effects are generated due to a large dose of western medicines is overcome. The reappearing probability of the rhinitis is reduced.

Description

technical field [0001] The invention relates to a medical preparation, in particular to a traditional Chinese medicine composition for treating rhinitis and a preparation method thereof. Background technique [0002] Rhinitis is divided into acute rhinitis and chronic rhinitis, and chronic rhinitis includes chronic simple rhinitis and chronic hypertrophic rhinitis. Chronic simple rhinitis manifests as congestion and swelling of the nasal mucosa, which is red or dark red, with intermittent and alternating nasal congestion and a large amount of nasal mucus as the main symptoms; chronic hypertrophic rhinitis has severe nasal congestion, mostly persistent, and obstructive nasal sounds , hyposmia, nasal mucus or sticky purulent, difficult to blow out, often accompanied by headache, dizziness, insomnia and listlessness and other symptoms. The above two kinds of chronic rhinitis generally have a long course of disease, and the symptoms will aggravate after fatigue and cold, and it...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/888A61K9/48A61K9/08A61P11/02A61K35/64
CPCA61K36/888A61K47/02A61K9/0019A61K9/08A61K9/1652A61K35/63A61K36/268A61K36/28A61K36/287A61K36/42A61K36/481A61K36/482A61K36/575A61K36/87A61K36/88A61K2236/333A61K2236/331A61K2236/55A61K2236/39A61K2300/00Y02A50/30
Inventor 不公告发明人
Owner 青岛友诚高新技术有限公司
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