Nutrient composition composed of vitamin D, vitamin K and folic acid

A vitamin and composition technology, applied in the field of making nutritional supplements or health food, can solve the problems of enzyme activity decline, consumers’ difficulty in choosing, and many ingredients, so as to achieve the effect of ensuring efficacy and assisting in the prevention of cardiovascular diseases

Active Publication Date: 2017-10-10
SHENZHEN AUSA PHARM CO LTD +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Folic acid deficiency can lead to deoxyribonucleic acid (DNA) synthesis disorder, and then cell division and reproduction are hindered
The polymorphism of methylenetetrahydrofolate reductase (MTHFR) gene may lead to the relative deficiency of folic acid utilization in Chinese population: MTHFR is the key to the reduction of 5,10-methylenetetrahydrofolate to 5-methyltetrahydrofolate Enzyme, such as gene mutation, the enzyme activity will be significantly reduced, affecting the activation of exogenous folic acid into 5-methyltetrahydrofolate, and the transmission of one-carbon unit is blocked, so Hcy cannot be smoothly converted into methionine, resulting in hyperHcyemia
[0007] At present, there are many multivitamin products on the market, but due to the large number of ingredients and the low content of each element, they lack pertinence, making it difficult for consumers to choose, and the actual health care effect is still unpredictable

Method used

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  • Nutrient composition composed of vitamin D, vitamin K and folic acid
  • Nutrient composition composed of vitamin D, vitamin K and folic acid
  • Nutrient composition composed of vitamin D, vitamin K and folic acid

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0031] Embodiment 1: the tablet preparation (1000 pieces amount) of health food of the present invention

[0032] formula:

[0033]

[0034] Preparation method: take povidone K30 and prepare an adhesive with 50% ethanol solution, then add vitamin D into the adhesive and stir evenly, and set aside. Separately take vitamin K, 5-methyltetrahydrofolate, sucralose and pregelatinized starch, mix and sieve, then add milk essence, carboxymethyl starch sodium, dextrin and mix, add the prepared adhesive containing vitamin D Prepare soft material, granulate with 24 mesh sieve, dry at 55°C for 2 hours, granulate with 24 mesh sieve, add magnesium stearate to mix, and press into tablets. The coating premix is ​​formulated into a solution, and the plain tablet is coated to obtain the health food tablet of the present invention.

Embodiment 2

[0035] Embodiment 2: the tablet preparation (1000 pieces amount) of health food of the present invention

[0036] formula:

[0037]

[0038] Preparation method: take povidone K30 and prepare an adhesive with 50% ethanol solution, then add vitamin D into the adhesive and stir evenly, and set aside. Separately take vitamin K, folic acid, sucralose and pregelatinized starch, mix and sieve, then add milk essence, carboxymethyl starch sodium, dextrin and mix, add the prepared soft material containing vitamin D adhesive, 24 mesh Sieve and granulate, dry at 55°C for 2 hours, sieve and granulate with 24 mesh, add magnesium stearate to mix, and press into tablets. The coating premix is ​​formulated into a solution, and the plain tablet is coated to obtain the health food tablet of the present invention.

[0039] In order to prove that the health care product of the present invention has the effect of preventing cardiovascular and cerebrovascular diseases, we designed the following...

Embodiment 3

[0051] Embodiment 3: the soft capsule preparation (1000 amount) of health food of the present invention

[0052] formula:

[0053]

[0054]

[0055] Preparation method: add beeswax to soybean oil, heat at 50°C to dissolve the beeswax, place it at room temperature, add vitamin D, folic acid, and vitamin K to soybean oil to make a suspension, and set aside. In addition, gelatin, purified water, caramel color, and parabens are prepared into a glue solution, and the prepared suspension is pressed into pills by a pill press to make soft capsules. After shaping, pill washing and drying, it is prepared Obtain the soft capsule of health food of the present invention.

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PUM

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Abstract

The invention provides a nutrient composition. The nutrient composition is composed of 2-100 micrograms of vitamin D, 10-500 micrograms of vitamin K, 30-2000 micrograms of folic acid, and acceptable auxiliary materials for health foods. The nutrient composition provided by the invention is capable of accurately providing nutritional supplements to the middle aged and the elderly people so as to achieve the effects of protecting bone health and preventing cardiovascular disease as an auxiliary means.

Description

technical field [0001] The present invention relates to a nutrient composition, more precisely, the present invention relates to a nutrient composition for carrying out precise nutritional supplementation for people deficient in vitamin D, K and folic acid nutrients, and the nutrient composition is suitable for making nutritional supplements or Healthy food. Background technique [0002] Vitamin D is a fat-soluble vitamin. It is a sterol derivative. There are five compounds. Vitamin D2 and D3 are closely related to health. They exist in some natural foods. Cholesterol in the human body can be transformed after being irradiated by ultraviolet rays. for vitamin D. Vitamin D receptors exist in most tissues of the body, and many common diseases, including some common tumors, diabetes, Alzheimer's, cardiovascular disease and osteoporosis, are associated with vitamin D deficiency. Vitamin D deficiency has become a public health problem. Vitamin D is one of the essential substan...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A23L33/15A23L33/155
CPCA23V2002/00A23L33/15A23L33/155A23V2200/326A23V2200/306A23V2250/71A23V2250/7056A23V2250/714
Inventor 黄晓杰白洁于多徐希平
Owner SHENZHEN AUSA PHARM CO LTD
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