A diagnostic marker for bladder cancer and its application and diagnostic kit

A technology for diagnosing marker and bladder cancer, applied in the field of biomedicine, can solve the problems of invasive cost of cystoscopy, easy missed diagnosis of bladder carcinoma in situ, misdiagnosis, low detection sensitivity, etc., and achieve good diagnostic efficiency and diagnostic results. High and accurate results
CN106770873BInactive Publication Date: 2019-02-19FOURTH MILITARY MEDICAL UNIVERSITY
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Patent Information

Authority / Receiving Office
CN · China
Patent Type
Patents(China)
Current Assignee / Owner
FOURTH MILITARY MEDICAL UNIVERSITY
Publication Date
2019-02-19
Estimated Expiration
Not applicable · inactive patent

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Abstract

The invention provides a bladder cancer diagnosis marker which comprises inosine, N-acetyl-N-2-formyl-5-methoxy kynurenine and phosphatidylserine (O-18: 0 / 0: 0). A diagnosis index for a low-level bladder cancer and a high-level bladder cancer can be built through combination of human serum inosine, N-acetyl-N-2-formyl-5-methoxy kynurenine and phosphatidylserine (O-18: 0 / 0: 0), and accurate and fast diagnosis is carried out on the bladder cancer. The invention further provides application of the bladder cancer diagnosis marker in preparation of the bladder cancer diagnosis kit. In addition, the invention further provides the bladder cancer diagnosis kit. The bladder cancer diagnosis marker is capable of accurately judging the bladder cancer and accurately distinguishing the low-level bladder cancer from the high-level bladder cancer; the accuracy of the diagnosis result is high; and the quantizable, objective and sensitive clinical diagnosis index is provided for diagnosis of the bladder cancer.
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Description

technical field

[0001] The invention belongs to the technical field of biomedicine, and in particular relates to a bladder cancer diagnostic marker, its application and a diagnostic kit. Background technique

[0002] Bladder cancer is the most common malignant tumor in the urinary system in my country. Bladder cancer can be divided into low-grade and high-grade bladder cancer according to how different the tumor cells are from normal cell structures. A tumor is considered high-grade or HG if it is characterized by its high invasiveness and high degree of malignancy to invade other tissues, or low-grade or LG when it is characterized by its low degree of malignancy or invasive potential tumor. Low-grade bladder cancer can usually be cured by endoscopic local excision, while high-grade bladder cancer usually requires radical cystectomy because of its high degree of malignancy, easy recurrence, and distant metastasis. Currently, cystoscopy and urine exfoliation cytology are ...

Claims

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