Method and system for positioning cerebral-cortex hand functional region by applying electrocorticogram signals

An EEG signal and cerebral cortex technology, which is applied in the field of biomedical engineering, can solve the problems of epileptic seizures, low time resolution, and high inspection costs in patients, and achieve the effects of short data acquisition time, simple method operation, and avoidance of signal loss.

Active Publication Date: 2017-05-31
ZHEJIANG UNIV
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  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

[0007] There are certain defects in this method: (1) the inspection time is long, and both the patient and the doctor are prone to fatigue and irritability; (2) the stimulation intensity is not easy to control, and it is easy to cause diffusion in the brain to affect the activation of other regions, resulting in false positives. Positive reaction and poor repeatability; (3) For cortical stimulation before epileptogenic focus resection, it may induce seizures in patients
[0010] This method has certain defects: first, the equipment is expensive and the inspection cost is high; second, the time resolution is relatively low, and continuous brain activation information cannot be recorded

Method used

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  • Method and system for positioning cerebral-cortex hand functional region by applying electrocorticogram signals
  • Method and system for positioning cerebral-cortex hand functional region by applying electrocorticogram signals
  • Method and system for positioning cerebral-cortex hand functional region by applying electrocorticogram signals

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Embodiment 1

[0047] see figure 1 In this embodiment, a system for locating hand functional areas of the cerebral cortex is provided. It mainly includes a prompt display 1, an ECoG electrode 2, a splitter 3, a signal acquisition subsystem 4, a data glove 5, and an analysis and control subsystem 6 (computer 6). The analysis and control subsystem 6 provides visual movement instructions to the subject by prompting the display 1. When the subject performs a specific hand movement according to the instruction, the analysis and control subsystem 6 passes the EEG signal acquisition subsystem 4 and the branch line The cortical EEG signal of the subject is collected from the ECoG electrode 2 of the subject on the device 3, and the analysis and control subsystem 6 synchronizes the hand movement signal through the data glove 5 at the same time; After a series of analysis and processing by the analysis and control subsystem 6, the cerebral cortex area corresponding to the hand movement is finally loca...

Embodiment 2

[0064] In this embodiment, a method for locating hand functional areas of the cerebral cortex is provided. Including the following steps, see the flow chart figure 2 shown.

[0065] Step 1: Acquire cortical EEG signals and hand movement signals respectively: when the patient performs three gesture tasks, use ECoG electrode 2 to complete the collection of cortical EEG signals, and use data glove 5 to complete the collection of hand movement signals at the same time . Among them, the gesture task process is as follows image 3 As shown: firstly, the patient is in a resting state, and performs corresponding gestures according to the random gesture instructions on the prompt display; then, the gestures are kept until the end of the prompt; after the execution of the gesture is completed, the patient returns to the resting state, waiting for the next prompt, The whole process is a trial. The course of an experimental task lasts about ten minutes. There were at least three exp...

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Abstract

The invention provides a method and system for positioning a cerebral-cortex hand functional region by applying electrocorticogram (ECoG) signals. The system comprises a prompt display, an ECoG electrode, a deconcentrator, a signal acquisition subsystem, a data glove and an analysis and control subsystem. The method includes: acquiring original electrocorticogram signals and hand motion signals prior to processing the same through the system while hand motion is executed according to prompt of the display; acquiring motion starting moment and hand motion types according to original hand motion signals; intercepting the electrocorticogram signals in corresponding time period according to the hand motion starting moment; calculating power spectrum of the electrocorticogram signals subjected to preprocessing; performing classified decoding on the hand motion by the aid of the hand motion types and the intercepted power spectrum; performing significance analysis among different channels according to classified encoding results and positioning the cerebral cortex region corresponding to the hand motion according to significance analysis results. The method and system is reasonable in design and simple in operation, extra electric stimulation on the brain is not needed, and an assistance is provided for planning of specified epileptogenic focus resection operation.

Description

technical field [0001] The invention belongs to the field of biomedical engineering, and relates to a method and a system for locating hand functional areas of the cerebral cortex by using electroencephalographic signals recorded by cortical electrocorticography (ECoG) electrodes. Background technique [0002] In the craniotomy for the treatment of traditional intractable epilepsy, accurately grasping the location of the epileptic focus on the cerebral cortex and resecting it is one of the difficulties faced by neurosurgeons. Since different regions of the cerebral cortex correspond to different functions of the human body, improper resection may It will cause permanent neurological impairment in patients, so it is very important to locate the functional areas of the brain. [0003] The motor sensory functional area of ​​the brain is the body motor center and the somatosensory center, which are located in the precentral gyrus and postcentral gyrus of the brain respectively. ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61B5/0476A61B5/11A61B5/00G06F3/01G06F17/14G06K9/62
CPCA61B5/1116A61B5/4094G06F3/014G06F17/14A61B5/7225A61B5/316A61B5/369G06F18/2411
Inventor 张韶岷王晓田郑宇新朱君明陈杭郑筱祥
Owner ZHEJIANG UNIV
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