Micro-fluidic chemiluminescence detecting system for magnetic particles for detecting thyroid functions

A technology for chemiluminescence detection and thyroid function, applied in the field of medical testing, can solve the problems of tediousness, waste of reagents and reagent bottles, and increase of production costs

Active Publication Date: 2018-02-02
BEIJING ELCOTEQ BIO TECH
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  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

[0005] Total triiodothyronine (TT 3 ), total thyroxine (TT 4 ), free triiodothyronine (FT 3 ), free thyroxine (FT 4 ), Thyroid-stimulating hormone (TSH) belong to the gonad detection series, patients often need to detect a series of items in thyroid function, but in reality, all of them are individually packaged for a single test item, according to the current method, laboratory doctors need to test item by item Performing labor

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  • Micro-fluidic chemiluminescence detecting system for magnetic particles for detecting thyroid functions
  • Micro-fluidic chemiluminescence detecting system for magnetic particles for detecting thyroid functions
  • Micro-fluidic chemiluminescence detecting system for magnetic particles for detecting thyroid functions

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Embodiment Construction

[0056] The present invention will be further described below in conjunction with the accompanying drawings and specific embodiments, so that those skilled in the art can better understand the present invention and implement it, but the examples given are not intended to limit the present invention.

[0057] to combine Figure 1A~1B As shown, a microfluidic chemiluminescence detection system for magnetic particles used to detect thyroid function provided by the present invention includes a chassis 2 and an upper chip 1;

[0058] The upper layer chip 1 includes a sample loading area 10 located at the center of the upper layer chip 1 and 5 microfluidic reaction detection channels communicated with the sample loading area. A blood filter membrane (not shown in the figure), and a blood cap (not shown in the figure) may be covered on the anti-red blood cell filter membrane. The five microfluidic reaction detection channels are: total triiodothyronine (TT 3 ) Microfluidic reaction ...

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Abstract

The invention discloses a micro-fluidic chemiluminescence detecting system for magnetic particles for detecting thyroid functions. The system comprises a bottom plate and an upper chip, and the upperchip comprises a sample adding area in the center of the upper chip and five micro-fluidic reaction detecting channels communicated with the sample adding area, wherein the five micro-fluidic reactiondetecting channels include a total triiodothyronine micro-fluidic reaction detecting channel, a total thyroxine micro-fluidic reaction detecting channel, a free triiodothyronine micro-fluidic reaction detecting channel, a free thyroxine micro-fluidic reaction detecting channel and a thyroid stimulating hormone micro-fluidic reaction detecting channel. In application of the system, the bottom plate is arranged under the upper chip, and magnets which are permanent magnets or electromagnets are arranged at positions, corresponding to magnetic particle coating areas of the micro-fluidic reactiondetecting channels, of the bottom plate. By ingenious combination of the micro-fluidic technology and the magnetic particle chemiluminescence technology, quickness, high sensitivity and accuracy in quantitative detection of target substances are realized.

Description

technical field [0001] The invention belongs to the field of medical testing, in particular to a microfluidic chemiluminescent detection system of magnetic particles used for detecting thyroid function. Background technique [0002] In recent years, the field of bioanalysis technology has developed rapidly, and many important research directions have emerged. Microfluidic chip analysis technology is one of the most active ones, and has received extensive attention in both scientific research and application fields. As a new type of analysis and detection platform, microfluidic chips have the advantages of high throughput, integration, portability, easy operation, and low cost, and have been widely used in many fields. [0003] The current chemiluminescence detection is suitable for serum, and the sample needs to be centrifuged to obtain serum during the detection process, which is complex, tedious and time-consuming. Lack of sufficient elution to eliminate interference cau...

Claims

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Application Information

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IPC IPC(8): G01N21/76
CPCG01N21/76
Inventor 林斯
Owner BEIJING ELCOTEQ BIO TECH
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