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Composition for treating non-small cell lung cancer and application of ginsenoside F4

A technology of non-small cell lung cancer and ginsenosides, applied in the field of biomedicine, can solve the problems of serious, lung injury, radiation pneumonitis, side effects, etc., and achieve the effect of good effect and growth inhibition.

Inactive Publication Date: 2017-08-29
华瑞(福建)生物科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] (1) Non-small cell lung cancer patients lack typical clinical manifestations in the early stage and cannot be diagnosed in time. About 70% of the patients are already in the advanced stage when they are diagnosed and cannot be operated on.
Even if the patient meets the surgical standard, the probability of recurrence after surgery is still relatively high;
[0006] (2) Chemotherapy regimens are administered based on experience. This homogeneous treatment often has great blindness, and the side effects of chemotherapy drugs are obvious, which greatly damages the autoimmune system and is prone to drug resistance. void after use;
[0007] (3) The side effects of radiotherapy are large, and it is easy to cause lung injury and radiation pneumonitis;
Although these targeted drugs can alleviate tumor progression or improve the quality of life to a certain extent, they also have serious side effects during treatment. Many patients cannot bear the pain caused by side effects and stop taking drugs

Method used

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  • Composition for treating non-small cell lung cancer and application of ginsenoside F4
  • Composition for treating non-small cell lung cancer and application of ginsenoside F4

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0025] A kind of ginsenoside F 4 The preparation method of traditional Chinese medicine prescription granules, the raw materials are as follows: Ginsenoside F 4 100g; Ganoderma lucidum extract 100g; Astragalus extract 200g; Lycium barbarum extract 500g; Starch 1000g;

[0026] Ginsenoside F 4 , Ganoderma lucidum extract, Astragalus extract, Lycium barbarum extract and starch were mixed evenly, granulated in a wet granulator, dried and bagged; finally, 190 bags of granules were prepared; 10g per bag, three times a day, every day 1 bag at a time.

Embodiment 2

[0028] A kind of ginsenoside F 4 The preparation method of the capsule, raw material is as follows: Ginsenoside F 4 100g; microcrystalline cellulose 1000g; povidone K30 300g; croscarmellose sodium 400g; magnesium stearate 100g;

[0029] After the above-mentioned raw and auxiliary materials are mixed evenly, 4750 hard capsules, each 400 mg, are prepared through the capsule preparation process.

Embodiment 3

[0031] A kind of ginsenoside F 4 The preparation method of the tablet, raw material is as follows: Ginsenoside F 4 100g; Ganoderma lucidum extract 100g; Lactose 1000g; Pregelatinized starch 400g; Magnesium stearate 100g;

[0032] Mix the above-mentioned raw and auxiliary materials evenly, granulate, dry, granulate, and compress to prepare 4250 tablets, each 400 mg.

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Abstract

The invention relates to the field of biomedicine, in particular to a composition for treating non-small cell lung cancer and application of ginsenoside F4 in the preparation of the composition for treating non-small cell lung cancer. The composition and the application have the advantages that the ginsenoside F4 is a rare ginsenoside, having a very low content in natural ginseng; it is discovered by the inventor that the ginsenoside F4 can treat non-small cell lung cancer; cellular and animal experiments and clinical tests prove that the ginsenoside F4 is capable of inhibiting the growth of non-small cell lung cancer, with better effect than ginsenoside Rg3; the composition may act as a potential drug for treating non-small cell lung cancer, and the drug is efficient and nontoxic and is suitable for long-term administration.

Description

technical field [0001] The invention relates to the field of biomedicine, in particular to a composition for treating non-small cell lung cancer and ginsenoside F 4 Application in preparation of composition for treating non-small cell lung cancer. Background technique [0002] In the 21st century, the mortality rate of malignant tumors has been increasing year by year, and it is still an important disease that affects human life and health. The mortality rate ranks second among all causes of death, second only to cardiovascular diseases. Classified by disease type, among all the causes of death in 2004, lung cancer ranked 8th, and it is expected to rise to 6th in 2030, ranking first among various cancers. At the same time, the incidence of lung cancer has always been at the top of the cancer spectrum in my country. From 2000 to 2005, the number of new cases of lung cancer in my country increased by 120,000, and the annual growth rate was 26.3%. Lung cancer is the most com...

Claims

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Application Information

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IPC IPC(8): A61K31/704A61K36/815A61K36/074A61P35/00
CPCA61K31/704A61K36/074A61K36/481A61K36/815A61K2300/00
Inventor 胡堃吴帼英林广勤崔侠
Owner 华瑞(福建)生物科技有限公司