HIV-1 (human immunodeficiency virus-1) integrase inhibitor tablet and preparation method thereof

An integrase inhibitor, HIV-1 technology, applied in pill delivery, antiviral agents, pharmaceutical formulations, etc., to achieve the effects of simple preparation process, high dissolution rate, and portability
CN107028902AInactive Publication Date: 2017-08-11TIANJIN INT JOINT ACADEMY OF BIOTECH & MEDICINE
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Patent Information

Authority / Receiving Office
CN · China
Current Assignee / Owner
TIANJIN INT JOINT ACADEMY OF BIOTECH & MEDICINE
Publication Date
2017-08-11
Estimated Expiration
Not applicable · inactive patent

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Abstract

The invention provides an HIV-1 (human immunodeficiency virus-1) integrase inhibitor tablet and a preparation method thereof. The preparation method includes the steps: mixing an HIV-1 integrase inhibitor HIV-A5 with pharmaceutically acceptable auxiliary materials; pressing the materials to prepare the HIV-1 integrase inhibitor tablet. The method is simple in preparation process, mechanical in production, high in automation degree, large in output and low in cost, and the prepared HIV-1 integrase inhibitor tablet is high in dissolubility, short in disintegration time, stable in quality and convenient to carry, transport and store and is a solid preparation.
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Description

technical field

[0001] The invention relates to the field of pharmacy, in particular to an HIV-1 integrase inhibitor tablet and a preparation method thereof. Background technique

[0002] AIDS (acquired immunodeficiency syndrome, referred to as AIDS) has developed into a global disease since it was first diagnosed in the United States in 1981. So far, AIDS has become one of the most important epidemic diseases in the world. According to the latest statistics from UNAIDS, there are 35.3 million people living with AIDS worldwide, and 1.6 million people died of AIDS-related diseases in 2012. In 1983, Montgnier Bare-Sinoussi and others confirmed that the pathogen of AIDS is human immunodeficiency virus (human immunodeficiency virus, referred to as HIV), by killing or destroying the human immune system, a series of opportunistic infections and tumors are concurrent, and severe cases can lead to die. The replication cycle of HIV is divided into adsorption, penetration, uncoatin...

Claims

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