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Method for studying effects of reducing uric acid and reducing blood glucose of polygonum aubertii henry

A technology for lowering uric acid and blood sugar, which is applied in the field of medicine, can solve the problem of undiscovered effects of Polygonum vine on lowering uric acid and lowering blood sugar, and achieve the effect of reducing the level of SUA

Inactive Publication Date: 2017-12-12
QINGHAI UNIV FOR NATITIES
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  • Abstract
  • Description
  • Claims
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AI Technical Summary

Problems solved by technology

[0006] In the prior art, there is no relevant report on the effect of Polygonum vine on lowering uric acid and lowering blood sugar

Method used

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  • Method for studying effects of reducing uric acid and reducing blood glucose of polygonum aubertii henry
  • Method for studying effects of reducing uric acid and reducing blood glucose of polygonum aubertii henry
  • Method for studying effects of reducing uric acid and reducing blood glucose of polygonum aubertii henry

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Experimental program
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Embodiment Construction

[0052] The technical solutions of the present invention will be further described in detail below in conjunction with specific embodiments.

[0053] 1 Research on the effect of plants on reducing uric acid

[0054] 1.1 Animals

[0055] KM mice, SPF grade, body weight (20±2) g, purchased from Hunan Slack Jingda Experimental Animal Co., Ltd., animal qualification certificate number: SCXK (Xiang) 2013-0004), were raised in the Pharmacology Laboratory of Qinghai Nationalities University, The ambient temperature is 22-26°C, and the relative humidity is 55%-65%. The animals drank purified water, and the feed was maintained pellets for experimental mice, which were purchased from Hunan Slack Jingda Experimental Animal Co., Ltd., production certificate number: SCXK (Xiang) 2014-0002), and the experiment was carried out after one week of adaptation to the environment. Fasting without food and water for 12 hours before.

[0056] 1.2 Drugs

[0057] Polygonum vine stem extract freeze-...

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Abstract

The invention discloses a method for studying the effects of reducing uric acid and reducing blood glucose of polygonum aubertii henry. The method comprises the following steps: 1, preparing a test sample for reduction of the uric acid; 2, preparing a modeling agent for reduction of the uric acid; 3, preparing a positive drug for reduction of the uric acid; 4, modeling and administrating the drug for reducing the uric acid; 5, carrying out sampling and detecting about reduction of the uric acid; 6, carrying out statistical processing about reduction of the uric acid; 7, preparing a test sample for reduction of the blood glucose; 8, preparing a modeling agent for reduction of the blood glucose; 9, preparing a positive drug for reduction of the blood glucose; 10, establishing a diabetes model; 11, grouping animals and administrating the drug for reducing the blood glucose; 12, observing body weight changes before and after drug administration; 13, observing the changes of organ coefficients; 14, carrying out statistical processing about reduction of the blood glucose. The method lays a foundation for the study on the effects of reducing the uric acid and reducing the blood glucose of the polygonum aubertii henry.

Description

technical field [0001] The invention belongs to the technical field of medicine, and relates to a research method for the uric acid-lowering and blood-sugar-lowering effects of Polygonum vine. Background technique [0002] Polygonum aubertii Henry is a perennial semi-shrub. The stem is several meters long, suberect or twisted, the surface is reddish-purple, glabrous, solid, almost woody. Leaves clustered, thick, ovate or broadly triangular, 1-5 cm long, 0.5-3 cm wide, pointed at the top, heart-shaped or arrow-shaped at the base, wavy at the leaf margin, glabrous on both sides; thin petiole, 0.5-3 cm long 2.5 cm; inflorescences paniculate, axillary or terminal, with hairs on flower axis; bracts membranous, brown, funnel-shaped, apex acute, with 2-8 flowers in each bract; pedicel thin, 3-4 mm long, The lower part is jointed; the perianth is 5-parted, light pink or white, and the outer 3 pieces of the perianth are larger, the back is winged, the fruit is enlarged, and the bas...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): G01N33/15G01N33/66A61K36/704A61K31/515A61P3/10
CPCA61K31/515A61K36/704G01N33/66G01N33/94G01N2800/042G01N2800/52
Inventor 芦永昌钱帅张忠梅吕倩张弓史生辉王庶
Owner QINGHAI UNIV FOR NATITIES
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