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Cordyceps sinensis extract contained ginger phenol complex stabilizer

A composite stabilizer, Cordyceps sinensis technology, applied in the directions of pharmaceutical combinations, medical preparations containing active ingredients, anti-inflammatory agents, etc., can solve problems such as difficulty in the stability of gingerol, and achieve easy preparation, low cost, and increased application. range effect

Inactive Publication Date: 2017-07-21
HUBEI UNIV OF ARTS & SCI
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] But the stability of gingerol has always been a well-known problem, ensuring that the activity of gingerol does not change over time is a big problem

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0031] 1. A gingerol composite stabilizer containing Cordyceps sinensis extract, the preparation method is, after absorbing 10% alcohol with lotus seed powder, mixing lotus seed powder with white dextrin, Cordyceps sinensis extract, gingerol, lotus root powder to obtain the product , wherein, the weight of each of the above raw materials is: white dextrin 10g, Cordyceps sinensis extract 1g, gingerol 25g, lotus root powder 5g, lotus seed powder 5g, 10% alcohol 1g.

[0032] The preparation method of above-mentioned Cordyceps sinensis extract is as follows:

[0033] a. Dry and pulverize Cordyceps sinensis, add 10% ethanol aqueous solution, the total weight of the ethanol solution is twice the weight of the dried and pulverized Cordyceps sinensis, heat reflux extraction at 50°C for 20 minutes, and filter to obtain the extract;

[0034] b. Extracting the above extract with ethyl acetate to obtain the extract;

[0035] c. Carry out column chromatography on the above-mentioned extra...

Embodiment 2

[0040] 1. A gingerol composite stabilizer containing Cordyceps sinensis extract, the preparation method is, after absorbing 10% alcohol with lotus seed powder, mixing lotus seed powder with white dextrin, Cordyceps sinensis extract, gingerol, lotus root powder to obtain the product , wherein, the weight of each of the above raw materials is: white dextrin 15g, Cordyceps sinensis extract 1.5g, gingerol 30g, lotus root powder 7.5g, lotus seed powder 7.5g, 10% alcohol 1.5g.

[0041] The preparation method of above-mentioned Cordyceps sinensis extract is as follows:

[0042] a. Dry and pulverize Cordyceps sinensis, add 15% ethanol aqueous solution, the total weight of the ethanol solution is 2.5 times of the weight of the dried and pulverized Cordyceps sinensis, leaching under reflux at 55° C. for 25 minutes, and filter to obtain an extract;

[0043] b. Extracting the above extract with ethyl acetate to obtain the extract;

[0044] c. Carry out column chromatography on the above-...

Embodiment 3

[0049] 1. A gingerol composite stabilizer containing Cordyceps sinensis extract, the preparation method is, after absorbing 10% alcohol with lotus seed powder, mixing lotus seed powder with white dextrin, Cordyceps sinensis extract, gingerol, lotus root powder to obtain the product , wherein, the weight of each of the above-mentioned raw materials is: white dextrin 20g, Cordyceps sinensis extract 2g, gingerol 35g, lotus root starch 10g, lotus seed powder 10g, 10% alcohol 2g.

[0050] The preparation method of above-mentioned Cordyceps sinensis extract is as follows:

[0051] a. Dry and pulverize Cordyceps sinensis, add 20% ethanol aqueous solution, the total weight of the ethanol solution is 3 times the weight of the dried and pulverized Cordyceps sinensis, leaching under reflux at 60°C for 30 minutes, and filter to obtain the extract;

[0052] b. Extracting the above extract with ethyl acetate to obtain the extract;

[0053] c. The above-mentioned extract is subjected to col...

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PUM

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Abstract

The invention relates to the field of ginger phenol processing, in particular to a cordyceps sinensis extract contained ginger phenol complex stabilizer. The preparation process includes that 10% of alcohol is adsorbed through lotus seed powder, the product is obtained by evenly mixing the lotus seed powder with white dextrin, the cordyceps sinensis extract, the ginger phenol and lotus root starch, and stabilization time of the ginger phenol is prolonged. Development of new products containing the ginger phenol can be promoted through preparation and utilization of the ginger phenol stabilizer, and use range of ginger phenol substances in food industry and pharmaceutical industry is increased.

Description

[0001] (—) Technical field [0002] The invention relates to the field of gingerol processing, in particular to a gingerol composite stabilizer containing Cordyceps sinensis extract. [0003] (2) Background technology [0004] Gingerol includes two types of single aromatic ring and double aromatic ring heptane. Single aromatic ring gingerol includes 6-gingerol, 8-gingerol, 10-gingerol, 12-gingerol, methyl-6-gingerol and other ingredients. The bisarylcycloheptane gingerols also include many components, and the structural difference is mainly due to the different substituents of the aromatic rings. So far, there are more than 10 clear gingerols. The properties and structures of these components are similar. Among the molecular structures Both have c3-carbonyl and c5-hydroxyl, which makes the chemical properties of gingerol extremely unstable. For example, under acidic conditions, the active hydrogen of C4 is easily dehydrated with the hydroxyl of C5 to form gingerol. The length ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/068A61K31/12A61K47/69A61K47/46A61P7/02A61P39/06A61P35/00A61P9/04A61P9/02A61P3/06A61P9/10A61P1/00A61P1/16A61P29/00A61P11/14A61P1/08A61P25/00A61P33/00A61P31/00
CPCA61K31/12A61K36/068A61K47/46A61K2236/333A61K2236/53A61K2236/55A61K2300/00
Inventor 阎华于博李云捷汤尚文李玉奇吴进菊刘传菊李欢欢张火云黄升谋
Owner HUBEI UNIV OF ARTS & SCI
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