Method for preparing freeze-dried preparation in any shape and product thereof
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A freeze-dried preparation and a technology of any shape, which is applied in the field of preparing freeze-dried preparations of any shape and their products, and can solve the problems of no demoulding, single preparation shape, single shape, etc.
Pending Publication Date: 2017-06-13
董玲
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[0004] Most of the lyophilized excipients on the market are single in form, and the molds used are traditional moulds, i.e. common groove molds. This traditional lyophilized excipient and its preparation method have the following disadvantages:
[0005] (1) The shape of the preparation is single. The reason is that the shape of the mold is fixed, and it can only be demoulded without demoulding or from one direction. No demoulding means that it is molded directly in a certain shape of packaging material, so it is rare to be spherical, Due...
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Embodiment 1
[0076] A. Prepare a solution by mixing 1 liter of water, 200 g of VC powder, and 40 g of pullulan to form liquid 1;
[0077] B. Freeze liquid 1, and spray it with liquid nitrogen during the freezing process to form snowflake-like ice powder, which is component 2;
[0078] C. Put component 2 into a cylindrical mold for quantification to form quantitative component 4, and apply a certain pressure to press into component 4;
[0079] D. Freeze-dry the compressed component 4 to form freeze-dried VC essence powder for external use 12 .
Embodiment 2
[0081] A. Add 1 liter of VE 100g, Tween 30g, mannitol 50g, carbomer 30g, and triethanolamine 50ml to form an emulsion to form liquid 1;
[0082] B. Freeze liquid 1, and during the freezing process, spray it with liquid nitrogen to form ice crystals, and further enter the low-temperature pulverizer for crushing until it passes through a 200-mesh sieve, which is component 2;
[0083] C. Put component 2 into an ellipsoidal mold for quantification to form quantitative component 4, and apply a certain pressure to press into component 4;
[0084] D. Freeze-dry the compressed component 4 to form a freeze-dried VE milk solid ointment 12 .
Embodiment 3
[0086] A. Add 200g of nano-grade pearl powder and 30g of xanthan gum to 1 liter of water to make a suspension, and disperse evenly to form liquid 1;
[0087] B. Freeze liquid 1, and after freezing, use a low-temperature pulverizer to physically crush it to form ice particles, which is component 2;
[0088] C, component 2 is packed into hemispherical mold quantitatively, forms quantitative component 4;
[0089] D. Freeze-dry component 4 to form a freeze-dried oral pearl powder health food.
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Abstract
The invention relates to a method for preparing a freeze-dried preparation in any shape and a product made according to the method, and particularly relates to a preparation method of a freeze-dried preparation which is prepared and obtained through sufficiently agitating and making a freeze-dried preparation stock solution or freeze-dried preparation water into a smoothie during refrigeration, capably further mixing raw and auxiliary materials into the smoothie and then loading an obtained mixture into a certain mold to carry out freeze drying, is in any shape and mainly contains an active component and a binder, and a product made according to the method.
Description
technical field [0001] The present invention relates to a kind of method for preparing the freeze-dried preparation of any shape and the product made according to the method, particularly relate to a kind of smoothie that can be made by fully stirring water or the stock solution of freeze-dried preparation when freezing, and can further make The preparation method of the freeze-dried preparation mainly containing active ingredients and binders prepared by mixing the raw and auxiliary materials into a smoothie, and then filling it into a certain mold for freeze-drying, and the product obtained by this method . Background technique [0002] Freeze-drying excipient technology refers to adding a skeleton support agent and a binder to a flowable liquid, semi-solid or solid active ingredient, or the flowable liquid, semi-solid or solid itself contains a binder and a skeleton The support agent is then poured into a molding mold and shaped by a freeze-drying process. The preparatio...
Claims
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Application Information
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