<89>SrCl2 solution production device

A technology for a production device and a dissolving device is applied in the field of radioisotope preparation to achieve the effects of reducing radiation dose, improving production efficiency and reducing radiation hazards

Active Publication Date: 2017-02-15
NUCLEAR POWER INSTITUTE OF CHINA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] The present invention solves the strontium carbonate obtained from irradiation [ 89 Sr] powder is obtained from the target tube, dissolved, filtered, and subpackaged to obtain the specific process of strontium chloride [strontium-89] solution, providing a method for realizing efficient and convenient mass production of strontium chloride [strontium-89] solution 89 SrCl 2 Solution production device

Method used

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  • &lt;89&gt;SrCl2 solution production device
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  • &lt;89&gt;SrCl2 solution production device

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0036] A sort of 89 SrCl 2 Solution production devices, such as figure 1 and figure 2 As shown, it includes a target tube crushing and dissolving device 2 , a filter device 3 , an air extraction joint 4 , a filling bottle 5 , a delivery pipeline 6 , a packing device 7 and a water pump 10 .

[0037] Wherein, the target tube crushing and dissolving device 2 includes a base 13, a crushing groove 14 arranged on the base 13, and a breaking hammer 15 placed in the crushing groove 14, such as Figure 4 shown. One end of the delivery pipe 6 communicates with the liquid inlet of the filter device 3 , and the other end extends to the inner bottom of the tank 14 .

[0038] The filter device 3 is preferably composed of a sand core filter column and a 0.1 μm-10 μm microporous filter membrane arranged in the sand core filter column. The sub-bottling 5 can be a two-necked bottle or a three-necked bottle, preferably a two-necked bottle in the present embodiment. A solution outlet and a so...

Embodiment 2

[0044] The difference between this embodiment and Embodiment 1 is that this embodiment adds a target tube cleaning device 1 for target cleaning, such as image 3 As shown, the specific settings are as follows:

[0045] The target tube cleaning device 1 includes a washing tank 11 and a drain pipe 12, the bottom of the washing tank 11 is provided with a collecting tank for collecting the liquid after washing, and an inclined guide surface for the liquid to flow to the collecting tank after washing, and the draining The lower end of the pipe 12 extends into the collection tank. The upper end of the drain pipe 12 is connected with a waste liquid collecting device 8 .

[0046] Before the target is transferred to the target tube crushing and dissolving device 2, the target is first transferred to the target tube cleaning device 1, cleaned with nitric acid, deionized water, etc., and then the washing waste liquid is discharged into the waste liquid collection device 8. .

[0047] ...

Embodiment 3

[0049] The difference between this embodiment and Embodiment 1 or 2 is that this embodiment further optimizes the structure of the target tube crushing and dissolving device 2, such as Figure 4 As shown, the specific settings are as follows:

[0050] A funnel 16 is also arranged on the top of the crushing tank 14, and a baffle 17 is arranged in the funnel 16 to prevent debris and samples from splashing out during crushing. The target tube crushing and dissolving device 2 is also connected with a peristaltic pump 9 for inputting the solution for dissolving the powder in the target. Through the arrangement of the peristaltic pump 9, not only can effectively realize the continuous production of products, but also can effectively add cleaning solution to realize cleaning of the whole device of the present invention, and the operation is more convenient.

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PUM

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Abstract

The invention provides a <89>SrCl2 solution production device, and solves the problem that strontium carbonate powders obtained after irradiation are obtained, dissolved, filtered and separated in a target tube, and thus the specific process of the obtained strontium chloride solution cannot realize efficient and simple batch production. The production device comprises a target tube breaking and dissolving device (2) for target breaking and in-target powder dissolving, a filter device (3) for filtering dissolved liquid, a separation bottle (5) connected with the filter device (3), an air extraction connector (4) connected with the filter device (3) and the separation bottle (5), and a water pump (10) communicated with the air extraction connector (4). A liquid inlet of the filter device (3) is communicated to the bottom end of the target tube breaking and dissolving device (2) through a transmission pipeline (6). The <89>SrCl2 solution production device has the advantages of being fast to operate, simple and efficient; the production device is convenient to clean after production; liquid waste can be discharged immediately, thereby reducing the risk of radiation pollution; and the device is compact in structure, is simple and efficient, and is suitable for continuous production.

Description

technical field [0001] The invention belongs to the technical field of radioisotope preparation and relates to a 89 SrCl 2 Solution production device. Background technique [0002] 89 Sr is a β-radioactive nuclide, its physical half-life is 50.53d, and it mainly emits β-rays when it decays. - The maximum energy of the ray is 0.586 MeV (9.6×10 -3 %) and 1.495 MeV (99.99%), the average energy is 0.56 MeV, and the gamma ray energy is 0.909 MeV (9.6×10 -3 %), is an ideal therapeutic nuclide. strontium chloride [ 89 Sr] is mainly used for the relief of bone pain caused by bone metastasis of advanced malignant tumors such as prostate cancer and breast cancer. radiopharmaceuticals. At present, it has become a routine treatment item in many hospitals and has a good market prospect. [0003] Currently, 89 Sr has target neutron irradiation production and uranium fission product extraction and other preparation methods. Among them, there are two ways for target neutron irradi...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): G21G1/02
CPCG21G1/02
Inventor 罗宁姚维华曾俊杰陈云明张劲松李蓓孙志中胡银冯伟伟李兵江常玉
Owner NUCLEAR POWER INSTITUTE OF CHINA
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