Radiology tumor imaging agent and preparation method thereof

A tumor imaging and radiology technology, applied in MRI/MRI contrast agents, pharmaceutical formulations, preparations for in vivo tests, etc., can solve problems such as insignificant effects, achieve no pain and side effects, and enhance uniform mixing degree, easy to prepare

Inactive Publication Date: 2018-01-12
杨润
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Although this technical document can reduce the background noise during magnetic resonance and improve the image contrast quality to a certain extent, its effect is not significant

Method used

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  • Radiology tumor imaging agent and preparation method thereof

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Effect test

Embodiment 1

[0018] A tumor imaging agent for radiology, consisting of the following raw materials in parts by weight: 60 parts of β-pinene resin, 45 parts of polyvinyl alcohol, 32 parts of hollow spherical hydroxyapatite, 30 parts of nano-gadolinium oxalate, 26 parts of titanium dioxide, 20 parts of cactus, 20 parts of rhubarb, 18 parts of roast chicken inner gold, 16 parts of rehmannia glutinosa, 14 parts of Scutellaria barbata, 14 parts of tangerine peel, and 10 parts of licorice.

[0019] The preparation method of the radiological tumor imaging agent comprises the following steps:

[0020] 1) Add 5 times the amount of deionized water to the cactus, rhubarb, broiled chicken neijin and Rehmannia glutinosa and decoct 3 times for 1.2 hours each time, and filter to obtain filtrate I and medicinal residues i; Scutellaria barbata, Dried tangerine peel and licorice root can be ground by a pulverizer and passed through a 60-mesh sieve to obtain fine powder A. After soaking fine powder A in filt...

Embodiment 2

[0024] A tumor imaging agent for radiology, consisting of the following raw materials in parts by weight: 77 parts of β-pinene resin, 58 parts of polyvinyl alcohol, 41 parts of hollow spherical hydroxyapatite, 37 parts of nano-gadolinium oxalate, 33 parts of titanium dioxide, 28 parts of cactus, 28 parts of rhubarb, 25 parts of broiled chicken inner gold, 21 parts of rehmannia, 17 parts of Scutellaria barbata, 17 parts of tangerine peel, and 14 parts of licorice.

[0025] The preparation method of the radiological tumor imaging agent comprises the following steps:

[0026] 1) Add 5 times the amount of deionized water to the cactus, rhubarb, broiled chicken neijin and rehmannia glutinosa and decoct 3 times for 1.3 hours each time, and filter to obtain filtrate I and medicinal residues i; Scutellaria barbata, Dried tangerine peel and licorice root can be crushed by a pulverizer and passed through a 60-mesh sieve to obtain a fine powder A. After soaking the fine powder A in the f...

Embodiment 3

[0030]A tumor imaging agent for radiology, consisting of the following raw materials in parts by weight: 95 parts of β-pinene resin, 70 parts of polyvinyl alcohol, 50 parts of hollow spherical hydroxyapatite, 44 parts of nano-gadolinium oxalate, 40 parts of titanium dioxide, 35 parts of cactus, 35 parts of rhubarb, 1 part of roast chicken, 25 parts of rehmannia, 19 parts of Scutellaria barbata, 19 parts of tangerine peel, and 17 parts of licorice.

[0031] The preparation method of the radiological tumor imaging agent comprises the following steps:

[0032] 1) Add 5 times the amount of deionized water to the cactus, rhubarb, broiled chicken neijin and Rehmannia glutinosa and decoct 3 times for 1.4 hours each time, and filter to obtain filtrate I and medicinal residues i; Dried tangerine peel and licorice root can be crushed by a pulverizer and passed through a 60-mesh sieve to obtain a fine powder A. After soaking the fine powder A in the filtrate I for 55 minutes, add 95% eth...

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Abstract

The invention discloses a radiology tumor imaging agent and a preparation method thereof, and belongs to the technical field of imaging agents. The radiology tumor imaging agent is prepared from the following raw materials: beta-polyterpene resin, polyvinyl alcohol, hollow spherical hydroxyapatite, nanometer gadolinium oxalate, titanium dioxide, radix et caulis opuntiae dillenii, rhei radix et rhizoma, roasted galli gigerii endothelium corneum, rehmanniae radix praeparata, scutellariae barbatae herba, pericarpium citri reticulatae and radix et rhizoma glycyrrhizae. According to the radiology tumor imaging agent and the preparation method thereof, four raw materials, i.e. the beta-polyterpene resin, the hollow spherical hydroxyapatite, the nanometer gadolinium oxalate and the titanium dioxide, are used as basic materials, and are mutually complemented by Chinese herbal ingredients used as auxiliaries to increase the cure rate of tumors and prevent a human body from extra damage caused by radiation. The tumor imaging agent has a certain therapeutic effect on the tumors, the tumor volume reduction rate is 82 to 85 percent, the radiation protection rate is 92.6 to 94.8 percent, pains and side effects are avoided, a relatively good therapeutic effect is achieved, and the symptoms are obviously improved after 40 to 45 days.

Description

technical field [0001] The invention belongs to the technical field of contrast agents, and in particular relates to a radiology tumor contrast agent and a preparation method thereof. Background technique [0002] Tumor refers to the neogrowth formed by the proliferation of local tissue cells in the body under the action of various tumorigenic factors, because this neogrowth is mostly in the form of space-occupying blocky protrusions, also known as neoplasm (neoplasm) . According to the cell characteristics of new organisms and the degree of harm to the body, tumors are divided into two categories: benign tumors and malignant tumors, and cancer is the general term for malignant tumors. Tumor is currently one of the major diseases that seriously threaten people's life safety. No matter at home or abroad, a large number of patients die of tumor every year. There are two modes of cancer treatment in my country, namely western medicine treatment and traditional Chinese medicin...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K49/06A61K49/08A61K49/12
Inventor 杨润
Owner 杨润
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