A kind of Chinese herbal antihypertensive tea and preparation method thereof
A technology for antihypertensive tea and licorice, which is applied in pharmaceutical formulations, drug combinations, tea substitutes and other directions, can solve problems such as inability to exert efficacy and insufficient pretreatment of Chinese herbal medicine raw materials, and achieve scientific and reasonable preparation methods, simple and easy-to-find prescriptions, exact effect
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experiment example 1
[0042] In parts by weight, there are 9 parts of ghost needle grass, 1 part of astragalus, 1 part of licorice, 3 parts of Prunella vulgaris, and 3 parts of gongying, and a total of 100 g of raw materials are weighed. Wash the raw materials with enough deuterium-depleted water, and after drying, add 1L deuterium-depleted water and cellulase to treat the raw materials. In the present invention, the concentration of cellulase, reaction temperature, and reaction time are screened.
[0043] Since cellulase can digest cellulose in raw materials to obtain glucose, in this experiment, the concentration of glucose in the solution was used as an indicator of the degree of enzymatic hydrolysis. At the same time, the content of flavonoids and polysaccharides in the solution should be detected to avoid the loss of active ingredients caused by excessive digestion of cellulose.
[0044] Detection method of flavonoids: Accurately weigh 9.5 mg of anhydrous rutin, dilute it in a 50 mL volumetric ...
experiment example 2
[0053] In parts by weight, there are 9 parts of ghost needle grass, 1 part of astragalus, 1 part of licorice, 3 parts of Prunella vulgaris, and 3 parts of gongying, and a total of 100 g of raw materials are weighed. Wash the respective raw materials with sufficient deuterium-depleted water, and after drying, add an appropriate amount of NaCl solution to treat the raw materials. In the present invention, the concentration of NaCl and the salt immersion time are screened.
[0054] Since the salt leaching of raw materials is to reduce the water content in the raw materials and soften the raw materials through a hyperosmotic environment, the effect can only be judged by the extraction rate of flavonoids and polysaccharides after salt leaching.
[0055] Filter the salted raw material, dissolve it in 1000ml 40% ethanol solution, and detect the flavonoid and polysaccharide content according to the method of Example 1 after 15 minutes. As shown in Table 3, when the NaCl concentration...
experiment example 3
[0059] In parts by weight, there are 9 parts of ghost needle grass, 1 part of astragalus, 1 part of licorice, 3 parts of Prunella vulgaris, and 3 parts of gongying, and a total of 100 g of raw materials are weighed. Wash the raw materials with enough deuterium-depleted water, after drying, add 1L deuterium-depleted water, add 0.5% cellulase, enzymatically hydrolyze for 1h, filter, dissolve the residue in 1L of 40% ethanol, and extract by ultrasonic. Adjust the ultrasonic power and ultrasonic time, and detect the content of total polysaccharides and flavonoids in the solution according to the method of Experimental Example 1.
[0060] The applicant unexpectedly found that when the ultrasonic time was 15 minutes and the ultrasonic power was 280w, the total flavonoid content in the solution was the highest, and the longer the ultrasonic time and the higher the ultrasonic power, the flavonoid content in the solution could not be significantly increased. The applicant speculates th...
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