Cell culture box

Abstract

The invention provides a cell culture box and relates to the technical field of biology experiment apparatus equipment and solves the problem of long-time placing of a culture body leaving the culture environment. The inside of an upper box body is a cell culture bin 9, and an excitation vibration device 6 provided with an elastic support base 5 is arranged inside a lower box 4; a through hole is formed in the middle of a bottom plate 7 of the upper box body, a vertical rod is arranged at the lower part of a vibration table board 8 which is located at the bottom of the cell culture bin 9, and the vertical rod penetrates through the through hole of the base plate 7 and is fixed with the excitation vibration device 6 in the lower box body; the output end of an excitation vibration power amplifier 1 is connected with the excitation vibration device 6, the vibration signal of the excitation vibration device 6 is connected with a vibration signal measuring apparatus 3 by a vibration sensor, and the output end of the vibration signal regulator 2 is in line connection with the excitation vibration power amplifier 1. The vibration table board 8 is made of an aluminum alloy plate, and equidistance screw holes in even number are formed in the vibration table board 8. The cell culture box is mainly used for providing micro-vibration stress simulation for cell culture under experiment environment.

Description

technical field [0001] The invention relates to the technical field of biological experiment equipment. Background technique [0002] Mechanical stress in vivo is a key inducer that plays a crucial role in bone growth and repair. Studies have shown that, as a stress stimulus, vibration has a good effect on promoting bone formation and bone reconstruction. Vibration stress is beneficial to bone maturation and remodeling, and vibration intensity, vibration frequency, and vibration amplitude affect the osteogenesis effect of vibration. In general, the mechanical environment with amplitude ≤ 50 μm, intensity < 1×g, and frequency range of 1-100HZ is considered to be a suitable vibration stress stimulation environment. The low amplitude, low intensity , Low-frequency vibration is also called micro-vibration. So far, the specific biological mechanism of micro-vibration is not very clear. The cellular level experiment of the micro-vibration biological effect is an important a...

AI Technical Summary

Problems solved by technology

[0004] The purpose of the present invention is to provide a cell culture box, which can effectively solve the problem of placing the culture body for a long time under the condition of leaving the culture environment

At the same time, it can effectively solve the problem that the internal structure of the incubator is unstable, which leads to the resonance of the built-in vibration device, and the problem that the error of the measured value of the generated vibration signal is higher than the allowable error of the experiment.

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