Oral care composition for treating xerostomia and application of oral care composition in toothpaste

A technology of oral care and composition, applied in the field of oral care composition and its application in toothpaste, which can solve the problems of insignificant effect, insignificant therapeutic effect, short action time, etc., and achieve stable effect

Active Publication Date: 2017-05-31
广东省九科生物科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Due to the short action time of the oral care composition in the oral cavity and the low residual amount of active substances in the oral cavity, the therapeutic effect of this method is not significant, especially for some people with hyposecretion of salivary glands, the e

Method used

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  • Oral care composition for treating xerostomia and application of oral care composition in toothpaste
  • Oral care composition for treating xerostomia and application of oral care composition in toothpaste
  • Oral care composition for treating xerostomia and application of oral care composition in toothpaste

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1-5

[0068] Application of the dry mouth treatment composition involved in the present invention in toothpaste. According to the following formula and production process, the toothpaste with the effect of treating dry mouth is prepared.

[0069] The production preparation technology of above embodiment 1-5 is as follows:

[0070]

[0071]

[0072] According to the preparation process of biological enzymes, the biological enzymes in the formula are mixed to prepare biological enzyme microspheres; the preparation method of biological enzyme microspheres:

[0073] (1) Take the water of formula quantity and heat to boiling, add starch binder under stirring condition and stir for 30min;

[0074] (2) Cool the starch binder mixture to 30°C, homogenize and add biological enzymes, homogenize for 10 minutes;

[0075] (3) Using fluidized bed equipment, set the parameter air volume to 1150m 3 / H, the inlet air temperature is 65° C., and the spray gun pressure is 0.24 MPa, the stream p...

Embodiment 6-9

[0088] The application of the dry mouth treatment composition involved in the present invention in mouthwash. According to the following formula and production process, the mouthwash solution with the effect of treating dry mouth is prepared.

[0089]

[0090] The preparation method of the oral care composition: uniformly mix the biological enzyme and the Chinese herbal medicine extract to obtain the oral care composition.

[0091] The mouthwash preparation process of above embodiment 6-9 is as follows:

[0092] (1) Dissolve poloxamer and betaine in water, stir for 15 minutes to fully dissolve, add essence, and stir for 5 minutes; add the obtained oral care composition, sorbitol, sodium saccharin, xylitol, and sodium fluoride to In the above aqueous solution, stir for 30min, and leave to stand to obtain the aqueous solution;

[0093](2) Disperse CMC and carbomer into glycerin, stir for 5 minutes, and disperse evenly;

[0094] (3) Add the glycerol mixture described in ste...

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Abstract

The invention discloses oral care composition for treating xerostomia and an application of the oral care composition in toothpaste. The oral care composition for treating xerostomia contains Chinese herbal medicine extract and bio-enzyme, wherein the Chinese herbal medicine extract is one or more of dendrobium extract, radix polygonati officinalis extract and radix ophiopogonis extract; the bio-enzyme is one or more of lysozyme, lactoperoxidase, amylase, amyloglucosidase and glucose oxidase. The oral care composition has the effect of relieving xerostomia, on one hand, the oral care composition can stimulate salivary secretion, and on the other hand, the oral care composition contains a component similar to protein or enzyme in saliva, thereby being capable of playing the role of artificial saliva, having the sterilization effect and being capable of relieving discomfort caused by xerostomia after use.

Description

technical field [0001] The invention relates to the technical field of oral care products, in particular to an oral care composition for treating dry mouth and its application in toothpaste. Background technique [0002] Saliva plays an important role in lubricating digested food, cleaning the mouth and protecting it from chemical, mechanical and infectious agents. Normal saliva contains antibodies, enzymes and buffers. It prevents the progression of caries by maintaining a normal pH of the oral environment, making it neutral, limiting the production of acids due to the degradation of sugars. Salivary enzymes act at the beginning of food digestion. Saliva is also important for taste and language. [0003] Insufficient saliva production can lead to dry mouth. Xerostomia is not uncommon clinically, especially in the elderly. Other factors such as radiation therapy, antidepressants, and the more frequent use of anticholinergics, antiallergics, antihistamines, anticonvulsan...

Claims

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Application Information

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IPC IPC(8): A61K38/47A61K9/16A61P1/02A61P31/04A61K8/9794A61K8/66A61Q11/00A61Q17/00A61K36/8984A61K36/8969A61K36/8968A61K38/44
CPCA61K8/66A61K8/97A61K9/1605A61K36/8968A61K36/8969A61K36/8984A61K38/44A61K38/443A61K38/47A61K2236/331A61K2236/333A61K2236/39A61K2236/51A61K2236/53A61Q11/00A61Q17/005A61K2300/00
Inventor 江山
Owner 广东省九科生物科技有限公司
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