Supercharge Your Innovation With Domain-Expert AI Agents!

Solution for treating contact lens and contact lens packaging system

A contact lens and packaging system technology, which is applied in the direction of lens cleaning composition, disinfection, inorganic non-surface active cleaning composition, etc., which can solve the problems of rough surface, hard lens, and easy dry lens surface

Active Publication Date: 2018-01-05
PEGAVISION CORP
View PDF6 Cites 5 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The comfort of wearing contact lenses is affected by many factors, and the uncomfortable feeling during wearing can be caused by the lens being too hard, insufficient moisture retention so that the lens surface is prone to dryness, the surface is rough, or the lens design is poor
For example, the moisture retention of traditional hydrogel lenses is generally good, but the material of silicone hydrogel lenses is more hydrophobic, and some hydrogel lenses will add UV blocking agents with hydrophobic properties. Therefore, silicone hydrogel lenses Lenses and lenses with UV blocking agents usually do not moisturize well, which is one of the reasons for the discomfort of lens wearers

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Solution for treating contact lens and contact lens packaging system
  • Solution for treating contact lens and contact lens packaging system
  • Solution for treating contact lens and contact lens packaging system

Examples

Experimental program
Comparison scheme
Effect test

experiment example 1

[0040] Experimental example 1: Preparation of homopolymer-poly[2-methacryloyloxyethylphosphorylcholine] (poly-MPC) with phosphorylcholine groups (Example 1A-1C):

[0041] In this experiment, 50g (0.169mole) of 2-methacryloyloxyethylphosphorylcholine (MPC) and 150mL of methanol (methanol) were added to a three-neck round-bottom flask, and the three-neck round-bottom flask was connected to reflux condensation reflux condenser. Nitrogen gas was introduced into the three-neck round bottom flask, and the MPC and methanol were stirred for 10 minutes until dissolved under the condition of being filled with nitrogen gas. Next, 0.25 g of azobisisobutyronitrile (AIBN) and 0.0398 g (0.509 mmole) of 2-mercaptoethanol were added and heated to 45° C. for 24 hours. AIBN is a polymerization initiator, which is connected to a carbon atom connected to a double bond in methacryloyloxyethyl of MPC to initiate free radical polymerization. 2-Mercaptoethanol is a polymer chain transfer agent (chai...

Embodiment 1A-1C

[0044] Examples 1A-1C have the structure of formula (II):

[0045]

[0046] In formula (II), m is a positive integer; and * is the starting point of the polymerization reaction, that is, the position where AIBN is connected.

experiment example 2

[0047] Experimental Example 2: Preparation of Copolymers with Phosphocholine Groups (Example 2A-2D):

[0048] The above method is also used for the preparation of the MPC copolymer, but different types of hydroxyalkyl methacrylate (hydroxyalkyl methacrylate) monomers are used for polymerization, and the amount of each reactant used is different. In detail, the preparation of MPC copolymer comprises adding 48g (0.163mole) of MPC, 12g (0.092mole) of hydroxyethyl methacrylate (2-hydroxyethyl methacrylate, HEMA) and 250mL of methanol into a three-neck round bottom flask , while the three-necked round-bottom flask was connected to a reflux condenser. Nitrogen was introduced into the three-necked round bottom flask, and the MPC, HEMA and methanol were stirred for 10 minutes under the condition of being filled with nitrogen until they were dissolved. Next, add 0.295g of AIBN and different amounts of 2-mercaptoethanol, respectively 0.932g (0.012mole), 0.2343g (3mmole), or 0.0469 (0.0...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

PropertyMeasurementUnit
number average molecular weightaaaaaaaaaa
number average molecular weightaaaaaaaaaa
number average molecular weightaaaaaaaaaa
Login to View More

Abstract

A solution for treating a contact lens and a contact lens packaging system are provided. The solution includes about 0.01 to about 1.0 parts by weight (pbw) of a polymer having phosphorylcholine groups, about 0.005 to about 0.05 pbw of a hydrophilic molecule, about 0.01 to about 1.0 pbw of an inorganic salt, and about 100 pbw of water. A number-average molecular weight of the polymer is about 4,000 to about 1,000,000 daltons. The polymer has a structure of formula (I): wherein, in formula (I), m is a positive integer, n is zero or a positive integer, and R is C 2 -C 12 alkyl group, or C 2 -C 12 hydroxyalkyl group. When n is a positive integer, m / n is greater than 1. Moreover, a number-average molecular weight of the hydrophilic molecule is about 10,000 to about 5,000,000 daltons. The hydrophilic molecule is hyaluronic acid (HA) or hyaluronate salt. The present invention provides a solution for treating a contact lens. After immersing the contact lens in the solution or using the solution to clean the contact lens, the treated lens would have relatively good wettability, thereby promoting the comfort level when wearing lens.

Description

technical field [0001] The invention relates to a solution for treating contact lenses and a packaging system for contact lenses, in particular to a solution containing polymers with phosphorylcholine groups and hydrophilic molecules. Background technique [0002] Soft contact lenses (soft contact lenses) are ubiquitous products on the market, which are packaged in polypropylene blister packages containing a preservation solution for sale. Preservation solution is usually saline buffer solution, in addition to sodium chloride and other inorganic salts, it also generally contains surfactants and / or humectants to maintain the moisture content of contact lenses and prevent contact lenses from sticking to the air bubbles. The inner surface of the structure. [0003] As far as the function of contact lenses is concerned, in addition to being able to correct visual acuity, their wearing comfort also has an important impact on consumers' preferences. Therefore, most contact lens ...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
Patent Type & Authority Applications(China)
IPC IPC(8): C11D7/60C11D7/36C11D7/26C11D7/08C11D7/10
CPCC11D3/0078C11D3/227C11D3/3784A61L12/08A61L12/086A61L12/14
Inventor 赖有进叶旻宗张汉宜张雅惠
Owner PEGAVISION CORP
Features
  • R&D
  • Intellectual Property
  • Life Sciences
  • Materials
  • Tech Scout
Why Patsnap Eureka
  • Unparalleled Data Quality
  • Higher Quality Content
  • 60% Fewer Hallucinations
Social media
Patsnap Eureka Blog
Learn More

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.

© 2025 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com