Composition used for preventing and treating ruminant disease of ruminant in perinatal period and fatty liver disease

A technology for ruminants and compositions, which is applied in the direction of drug combinations, metabolic diseases, medical preparations containing active ingredients, etc., can solve the problems of no effective method for prevention, failure to prevent cow ketosis, failure to pass through the rumen, etc., to improve prevention and therapeutic effect, increase biological potency, and sustainable development

Active Publication Date: 2017-06-09
BEIJING YAHE NUTRITIVE HIGH TECH CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0007] At present, ketosis in dairy cows can only be treated by intravenous injection of glucose. Usually, the cows need to be injected continuously for 5 days, which is very inconvenient.
However, there is no effective way to prevent this disease. Adding glucose directly to the diet cannot prevent cow ketosis, because glucose directly added to the diet will be destroyed by rumen microorganisms in the rumen and cannot pass through the rumen.

Method used

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  • Composition used for preventing and treating ruminant disease of ruminant in perinatal period and fatty liver disease
  • Composition used for preventing and treating ruminant disease of ruminant in perinatal period and fatty liver disease
  • Composition used for preventing and treating ruminant disease of ruminant in perinatal period and fatty liver disease

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Experimental program
Comparison scheme
Effect test

Embodiment approach

[0033] 1. Experimental animals and groups

[0034] In the intensive 1,000-head pasture, according to the principle of similar age, body condition, and parity, 28 healthy dairy cows with similar expected delivery dates were selected, including 21 cows in the experimental group, divided into groups I, II, and III, with 7 cows in each group. There were 7 cows in the control group; the cows in the experimental group and the control group were fed normally according to the NRC feeding standard before and after delivery.

[0035] 2. Specific feeding situation:

[0036] Group I, Group II, and Group III cows were fed with the above-mentioned composition 1, composition 2, and composition 3 respectively. Specifically, the cows in the experimental group were fed with the above-mentioned corresponding composition every day at the same time point from 0d to 21 days after delivery. The doses were 430 g / head·day, 365 g / head·day, and 288 g / head·day respectively, and the cows in the control g...

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Abstract

The invention discloses a composition used for preventing and treating ruminant disease of ruminant in perinatal period and fatty liver disease. The composition comprises rumen protected glucose, rumen protected choline and/or rumen bypass protected niacin; the ruminant includes dairy cattle, beef cattle and sheep. By the arrangement, preventing and treating effect of the composition on the ruminant disease of the dairy cattle in the perinatal period and the fatty liver disease can be effectively improved, occurrence of postpartum weight loss is reduced, nonreturn rate is increased, and milk yield is increased.

Description

technical field [0001] The invention relates to the field of preventing and treating perinatal ruminant diseases, in particular to a composition for preventing and treating perinatal ruminant ketosis and fatty liver disease. Background technique [0002] After calving, due to the sharp increase in milk production, the need for energy, especially for glucose, continues to increase, while the rumen-passing carbohydrates provided by the diet for the synthesis of glucose are far from sufficient, resulting in a drop in blood sugar and changes in sugar in the body. The biogenesis mechanism is activated, body protein is used, and body fat is lipolyzed, leading to ketosis or subclinical ketosis and fatty liver disease. [0003] Ketosis is a disorder of sugar and fat metabolism in dairy cows, resulting in the accumulation of large amounts of ketone bodies (including β-hydroxybutyric acid (BHBA), acetoacetate and acetone, mainly β-hydroxybutyric acid) in the blood, which are produced ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K31/7004A61K31/455A61K31/14A61P3/08A61P3/00A61P1/16
CPCA61K31/14A61K31/455A61K31/7004A61K2300/00
Inventor 刘春海陶春卫董秀君
Owner BEIJING YAHE NUTRITIVE HIGH TECH CO LTD
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