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Preparation method of skin itch relieving disinfectant

A disinfectant and skin technology, which is applied in the field of preparation of skin antipruritic disinfectant, can solve the problems of skin cell damage, mosquito bites with no prevention effect, hidden dangers, etc., and achieve the effect of convenient storage and use, and excellent antibacterial effect

Inactive Publication Date: 2017-11-24
成都嘉宝祥生物科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0002] The external skin surface disinfectants currently used in the market are mainly prepared by directly dissolving chemical raw materials. The process is simple and the effect is single. It can only kill and inhibit various microorganisms. All or less have certain cell damage to the skin, and there are certain potential hidden dangers in continuous use. At the same time, there are no other auxiliary means to reduce skin damage; basically no preventive effect on preventing mosquito bites

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0012] Example 1: In step A, glyceryl monostearate, stearic acid, medical vaseline, and liquid paraffin are all of medical grade, and the heating temperature is heated to 85° C. in a water bath;

[0013] In step B, glycerin plays the role of enhancing protection and skin lubrication; sodium lauryl sulfate is a surfactant to improve curative effect; polyvinylpyrrolidone K30 has a molecular weight of 200,000, and its function is to enhance the water-soluble surface gloss of the matrix; Methyleneguanidine hydrochloride is the active ingredient and has antibacterial effect. At the same time, polyhexamethyleneguanidine hydrochloride can form a tiny film in water, which can isolate the skin from contact with the external environment and improve the curative effect when applied to the skin.

[0014] In step C, the water phase is slowly added to the oil phase to form an oil-in-water matrix, and the temperature is kept at 85° C., and the mixture is fully stirred evenly.

[0015] The ra...

Embodiment 2

[0016] Example 2: In step A, glyceryl monostearate, stearic acid, medical vaseline, and liquid paraffin are all of medical grade, and the heating temperature is heated to 90° C. in a water bath;

[0017] In step B, glycerin plays the role of strengthening protection and skin lubrication; sodium lauryl sulfate is a surfactant to improve curative effect; polyvinylpyrrolidone K30 has a molecular weight of 300,000, and its function is to enhance the water-soluble surface gloss of the matrix; Methyleneguanidine hydrochloride is the active ingredient and has antibacterial effect. At the same time, polyhexamethyleneguanidine hydrochloride can form a tiny film in water, which can isolate the skin from contact with the external environment and improve the curative effect when applied to the skin.

[0018] In step C, the water phase is slowly added to the oil phase to form an oil-in-water matrix, and the temperature is kept at 90°C, and the mixture is fully stirred evenly.

[0019] Rati...

Embodiment 3

[0020] Example 3: In step A, glyceryl monostearate, stearic acid, medical vaseline, and liquid paraffin are all of medical grade, and the heating temperature is heated to 88° C. in a water bath;

[0021] In step B, glycerin plays the role of enhancing protection and skin lubrication; sodium lauryl sulfate is a surfactant to improve curative effect; polyvinylpyrrolidone K30 has a molecular weight of 250,000, and its function is to enhance the water-soluble surface gloss of the matrix; Methyleneguanidine hydrochloride is an active ingredient and has antibacterial effect. At the same time, polyhexamethyleneguanidine hydrochloride can form a tiny film in water, and when applied to the skin, it can isolate the skin from contact with the external environment and improve the curative effect.

[0022] In step C, the water phase is slowly added to the oil phase to form an oil-in-water matrix, and the temperature is kept at 88° C., and the mixture is fully stirred evenly.

[0023] Ratio...

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Abstract

The invention discloses a preparation method of a skin itch relieving disinfectant, relating to the technical field of skin itch relieving and disinfecting. The preparation method comprises the following steps: A, heating glycerin monostearate, stearic acid, medical vaseline and liquid paraffin to 85-90 DEG C so that the glycerin monostearate, stearic acid, medical vaseline and liquid paraffin are fused into an oil phase; B, taking purified water, carrying out heating to 85 DEG C, respectively adding glycerol, sodium dodecyl sulfate, polyvinylpyrrolidone K30 and polyhexamethylene guanidine hydrochloride, and carrying out heating so that the glycerol, sodium dodecyl sulfate, polyvinylpyrrolidone K30 and polyhexamethylene guanidine hydrochloride are fused into a water phase; and C, slowly adding the water phase obtained in the step B to the oil phase obtained in the step A under stirring, thus obtaining ointment matrix. For the disinfectant prepared by adopting the preparation method disclosed by the invention, the fungus resisting and inhibiting curative effects are enhanced, the injury effect of the skin cells is reduced, and the purpose of preventing mosquito bites is achieved.

Description

technical field [0001] The invention relates to the technical field of skin antipruritic disinfection, in particular to a preparation method of a skin antipruritic disinfectant. Background technique [0002] The external skin surface disinfectants currently used in the market are mainly prepared by directly dissolving chemical raw materials. The process is simple and the effect is single. It can only kill and inhibit various microorganisms. All or less have certain cell damage to the skin, and there are certain potential hidden dangers in continuous use. At the same time, there are no other auxiliary means to reduce skin damage; basically there is no preventive effect on preventing mosquito bites. Contents of the invention [0003] In view of the above problems, the object of the present invention is to enhance the antibacterial and antibacterial curative effect, reduce the skin cell damage effect, and prevent mosquito bites. The technical scheme includes the following spe...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K9/06A61K31/785A61K47/12A61K47/14A61K47/06A61K47/10A61K47/20A61K47/32A61P31/04A61P17/02A61P17/04
CPCA61K31/785A61K9/0014A61K9/06A61K47/06A61K47/10A61K47/12A61K47/14A61K47/20A61K47/32
Inventor 马英祥姜晓筑
Owner 成都嘉宝祥生物科技有限公司
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