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Heat-clearing buccal tablet and preparation method thereof

A buccal tablet and granule technology, which is applied in the field of medicine, can solve the problems of slow relief of oral symptoms, inability to make patient compliance, and good buccal tablets, etc., to achieve relief of oral symptoms, good compliance, and good taste Effect

Active Publication Date: 2017-09-26
HANDAN COLLEGE
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, getting angry is often accompanied by oral problems, sore throat, toothache, and oral ulcers. Swallowing medicines can slowly relieve oral symptoms, and Coptis chinensis has a bitter taste, so it cannot be made into lozenges that allow patients to comply

Method used

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  • Heat-clearing buccal tablet and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0027] A heat-clearing buccal tablet, the key technical point of which is that it includes an upper tablet, a middle tablet and a lower tablet, and the specific prescription is as follows:

[0028] Top layer:

[0029] Taihang Chrysanthemum Extract 3g;

[0030] Xylitol 2.5g;

[0031] Lactose 13.9g;

[0032] Vitamin C 0.4 g;

[0033] Magnesium Stearate 0.2g.

[0034] Middle slice:

[0035] Coptis chinensis extract 3.5 g;

[0036] Honey pomelo juice concentrate 5.5 g;

[0037] Sodium alginate 8 g;

[0038] Sorbitol 0.9 g;

[0039] Isomalt 11.8g;

[0040] Magnesium stearate 0.3g.

[0041] Lower layer:

[0042] Taihang Chrysanthemum Extract 3g;

[0043] Xylitol 2.5g;

[0044] Lactose 13.9g;

[0045] Vitamin C 0.4 g;

[0046] Magnesium Stearate 0.2g.

[0047] The preparation method is as follows:

[0048] (1) Preparation of upper and lower particles

[0049] Mix Taihang Chrysanthemum extract, xylitol, lactose and vitamin C evenly, pulverize, pass through a 100-mesh...

Embodiment 2

[0057] A heat-clearing buccal tablet, the key technical point of which is that it includes an upper tablet, a middle tablet and a lower tablet, and the specific prescription is as follows:

[0058] Top layer:

[0059] Taihang Chrysanthemum Extract 4g;

[0060] Xylitol 3g;

[0061] Lactose 12g;

[0062] Vitamin C 0.6g;

[0063] Magnesium Stearate 0.4g.

[0064] Middle slice:

[0065] Coptidis extract 4.5g;

[0066] Honey pomelo juice concentrate 5.3g;

[0067] Sodium alginate 7g;

[0068] Isomalt 12g;

[0069] Magnesium stearate 0.3g;

[0070] Sorbitol 0.9g.

[0071] Lower layer:

[0072] Taihang Chrysanthemum Extract 4g;

[0073] Xylitol 3g;

[0074] Lactose 12g;

[0075] Vitamin C 0.6g;

[0076] Magnesium Stearate 0.4g.

[0077] The preparation method is as follows:

[0078] (1) Preparation of upper and lower particles

[0079] Mix Taihang Chrysanthemum extract, xylitol, lactose and vitamin C evenly, pulverize, pass through a 100-mesh sieve, add 40% ethanol aq...

Embodiment 3

[0087] A heat-clearing buccal tablet, the key technical point of which is that it includes an upper tablet, a middle tablet and a lower tablet, and the specific prescription is as follows:

[0088] Top layer:

[0089] Taihang Chrysanthemum Extract 2g;

[0090] Xylitol 3g;

[0091] Lactose 14g;

[0092] Vitamin C 0.4 g;

[0093] Magnesium Stearate 0.6g.

[0094] Middle slice:

[0095] Coptis chinensis extract 4 g;

[0096] Honey pomelo juice concentrate 7.5 g;

[0097] Sodium alginate 8 g;

[0098] Sorbitol 1.2 g;

[0099] Isomalt 9 g;

[0100] Magnesium stearate 0.3g.

[0101] Lower layer:

[0102] Taihang Chrysanthemum Extract 2g;

[0103] Xylitol 3g;

[0104] Lactose 14g;

[0105] Vitamin C 0.4 g;

[0106] Magnesium Stearate 0.6g.

[0107] The preparation method is as follows:

[0108] (1) Preparation of upper and lower particles

[0109] Mix Taihang Chrysanthemum extract, xylitol, lactose and vitamin C evenly, pulverize, pass through a 100-mesh sieve, add ...

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Abstract

The invention relates to a heat-clearing buccal tablet and a preparation method thereof. The heat-clearing buccal tablet is technically characterized by comprising an upper layer tablet, a middle layer tablet and a lower layer tablet, wherein the upper layer tablet and the lower layer tablet respectively comprise flos opisthopapi taihangensis extract, xylitol, lactose, vitamin C and magnesium stearate; the middle layer tablet comprises rhizoma coptidis extract, honey pomelo juice concentrate, sodium alginate, sorbitol, isomaltitol and magnesium stearate. The heat-clearing buccal tablet has the advantages that the mouth feel is good, the compliance of a patient is good, the effects of clearing heat and reducing internal heat are realized, and the internal fire symptom of an oral cavity is relieved.

Description

technical field [0001] The invention relates to the field of medicine, in particular to a heat-clearing buccal tablet and a preparation method thereof. Background technique [0002] "Shanghuo" is a folk saying, also known as "hot air", which can be explained from the theory of traditional Chinese medicine and belongs to the category of heat syndrome in traditional Chinese medicine. Chinese medicine believes that the human body's yin and yang are out of balance, and if the internal fire is strong, it will get angry. Therefore, the so-called "fire" refers to certain heat symptoms in the body, and getting angry is the internal heat syndrome that occurs after the imbalance of yin and yang in the human body. "Get angry" is more likely to occur in dry climate and continuous hot and humid weather. It is generally believed that "fire" can be divided into two categories: "real fire" and "virtual fire". The common clinical types of "fire" are "heart fire" and "liver fire". The solu...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/752A61K47/46A61K9/20A61P1/02A61P11/04A61P29/00
CPCA61K9/0056A61K9/2068A61K9/209A61K36/287A61K36/718A61K36/752A61K2236/31A61K2236/333A61K2236/39A61K2236/51A61K2236/53A61K2300/00
Inventor 葛水莲陈建中
Owner HANDAN COLLEGE
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