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A kind of human-like collagen anorectal mucosa repair gel

A human-like collagen, anorectal technology, applied in bandages, medical science, etc., can solve the problems of transdermal absorption speed of collagen that have not been paid attention to, and achieve the effect of accelerating transdermal absorption speed, promoting repair, and good nourishment

Active Publication Date: 2021-09-17
SHAANXI GIANT BIOTECHNOLOGY CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

But unfortunately, relevant researches pay more attention to the transdermal absorption rate of collagen, but not the transdermal absorption rate of collagen

Method used

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  • A kind of human-like collagen anorectal mucosa repair gel
  • A kind of human-like collagen anorectal mucosa repair gel
  • A kind of human-like collagen anorectal mucosa repair gel

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preparation example Construction

[0033] There is no special limitation on the preparation method of the human-like collagen gel of the present invention, and its preparation method may include:

[0034] Step A: preparing phase A, the phase A is composed of 0.75-0.85% by weight of carbomer, 5-10% by weight of glycerin, 0.001-0.01% by weight of sodium hyaluronate and the rest of water;

[0035] Step B: preparing phase B, which is an aqueous sodium hydroxide solution composed of 0.12 to 0.2% by weight of sodium hydroxide and 1 to 3% by weight of water;

[0036] Step C: preparing phase C, which is a mixture of 0.1-0.5% by weight of ethylparaben and 20-10% by weight of glycerol;

[0037] Step D: preparing phase D, the phase D is 0.2-1% by weight of chitosan;

[0038] Step E: preparing phase E, the phase E is human-like collagen solution, which contains human-like collagen such that the content of human-like collagen in the human-like collagen anorectal mucosa repair gel is 0.1-1% by weight protein, the medium is...

Embodiment 1

[0051] Embodiment 1. Preparation of human-like collagen anorectal mucosa repair gel of the present invention

[0052] Ingredients: Carbomer 0.8%, Glycerin 22%, Sodium Hyaluronate 0.005%, Sodium Hydroxide 0.15%, Ethylparaben 0.2%, Chitosan 0.5%, Human Collagen 0.5%, The balance is water.

[0053] Process operation:

[0054] ① Add carbomer, sodium hyaluronate, and glycerin (8% by weight) to water first, then slowly add chitosan and stir continuously until they are completely dispersed.

[0055] ② Add sodium hydroxide aqueous solution to the above solution, stir evenly, slowly add the mixture of ethylparaben and glycerin, and human-like collagen solution, stir well, keep warm at 82°C for 90 minutes, after the warming is over, Stir well and cool to room temperature.

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Abstract

The invention relates to a human-like collagen anorectal mucosa repair gel. The human-like collagen anorectal mucosa repair gel of the present invention comprises 0.1-1% by weight of human-like collagen, 0.75-0.85% by weight of carbomer, 20-25% by weight of glycerin, 0.001-0.01% by weight of sodium hyaluronate, hydrogen 0.12-0.2% by weight of sodium oxide, 0.1-0.5% by weight of ethylparaben, 0.2-1% by weight of chitosan, and the rest of water. When the human-like collagen gel of the present invention is applied to the anorectal epidermis with damaged mucosa, the transdermal absorption speed of the human-like collagen can be more significantly accelerated. Therefore, the human-like collagen gel of the present invention can provide better nourishment, stimulate the regeneration of mucosal cells, and promote the repair of damaged anorectal mucosa.

Description

technical field [0001] The invention relates to a human-like collagen dressing, in particular to a gel containing human-like collagen which is particularly suitable for repairing anorectal mucosa, and belongs to the field of health care / medical equipment. Background technique [0002] Human-like collagen was invented by Professor Fan Daidi of Northwest University in China (see Chinese Patent Application Publication CN1371919A), so it is also called Fan's Human-like Collagen or Fan's Human-like Collagen (FHLC). Human-like collagen is a highly biocompatible recombinant collagen that is currently widely used in medical or cosmetic fields. [0003] On the other hand, when collagen dressings are used to moisten and protect the mucous membranes of the nasal cavity, anorectum, and gynecology, the use of collagen dressings often needs to be done indoors (such as the otolaryngology, anorectal, and gynecology departments of hospitals, etc.) , as a product user hopes to be able to com...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61L26/00
CPCA61L26/0014A61L26/0023A61L26/0033A61L26/008C08L89/00C08L5/08C08L33/02
Inventor 范代娣马晓轩严建亚王淑英常海燕王小军杨婵媛
Owner SHAANXI GIANT BIOTECHNOLOGY CO LTD
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