Feed additive capable of preventing rex rabbit clostridium welchii disease and preparation method of feed additive

Abstract

The invention discloses a feed additive capable of preventing a rex rabbit clostridium welchii disease and a preparation method of the feed additive. The feed additive is prepared from rhizoma coptidis, cortex phellodendri, rheum officinale, oxalis corymbosa herb, crickweed herb, white clovers herb, herba artemisiae annuae, goral horns, concha margaritifera usta, olive oil, diatomite, sodium bicarbonate, dry yeasts, comprehensive vitamins and nicotinic acid by carrying out technologies including crushing, extraction with ethanol and microwave radiation. The feed additive can lower the stress response of a rex rabbit and enhance the immunocompetence of the rex rabbit; can effectively inhibit aflatoxin caused by feed mildewing, prolong the conservation time of a feed and improve the quality of the feed so as to prevent the rex rabbit incidence caused by feed mildewing; is rich in plant crude fibers, has the efficiency of regulating an endocrine system, improves the gastrointestinal micro-ecological environment of the rex rabbit and ensures the quality of hairs of the rex rabbit; and can strengthen the effect of preventing the rex rabbit clostridium welchii disease, lower the incidence and the mortality of the rex rabbit clostridium welchii disease, and thus reaching the purposes of lowering the culturing cost and risk and increasing the culturing economic benefit.

Description

technical field [0001] The invention relates to the technical field of rex rabbit breeding, in particular to a feed additive capable of preventing clostridium welchii disease of rex rabbits and a preparation method thereof. Background technique [0002] Rex rabbit, whose scientific name is Lex rabbit, was originally produced and is a typical fur rabbit. Because its fur resembles that of the fur beast otter, it is named Rex rabbit; The resistance to the disease is very weak, and when it is severe, the mortality rate of rex rabbits over 3 months old can reach 100%. Due to the limitation of breeding costs and breeding sites, in the current breeding process of rex rabbits, there are basically low levels of feeding management and high stocking density; The air in the house is dirty and the ventilation is insufficient; summer is cold and humid, bacterial diseases increase, and various stress factors lead to the problem of increased infectivity; for many years, respiratory infectio...

AI Technical Summary

Problems solved by technology

[0002] Rex rabbit, whose scientific name is Lex rabbit, was originally produced and is a typical fur rabbit. Because its fur resembles that of the fur beast otter, it is named Rex rabbit; The resistance to the disease is very weak, and when it is severe, the mortality rate of rex rabbits over 3 months old can reach 100%. Due to the limitation of breeding costs and breeding sites, in the current breeding process of rex rabbits, there are basically low levels of feeding management and high stocking density; The air in the house is dirty and the ventilation is insufficient; summer is cold and humid, bacterial diseases increase, and various stress factors lead to the problem of increased infectivity; for many years, respiratory infectious diseases have been common in rex rabbit farms. Environmental factors such as high stocking density and poor management are the direct causes of the occurrence and prevalence of rex rabbit disease, while poor sanitation in the rabbit house will cause cross-contamination of feed, accelerate feed mildew, and further cause digestive tract diseases, secondary infection, mixed Increased number of infection cases, short course of disease, atypical symptoms, complex lesions and other factors are the main factors leading to the high mortality rate in the breeding process of rex rabbits

[0003] Clostridium welchii, also known as Clostridium perfringens, can form capsules in animals and has strong resistance. It can be killed by soaking in 10% formalin solution for 10 minutes; It is a kind of infectious disease of rex rabbits caused by Clostridium welchii, mainly caused by type A and type E bacteria and the alpha toxin produced; pathogenic bacteria invade the body from the digestive tract or wounds, reproduce in large numbers on the small intestine and cecum chorion and Produce strong α-toxin, change the permeability of capillaries, make the toxin enter the blood in large quantities, and cause systemic toxemia; because of its rapid onset, strong infectivity, and difficult identification of diseases, sick rex rabbits often have diarrhea on the day Or die within two to three days. Therefore, even if antibiotic treatment is carried out in time, good results cannot be achieved. The death of rex rabbits caused by Clostridioides welchii disease has seriously restricted the economic benefits of current rex rabbit breeding

[0004] In the prior art, the prevention of Clostridium welchii disease in rex rabbits is still in the passive stage. We can only do a good job in the feeding management and veterinary epidemic prevention and sanitation work in the rabbit farm at ordinary times, so as to reduce the factors that cause stress. For rabbit farms with medical history, it is generally Adopt type A clostridium welchii formaldehyde inactivated vaccine or concentrated formaldehyde inactivated vaccine immunization; yet still can't avoid the outbreak of rex rabbit clostridium welchii disease; and after the onset, it is necessary to do isolation treatment and disinfection work quickly, prior art The commonly used Western medicine therapy is: at the beginning of the disease, flatulence and laxative appetizing needle can be used for treatment, subcutaneous and intramuscular injection; oral administration of olaquindox; intramuscular injection of aureomycin or erythromycin; intramuscular injection of kanamycin; and intravenous or Intraperitoneal injection of glucose saline for body fluid supplementation; even if the diarrhea is treated, there are still death cases; and the rex rabbit population in the rabbit house generally has low immunity and high morbidity; The prevention of clostridial disease, reducing the stress response of rex rabbits and improving the immunity of rex rabbits are problems that need to be solved urgently in the breeding technology of rex rabbits