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Haemostatic wound dressing and preparation process thereof

A hemostatic dressing and a preparation technology, which is applied in the field of hemostatic dressing, can solve the problems of increased platelet aggregation and coagulation factor concentration time, unsatisfactory hemostatic effect, and large particle size, so as to shorten the generation time, quickly and reliably stop bleeding, and repair blood vessels and organizational effects

Inactive Publication Date: 2017-05-24
陈静
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Ordinary powder medicines have large particle size, large number of atoms in the particles, and few atoms distributed on the surface. When the ordinary powder medicine dressing is directly applied to the wound, it will not selectively absorb water molecules in the blood, and will Absorb other components in the blood, which will greatly increase the concentration time of platelet aggregation and coagulation factors, and its hemostatic effect is not very ideal

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0021] A hemostatic dressing comprising cuttlefish made into a nanoscale powder.

[0022] The preparation technology of above-mentioned hemostatic dressing, comprises the following steps:

[0023] Step 1: Wash the sea octopus first, and use tap water to remove impurities and soil on the sea octopus;

[0024] Step 2, finely washing the sea octopus, soaking and cleaning the sea octopus with deionized water;

[0025] Step 3, drying the washed sea octopus with hot air at 80°C-100°C;

[0026] Step 4, pulverizing the dried sea octopus by mechanical ball milling or jet milling until the diameter of the sea octopus powder is 30 microns to 50 microns;

[0027] Step 5, pack the sea octopus powder with a plastic film or aluminum foil that can pass through ethylene oxide, pack it according to 50g / bag or 100g / bag, put it into a medium-sized epoxy sterilizer for sterilization, or use Cobalt 60 is irradiated for sterilization, wherein the concentration of ethylene oxide is 800MG-1000MG / L,...

Embodiment 2

[0030] A hemostatic dressing, which comprises sea octopus made into nano-scale powder and bletilla striata made into nano-scale powder, wherein the weight component ratio of sea octopus to bletilla striata is: 1-10 parts of sea octopus, 1-10 parts of bletilla striata 10 servings. The optimum weight-component ratio of sea octopus and bletilla striata is: 1 part of sea octopus and 1 part of bletilla striata.

[0031] The preparation technology of above-mentioned hemostatic dressing, comprises the following steps:

[0032] Step 1, washing the sea octopus and bletilla striata for the first time, and using tap water to remove impurities and soil on the sea octopus and bletilla striata;

[0033] Step 2, finely washing sea octopus and bletilla striata, soaking sea octopus and bletilla striata with deionized water;

[0034] Step 3, drying the washed sea octopus and bletilla striata with hot air at 80°C-100°C;

[0035] Step 4, using mechanical ball milling or jet milling to pulveriz...

Embodiment 3

[0040] A hemostatic dressing, which comprises sea octopus made into nano-scale powder and cattail yellow made into nano-scale powder, wherein, the weight component ratio of sea octopus to cattail is: 1-10 parts of sea clam, 10 parts of cattail Yellow 1-10 parts. The optimum weight component ratio of sea octopus and cattail is: 1 part of sea cucumber and 1 part of cattail.

[0041] The preparation technology of above-mentioned hemostatic dressing, comprises the following steps:

[0042] Step 1, washing the sea octopus and cattail first, and using tap water to remove impurities and soil on the sea octopus and cattail;

[0043] Step 2, washing the squid octopus and Puhuang finely, soaking the squid octopus and Puhuang with deionized water;

[0044] Step 3, drying the washed sea octopus and cattail with hot air at 80°C-100°C;

[0045] Step 4, using mechanical ball milling method or jet milling method to pulverize the dried sea octopus and cattail respectively, until the diamete...

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Abstract

The invention discloses a haemostatic wound dressing. The haemostatic wound dressing is prepared from cuttlebone made into nano-grade powder. The haemostatic wound dressing can also be prepared from rhizoma bletillae or pollen typhae or radix notoginseng which is made into nano-grade powder. The invention further discloses a preparation process for the haemostatic wound dressing. The preparation process comprises the following steps: washing the cuttlebone with water and drying; smashing the dried cuttlebone into the nano-grade powder; sterilizing the cuttlebone made into the nano-grade powder. The haemostatic wound dressing has the effects of shortening the generation time of thrombin, inhibiting the activity of fibrinolysin, contracting blood vessels and the like, and has the characteristics of rapid and reliable hemostasis and prevention of blood stasis in hemostasis; the conventional Chinese medicinal herbs are processed and modified into the nano-grade powder to obtain a novel functional hemostasis material for repairing blood vessels and tissues at bleeding positions.

Description

technical field [0001] The invention relates to a technique in the field of hemostatic dressing, in particular to a hemostatic dressing and a preparation process thereof. Background technique [0002] In the existing hemostatic dressings, the medicine is generally directly ground into a common powder, and then the medicine powder is sprinkled on the bleeding wound, and then the wound is bandaged. Ordinary powdered medicines have large particle size, large number of atoms in the particles, and few atoms distributed on the surface. When the ordinary powdered drug dressing is directly applied to the wound, it will not selectively absorb water molecules in the blood, and will Absorbing other components in the blood will greatly increase the concentration time of platelet aggregation and coagulation factors, and its hemostatic effect is not very ideal. Contents of the invention [0003] Based on this, it is necessary to propose a hemostatic dressing capable of rapid hemostasis...

Claims

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Application Information

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IPC IPC(8): A61L24/00
CPCA61L24/0005A61L24/001A61L24/0015A61L2300/30A61L2300/418A61L2400/04A61L2400/12
Inventor 陈静
Owner 陈静
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