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Compound preparation for treating non-allergic purpura caused by blood stasis blocking collaterals and its preparation method

A technology for allergic purpura and compound preparations, applied to medical preparations containing active ingredients, pharmaceutical formulas, blood diseases, etc., can solve the problems of lack of pertinence of drugs, side effects of drugs, unsatisfactory effects, etc., and improve bioavailability , Improve the dissolution rate, and help the absorption effect

Active Publication Date: 2020-07-14
天津市善济宏兴科技发展有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Although there are many kinds of drugs used clinically to treat non-allergic purpura, there are many factors leading to non-allergic purpura, and there are many types of non-allergic purpura. Therefore, these drugs are not targeted, and the course of treatment is relatively short. Longer, and some drugs have certain side effects or allergic reactions, so after taking it, the effect is not ideal for the treatment of non-allergic purpura caused by blood stasis.

Method used

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  • Compound preparation for treating non-allergic purpura caused by blood stasis blocking collaterals and its preparation method
  • Compound preparation for treating non-allergic purpura caused by blood stasis blocking collaterals and its preparation method
  • Compound preparation for treating non-allergic purpura caused by blood stasis blocking collaterals and its preparation method

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0012] The compound preparation for the treatment of non-allergic purpura caused by blood stasis and obstruction of collaterals provided in this example is made from the following pharmaceutical raw materials in terms of weight ratio:

[0013]

[0014] The preparation method of the compound preparation for treating non-allergic purpura caused by blood stasis blocking collaterals is to weigh and mix the above-mentioned medicinal raw materials according to the proportion, then add water to soak for 25 minutes, then decoct for 30 minutes, filter to remove slag. It can be made into the compound preparation for treating non-allergic purpura caused by blood stasis and blockage of collaterals.

[0015] In addition, the traditional Chinese medicine compound preparation can be prepared into granules, tablets, capsules, syrups, oral liquids, pills and ointments with commonly used pharmaceutical auxiliary materials.

Embodiment 2

[0017] The compound preparation for the treatment of non-allergic purpura caused by blood stasis and obstruction of collaterals provided in this example is made from the following pharmaceutical raw materials in terms of weight ratio:

[0018]

[0019] The preparation method is the same as in Example 1.

Embodiment 3

[0021] The compound preparation for the treatment of non-allergic purpura caused by blood stasis and obstruction of collaterals provided in this example is made from the following pharmaceutical raw materials in terms of weight ratio:

[0022]

[0023] The preparation method is the same as in Example 1.

[0024] The compound preparation for treating non-allergic purpura caused by blood stasis and blockage of collaterals provided by the invention is brown to brownish yellow; light in breath and slightly bitter in taste. In order to verify the therapeutic effect of this traditional Chinese medicine compound preparation, the present inventor has carried out systematic clinical observation on 350 patients suffering from blood stasis blocking collateral type non-allergic purpura by using the above-mentioned traditional Chinese medicine compound preparation, wherein 104 cases of patients aged 21-30, 31 - 145 cases aged 40, 101 cases aged 41-50, 150ml each time, 3 times a day, 120...

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PUM

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Abstract

Disclosed are a compound preparation for treating non-anaphylactoid purpura due to static blood obstructing the collaterals and a preparation method. The preparation is made from, according to a weight ratio, 9-24 of unprocessed rehmannia roots, 6-15 of Chinese angelica, 9-24 of peony roots, 6-15 of Sichuan lovage rhizome, 6-15 of peach seeds, 6-15 of safflowers, 6-15 of tree peony root barks, 6-15 of arnebia roots, 12-32 of herba agrimoniae, 9-24 of radix rubiae, 6-15 of rhizoma cyperi and 4-10 of raw liquorice roots. Efficient components in the raw medicines are extracted through water boiling, and activity of the efficient components is kept. In such manner, the dissolution rate of the efficient components in the medicines is greatly improved, which is beneficial for medicine absorption, and bioavailability of the medicines is improved. Further, the preparation is a pure traditional Chinese medicine compound preparation, doesn't have a toxic or side effect after a patient takes thepreparation for a long time, and is good in safety. Moreover, the preparation method is simple in process and convenient to operate.

Description

technical field [0001] The invention relates to a traditional Chinese medicine preparation and a preparation method thereof, in particular to a compound preparation and a preparation method thereof for treating non-allergic purpura caused by blood stasis blocking collaterals, which are made from traditional Chinese medicine. Background technique [0002] Nonallergic purpura is a hemorrhagic disease characterized by vascular abnormalities caused by various nonallergic etiologies and diseases. Clinically, it is mostly manifested as: skin purpura or ecchymosis, mucosal or visceral bleeding (rarely), Capillary fragility test can be positive, coagulation function, platelet count, platelet function and other tests are generally normal. There are many causes and diseases that cause non-allergic purpura, similar to the records of "muscle epistaxis" in traditional Chinese medicine. Although there are many kinds of drugs used clinically to treat non-allergic purpura, there are many f...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/8905A61P9/14A61P7/04
CPCA61K36/232A61K36/236A61K36/286A61K36/30A61K36/484A61K36/65A61K36/71A61K36/73A61K36/736A61K36/74A61K36/804A61K36/8905A61K2236/331A61K2300/00
Inventor 马力王维蔚齐燕松
Owner 天津市善济宏兴科技发展有限公司