The use of a composition
A technology of composition and use, which is applied in the direction of drug combination, medical preparations with non-active ingredients, medical preparations containing active ingredients, etc., can solve the problem that the therapeutic effect is not as expected, and achieve the effect of inhibiting the growth of colorectal cancer cells
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preparation example 1
[0027] First, a polyacrylonitrile (PAN)-based activated carbon fiber cloth is provided, which has the following characteristics: a BET specific surface area of 1,100 m2 / g, and a carbon content of 80.7% by weight. Next, after soaking the fiber cloth in 0.0025M silver nitrate aqueous solution for 2 hours, the fiber cloth was heat-dried at 100° C. for 2 hours to make the silver nitrate adhere to the fiber cloth. Thermally decompose silver nitrate at 600°C in the presence of nitrogen for 1.5 hours to reduce it to silver particles and adhere to the fiber cloth. Afterwards, the fiber cloth was washed with water for 2 hours to remove free silver particles. Then, the fiber cloth and the silver particles attached thereto are heat-dried to remove moisture. Finally, the fiber cloth is ground to obtain a composition (such as figure 1 shown), this composition contains silver particles and activated carbon fiber powder loaded with silver particles, and the characteristics of this compos...
preparation example 2
[0029]First, a polyacrylonitrile-based activated carbon fiber cloth is provided, which has the following characteristics: a BET specific surface area of 1,100 m2 / g, and a carbon content of 80.7% by weight. Next, soak the fiber cloth in 0.0025M silver nitrate and 0.0025M copper nitrate aqueous solution for 2 hours, then heat dry the fiber cloth at 100° C. for 2 hours to make the silver nitrate and copper nitrate adhere to the fiber cloth. Thermally decompose silver nitrate and copper nitrate at 600°C in the presence of nitrogen for 1.5 hours to reduce them into silver particles and copper particles and attach them to the fiber cloth. Afterwards, the fiber cloth was washed with water for 2 hours to remove free silver particles and copper particles. Then, the fiber cloth and the silver particles and copper particles attached thereto are heat-dried to remove moisture. Finally, grind the fiber cloth to obtain a composition, which contains silver particles, copper particles, and ...
example 1
[0031] According to the International Organization for Standardization (International Organization for Standardization, ISO) 10993-5:2009 (E) specification, the composition of each example was cultured with mouse fibroblast L-929 for 24 hours to carry out toxicity analysis, and the dosage of the composition was 24mg / 1mL total volume of cells and culture medium. As shown in Table 1, the compositions of each example had no significant toxicity to normal cells at high doses.
[0032] The toxicity of the composition of table 1, each example gained to mouse fibroblast
[0033]
[0034] Analysis example 2
[0035] After the composition of Preparation Example 1 was cultured for 24 hours with human colon cancer cells HCT-116, Caco-2, or SW-480 or human colorectal cancer cells HT-29, MTT (3-(4,5-Dimethylthiazol- 2-yl)-2,5-diphenyltetrazolium bromide) analysis, wherein the dosage is shown in Table 2, which is the weight of the composition under the total volume of 1 mL of cells and...
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