Ethyl acetate based gradient extraction method for silymarin

An extraction method and ethyl acetate technology, applied in the production field of silymarin, can solve the problems of increasing extraction time cost and economic cost, influence of extraction purity of silymarin, inability to extract oil and so on, so as to improve overall efficiency and extraction purity, and ensure extraction purity. , the effect of prolonging the extraction time

Inactive Publication Date: 2018-02-06
内蒙古昶辉生物科技股份有限公司
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Problems solved by technology

The problem with this method is that after the milk thistle seeds are crushed, the oil cannot be completely extracted, which will have a certain impact on the subsequent extraction purity of silymarin; another technique is to shell the milk thistle seeds first, and then use water Silymarin is extracted from silymari...

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  • Ethyl acetate based gradient extraction method for silymarin
  • Ethyl acetate based gradient extraction method for silymarin
  • Ethyl acetate based gradient extraction method for silymarin

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Embodiment Construction

[0028] Aiming at the problems existing in the prior art, the method for extracting silymarin of the present invention uses a gradient extraction method in the extraction process to perform multiple parallel extractions of silymarin shells, which can increase the extraction rate of silymarin and ensure the extraction of silymarin. Purity and improved extraction efficiency.

[0029] In order to make the object, technical solution and advantages of the present invention clearer, the present invention will be described in detail below in conjunction with the accompanying drawings and specific embodiments.

[0030] figure 1 The flow chart of extracting silymarin for the present invention, as figure 1 As shown, the following specific implementation methods are included.

[0031] Step S10, adding the milk thistle seeds to the shelling machine for shelling;

[0032] The milk thistle seeds are sent to the shelling machine for shelling, the milk thistle seeds and the milk thistle she...

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Abstract

The invention relates to an extraction method for silymarin. The method is characterized by comprising steps as follows: silybum marianum seeds are added to a huller for hulling; silybum marianum hulls and ethyl acetate are added to pot group type gradient extraction equipment; the silybum marianum hulls are subjected to gradient extraction, and a primary extraction solution of silybum marianum isobtained; the primary extraction solution is concentrated, and a silybum marianum concentrated solution is obtained; aqueous alkali is added to the concentrated solution, and a mixed solution is stirred and left to stand for precipitation; precipitates are filtered, a product is dried, smashed and screened, and silymarin is obtained. According to the scheme, the gradient extraction is adopted, sothat extraction rate of silymarin is increased, and production energy consumption and production cost are reduced.

Description

technical field [0001] The embodiment of the present invention relates to a production method, in particular to a production method of silymarin. Background technique [0002] Silymarin is a mixture of flavonoid lignans derived from the seeds of the plant Silybum marianum in the family Asteraceae. Its main components include flavonoids such as silibinin, isosilibinin, dehydrosilibinin, silybinin and silybinin. Silymarin has the function of protecting the liver and promoting choleresis, and is mainly used for the treatment of liver diseases. Secondly, it also has obvious anti-lipid peroxidation, anti-radiation, scavenging free radicals, anti-gastric ulcer and other effects. It has good effects in reducing blood fat, preventing and treating atherosclerosis, preventing cerebral ischemia, and anti-platelet aggregation. Non-toxic, non-teratogenic and mutagenic. [0003] At present, there are two main extraction methods of silymarin, one is organic solvent extraction, and the ...

Claims

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Application Information

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IPC IPC(8): C07D407/04
CPCC07D407/04
Inventor 贾洪涛孙立姜鸿奇鞠向慧张成亮徐旭
Owner 内蒙古昶辉生物科技股份有限公司
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