Method and system for locating hand functional areas in cerebral cortex by using cortical EEG signals

An EEG signal and cerebral cortex technology, applied in the field of biomedical engineering, can solve the problems of patients with epileptic seizures, low time resolution, and high inspection costs, and achieve the effects of short data acquisition time, high spatial resolution, and avoiding signal loss.

Active Publication Date: 2020-02-21
ZHEJIANG UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0007] There are certain defects in this method: (1) the inspection time is long, and both the patient and the doctor are prone to fatigue and irritability; (2) the stimulation intensity is not easy to control, and it is easy to cause diffusion in the brain to affect the activation of other regions, resulting in false positives. Positive reaction and poor repeatability; (3) For cortical stimulation before epileptogenic focus resection, it may induce seizures in patients
[0010] This method has certain defects: first, the equipment is expensive and the inspection cost is high; second, the time resolution is relatively low, and continuous brain activation information cannot be recorded

Method used

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  • Method and system for locating hand functional areas in cerebral cortex by using cortical EEG signals
  • Method and system for locating hand functional areas in cerebral cortex by using cortical EEG signals
  • Method and system for locating hand functional areas in cerebral cortex by using cortical EEG signals

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Embodiment 1

[0047] see figure 1 In this embodiment, a system for locating hand functional areas of the cerebral cortex is provided. It mainly includes a prompt display 1, an ECoG electrode 2, a splitter 3, a signal acquisition subsystem 4, a data glove 5, and an analysis and control subsystem 6 (computer 6). The analysis and control subsystem 6 provides visual movement instructions to the subject by prompting the display 1. When the subject performs a specific hand movement according to the instruction, the analysis and control subsystem 6 passes the EEG signal acquisition subsystem 4 and the branch line The cortical EEG signal of the subject is collected from the ECoG electrode 2 of the subject on the device 3, and the analysis and control subsystem 6 synchronizes the hand movement signal through the data glove 5 at the same time; After a series of analysis and processing by the analysis and control subsystem 6, the cerebral cortex area corresponding to the hand movement is finally loca...

Embodiment 2

[0064] In this embodiment, a method for locating hand functional areas of the cerebral cortex is provided. Including the following steps, see the flow chart figure 2 shown.

[0065] Step 1: Acquire cortical EEG signals and hand movement signals respectively: when the patient performs three gesture tasks, use ECoG electrode 2 to complete the collection of cortical EEG signals, and use data glove 5 to complete the collection of hand movement signals at the same time . Among them, the gesture task process is as follows image 3 As shown: firstly, the patient is in a resting state, and performs corresponding gestures according to the random gesture instructions on the prompt display; then, the gestures are kept until the end of the prompt; after the execution of the gesture is completed, the patient returns to the resting state, waiting for the next prompt, The whole process is a trial. The course of an experimental task lasts about ten minutes. There were at least three exp...

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Abstract

The present invention provides a method and system for locating the hand functional area of ​​the cerebral cortex. The system includes a prompt display, ECoG electrodes, a wire splitter, a signal acquisition subsystem, a data glove, and an analysis and control subsystem. At the same time, the system collects and processes raw cortical EEG signals and hand movement signals. The system obtains the starting moment of movement and the type of hand movement according to the original hand movement signal, intercepts the cortical EEG signal in the corresponding time period according to the starting moment of hand movement, and then calculates its power spectrum after preprocessing the cortical EEG signal. Use the hand movement type and intercepted power spectrum to classify and decode the hand movement, perform significance analysis between different channels according to the classification and decoding results, and locate the cerebral cortex area corresponding to the hand movement through the significance analysis results. The invention is reasonable in design, simple in method operation, does not need to perform additional electric stimulation on the brain, and provides help for the operation planning of designated epileptic foci resection.

Description

technical field [0001] The invention belongs to the field of biomedical engineering, and relates to a method and a system for locating hand functional areas of the cerebral cortex by using electroencephalographic signals recorded by cortical electrocorticography (ECoG) electrodes. Background technique [0002] In the craniotomy for the treatment of traditional intractable epilepsy, accurately grasping the location of the epileptic focus on the cerebral cortex and resecting it is one of the difficulties faced by neurosurgeons. Since different regions of the cerebral cortex correspond to different functions of the human body, improper resection may It will cause permanent neurological impairment in patients, so it is very important to locate the functional areas of the brain. [0003] The motor sensory functional area of ​​the brain is the body motor center and the somatosensory center, which are located in the precentral gyrus and postcentral gyrus of the brain respectively. ...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61B5/0476A61B5/11A61B5/00G06F3/01G06F17/14G06K9/62
CPCA61B5/1116A61B5/4094G06F3/014G06F17/14A61B5/7225A61B5/316A61B5/369G06F18/2411
Inventor 张韶岷王晓田郑宇新朱君明陈杭郑筱祥
Owner ZHEJIANG UNIV
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